Results 211 to 220 of about 355,136 (358)
NOX2 Contributes to High‐Frequency Outer Hair Cell Vulnerability in the Cochlea
This study first identifies NOX2 as a differentially expressed gene related to oxidative damage in the apical and basal turns through single‐cell RNA sequencing. NOX2 gene knockout mitigates OHCs damage caused by neomycin and noise and enhances Nrf2 expression and nuclear translocation.
Meihao Qi+16 more
wiley +1 more source
Volcanic eruptions and the global subsea telecommunications network. [PDF]
Clare MA+22 more
europepmc +1 more source
In this study, Acod1 knockout in CLP mice significantly increases peripheral blood NET levels, exacerbating inflammation, organ damage, and reducing survival. Further research shows that UBR5 interacts with PAD4, a key NET formation protein. Acod1/itaconate (ITA) enhances the enzymatic activity of UBR5 by alkylating the Cys2768 site, promoting the K48 ...
Huifan Liu+10 more
wiley +1 more source
Ongoing multiparameter unrest at the Montagne Pelée volcano on Martinique from 2019 to 2024. [PDF]
Fontaine FR+46 more
europepmc +1 more source
This study identifies alnustone, a natural compound from Alpinia katsumadai, as a potent therapeutic agent for MASLD and MASH. Alnustone enhances mitochondrial fatty acid β‐oxidation by directly targeting calmodulin, improving liver steatosis, fibrosis, and insulin resistance in vivo.
Shourui Hu+13 more
wiley +1 more source
SPOCK Tool for Constructing Empirical Volcano Diagrams from Catalytic Data. [PDF]
Suvarna M+6 more
europepmc +1 more source