Results 261 to 270 of about 355,136 (358)

The Non‐Coding Regulatory Variant rs2863002 at chr11p11.2 Increases Neuroblastoma Risk by Affecting HSD17B12 Expression and Lipid Metabolism

Advanced Science, EarlyView.
The SNP rs2863002 at the 11p11.2 locus, identified through GWAS, is associated with an increased risk of neuroblastoma. The rs2863002‐C allele impairs the binding of the transcription factor GATA3, resulting in upregulation of the HSD17B12 gene.
Teresa Maiorino, Marianna Avitabile, Vincenzo Aievola, Annalaura Montella, Vito A. Lasorsa, Ferdinando Bonfiglio, Mariagrazia Cantalupo, Sueva Cantalupo, Gilda Estinto, Matilde Tirelli, Martina Morini, Martina Ardito, Alessandra Eva, Vincenza Cerbone, Lucia Mauriello, Marianna Caterino, Margherita Ruoppolo, John M. Maris, Sharon J. Diskin, Achille Iolascon, Mario Capasso   +20 more
wiley   +1 more source

Unravel subseafloor hydrothermal leaching and magmatic degassing during chimney formation at Kolumbo volcano. [PDF]

Sci Rep
Hector S, Ahmad Q, Patten CGC, Chiaradia M, Nomikou P, Kilias S, Peillod A, Wagner S, Kolb J.   +8 more
europepmc   +1 more source

UNH Scientist At Mount St Helens To Wire Rumbling Volcano With Microphones [PDF]

, 2004
Sims, David
core   +1 more source

Activation of HTR2B Suppresses Osteosarcoma Progression through the STAT1‐NLRP3 Inflammasome Pathway and Promotes OASL1+ Macrophage Production to Enhance Antitumor Immunity

Advanced Science, EarlyView.
Activation of HTR2B suppresses osteosarcoma progression through the STAT1‐NLRP3 inflammasome pathway and promotes OASL1+ Macrophage production to enhance anti‐tumor immunity. Abstract Osteosarcoma is a primary malignant bone tumor originating from mesenchymal tissue, and associated with poor prognosis.
Zhen Huang, Jiazhuang Zhu, Jianping Hu, Xingkai Wang, Xiaolong Ma, Enjie Xu, Kunpeng Zhu, Chunlin Zhang   +7 more
wiley   +1 more source

Transcriptomics of <i>Pseudomonas aeruginosa</i> PA14 upon deletion of the sigma factor RpoS. [PDF]

Microbiol Resour Announc
Salazar-Garcia LM, Villalobos-Escobedo JM.   +1 more
europepmc   +1 more source

Disruption of ARID1B Recruitment to the Nuclear Pore Complex as a New Anticancer Therapeutic Strategy

Advanced Science, EarlyView.
This study identifies ARID1B as a chromatin‐bound driver of tumor growth in TNBC. ARID1B impairs ARID1A function and directly activates oncogenic programs through SWI/SNF remodeling. Its nuclear localization, mediated by the KPNA2–KPNB1–RANBP2 import machinery, is essential for its tumor‐promoting activity.
Olena Odnokoz, Anupam Banerjee, Xin Cui, Lidan Zeng, Amad Uddin, Christopher Li, Yueming Zhu, Mengyuan Zhang, Xiaodong Lu, Nagendra S. Yarla, Lu Wang, Jindan Yu, Jonathan C. Zhao, Ivet Bahar, Yong Wan   +14 more
wiley   +1 more source

Earthquake clustering and structural modelling unravel volcano-tectonic complexity beneath Mount Etna. [PDF]

Sci Rep
Scarfì L, Barreca G, Cassisi C, Langer H.   +3 more
europepmc   +1 more source

Apoptotic Bodies Restore NAD and Mitochondrial Homeostasis in Fibroblasts

Advanced Science, EarlyView.
Mesenchymal stem cell‐derived apoptotic bodies (MSC‐ABs) target keloid fibroblasts (KFs), restoring nicotinamide adenine dinucleotide (NAD) metabolism and mitochondrial function, suppressing collagen overproduction, and rebalancing tissue homeostasis, offering a novel therapy for keloid.
Shutong Qian, Siya Dai, Chunyi Guo, Wenjun Wang, Jiajia Pang, Yichen Shen, Mingyuan Xu, Jie Hu, Wenguo Cui, Xiaoming Sun, Jinghong Xu   +10 more
wiley   +1 more source

Metabolomics and lipidomics of plasma biomarkers for tuberculosis diagnostics using UHPLC-HRMS. [PDF]

Front Cell Infect Microbiol
Sun G, Wang Q, Shan X, Kuerbanjiang M, Ma R, Zhou W, Sun L, Li Q.   +7 more
europepmc   +1 more source

A High‐Fidelity RNA‐Targeting Cas13X Downregulates Connexin43 in Macroglia: A Novel Neuroprotective Strategy for Glaucoma

Advanced Science, EarlyView.
This study highlights the role of connexin43 (Cx43) in mediating glia activation and neuroinflammation in glaucoma. Using Cx43 knockout mice, it is shown that macroglial cells‐derived Cx43 modulates microglial activation, proliferation, migration, and polarization.
Guoli Zhao, Zhen Li, Ming‐Jie Zhao, Shu‐Ying Li, Qing Xia, Shuoyu Xu, Yu Zhang, Yi Wang, Fang Li, Yu‐Ling Liu, Yun‐Hui Guo, Ruo‐Xi Xu, Han Zhou, Hong Zhou, Wen‐Wen Ding, Yong‐Chen Wang, Yanying Miao, Zhongfeng Wang   +17 more
wiley   +1 more source