Results 171 to 180 of about 334,426 (343)

Delayed submarine caldera subsidence creates extreme tsunami hazard. [PDF]

Sci Adv
Cronin SJ, Steinke B, Borrero JC, Okal EA, Ribó M, Wu J, White JDL, Brenna M, Paredes-Mariño J, Huebsch M, Baxter R, Speidel U, Van Eaton AR, Mastin LG, Clare MA, Yeo IA, Hunt JE, Nash J, Garvin JB, Vaiomounga R, Kula T, Park SH.   +21 more
europepmc   +1 more source

GHRHR Deficiency Enhances Retinal Ganglion Cell Survival and Visual Functions in Experimental Glaucoma by Inhibiting Ferroptosis

Advanced Science, EarlyView.
Glaucoma, a major cause of blindness, involves retinal ganglion cell (RGC) degeneration. This study shows growth hormone‐releasing hormone receptor (GHRHR) deficiency preserves RGC survival and restores vision, unlike activation which only aids survival.
Yan Tong, Ming Ho Yam, Jiaxin Zhang, Lin Du, Linbin Zhou, Yolanda Wong Ying Yip, Bo Man Ho, Hemlata Bisnauthsing, Jiahui Li, Ivan Kong, Shushu Xu, Changzhen Fu, Karl K.H. So, Joaquim S.L. Vong, Ling‐Ping Cen, Ming‐Ming Yang, Khazeema Yousaf, Mai Har Sham, Sun On Chan, Poemen P. Chan, Chi Pui Pang, Clement C. Tham, Jing Na He, Jian Li, Wai Kit Chu   +24 more
wiley   +1 more source

Discovery of basaltic and magnesian andesite magmas within the Hunga volcanic system, Tonga arc. [PDF]

Sci Rep
Tamura Y, Sato T, Wysoczanski R, Mackay K, McIntosh I, Chang Q, Miyazaki T, Vaglarov B, Hirai Y.   +8 more
europepmc   +1 more source

Integrative Multi‐Omics Analysis Reveals a Mitochondrial–Immune Axis Associated With Neoadjuvant Chemotherapy Response in High‐Grade Serous Ovarian Cancer

Advanced Science, EarlyView.
Integrative multi‐omics analysis delineates a mitochondrial–immune axis governing neoadjuvant chemotherapy response in high‐grade serous ovarian cancer. Immune‐active tumors exhibit enhanced B‐cell infiltration and favorable sensitivity, whereas metabolically rewired tumors display oxidative phosphorylation dependency and resistance.
Wei Jiang, Yi Wang, Xiaohang Lu, Qianlan Yao, Libing Xiang, Xu Cai, Xiaoyu Tu, Shaoxian Tang, Ying Xu, Yufan Cheng, Liming Shen, Huijuan Yang   +11 more
wiley   +1 more source

Metagenomic insights into microbial communities of terrestrial mud volcanos: functional diversity of subsurface archaea and bacteria. [PDF]

Front Microbiol
Kadnikov VV, Mardanov AV, Beletsky AV, Ravin NV.   +3 more
europepmc   +1 more source

Microglial Deubiquitinase OTUD7B Stabilizes STAT3 to Promote Neuroinflammation and Cognitive Decline in Alzheimer's Disease

Advanced Science, EarlyView.
. ABSTRACT Neuroinflammation driven by microglial activation is a defining feature of Alzheimer's disease (AD), yet the molecular mechanisms sustaining this proinflammatory state remain unclear. Here, we identify the deubiquitinase OTUD7B as a critical regulator of microglial activation and AD pathology.
Luyao Li, Hao Tang, Qin Yu, Yuyang Zhang, Binglu Shi, Ying Kong, Leiyu Xu, Jingjing Shao, Chenghong Hu, Lingyu She, Zhe Wang, Haiyi Chen, Aleksandr V. Samorodov, Gang Cao, Xia Zhao, Yi Wang   +15 more
wiley   +1 more source

Inclusive and Collaborative Exergame for Adults With Intellectual and Developmental Disabilities: Development and Usability Study. [PDF]

JMIR Serious Games
Piazzalunga C, Ravazzani S, Romano A, Storti FM, Zelano C, Mencacci E, Giana G, Martinelli O, Galli M, Ferrante S.   +9 more
europepmc   +1 more source

Gradual caldera collapse at Bárdarbunga volcano, Iceland, regulated by lateral magma outflow

Science, 2016
M. Gudmundsson, K. Jónsdóttir, A. Hooper, E. Holohan, S. Halldórsson, B. Ófeigsson, S. Cesca, K. Vogfjörd, F. Sigmundsson, Thórdís Högnadóttir, P. Einarsson, O. Sigmarsson, A. Jarosch, K. Jónasson, E. Magnússon, S. Hreinsdóttir, M. Bagnardi, M. Parks, V. Hjörleifsdóttir, F. Pálsson, T. Walter, Martin P. J. Schöpfer, S. Heimann, H. Reynolds, S. Dumont, E. Bali, G. Gudfinnsson, T. Dahm, M. Roberts, M. Hensch, J. Belart, K. Spaans, S. Jakobsson, G. Gudmundsson, H. Fridriksdóttir, V. Drouin, T. Dürig, G. Aðalgeirsdóttir, M. Riishuus, G. Pedersen, T. van Boeckel, B. Oddsson, M. Pfeffer, S. Barsotti, B. Bergsson, A. Donovan, M. Burton, A. Aiuppa   +47 more
semanticscholar   +1 more source

Selenium Nanoparticles Selectively Target KRAS G13D to Inhibit Colorectal Cancer

Advanced Science, EarlyView.
The mechanisms of SeNPs therapy in cancer treatment, encompass three parallel actions: (1) seleno‐amino acids, key metabolites, upregulate GPX2 expression, thereby inhibiting tumor metastasis via the GPX2‐HIF1α‐VEGF signaling pathway; (2) selenite (SeO32−), an inorganic metabolite, forms hydrogen bonds with amino acid residues 13–17 of the KRAS G13D ...
Xiaoting Liu, Chong Wu, Shiyao Song, Li Ma, Shaoqing Huang, Yuting He, Qinghai Li, Yanzhou Chang, Dan Jiang, Yong Mei, Junchao Cai, Zhenshuang Du, Tianfeng Chen, Weiling He   +13 more
wiley   +1 more source

Alaska Volcano Observatory

This is the homepage of the Alaska Volcano Observatory, a joint program of the United States Geological Survey (USGS), the Geophysical Institute of the University of Alaska Fairbanks (UAFGI), and the State of Alaska Division of Geological and Geophysical

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