Results 21 to 30 of about 336,011 (301)

Obesity alters the fitness of peritumoral adipose tissue, exacerbating tumor invasiveness in renal cancer through the induction of ADAM12 and CYP1B1

open access: yesMolecular Oncology, EarlyView.
Tumor microenvironment drives cancer formation and progression. We analyzed the role of human cancer‐associated adipocytes from patients with renal cell carcinoma (RCC) stratified as lean, overweight, or obese. RNA‐seq demonstrated that, among the most altered genes involved in the tumor–stroma crosstalk, are ADAM12 and CYP1B1, which were proven to be ...
Sepehr Torabinejad   +13 more
wiley   +1 more source

Isogeny volcanoes [PDF]

open access: yesThe Open Book Series, 2013
The remarkable structure and computationally explicit form of isogeny graphs of elliptic curves over a finite field has made them an important tool for computational number theorists and practitioners of elliptic curve cryptography. This expository paper recounts the theory behind these graphs and examines several recently developed algorithms that ...
openaire   +2 more sources

Inhibition of acyl‐CoA synthetase long‐chain isozymes decreases multiple myeloma cell proliferation and causes mitochondrial dysfunction

open access: yesMolecular Oncology, EarlyView.
Triacsin C inhibition of the acyl‐CoA synthetase long chain (ACSL) family decreases multiple myeloma cell survival, proliferation, mitochondrial respiration, and membrane potential. Made with Biorender.com. Multiple myeloma (MM) is an incurable cancer of plasma cells with a 5‐year survival rate of 59%.
Connor S. Murphy   +12 more
wiley   +1 more source

The volcano‐electric effect [PDF]

open access: yesJournal of Geophysical Research: Solid Earth, 2003
The formation of a magmatic intrusion at depth is responsible for the formation of various thermohydromechanical (THM) disturbances including the upsurge of shock waves and diffusion of pressure fronts in the volcanic system. We couple electromagnetic theory (Maxwell equations) and thermoporoelasticity (Biot equations) to look at the ground surface ...
Revil, A.   +2 more
openaire   +7 more sources

Keeping watch over Colombia’s slumbering volcanoes [PDF]

open access: yes, 2015
The Volcanological and Seismological Observatories of Manizales, Pasto and Popayan (Colombian Geological Survey) monitor and study the active volcanoes of Colombia using seismological, geodetic, geochemical and other techniques.
BATTAGLIA, MAURIZIO   +5 more
core   +1 more source

Integration of single‐cell and bulk RNA‐sequencing data reveals the prognostic potential of epithelial gene markers for prostate cancer

open access: yesMolecular Oncology, EarlyView.
Prostate cancer is a leading malignancy with significant clinical heterogeneity in men. An 11‐gene signature derived from dysregulated epithelial cell markers effectively predicted biochemical recurrence‐free survival in patients who underwent radical surgery or radiotherapy.
Zhuofan Mou, Lorna W. Harries
wiley   +1 more source

Acoustic Scattering from Mud Volcanoes and Carbonate Mounts [PDF]

open access: yes, 2006
Submarine mud volcanoes occur in many parts of the world’s oceans and form an aperture for gas and fluidized mud emission from within the earth’s crust.
Etiope, Giuseppe   +2 more
core   +1 more source

Numerical modelling of mud volcanoes and their flows using constraints from the Gulf of Cadiz [PDF]

open access: yes, 2003
It is estimated that the total number of submarine mud volcanoes is between 1000 and 100 000. Because many are associated with greenhouse gases, such as methane, it is argued that the global flux of these gases to the atmosphere from the world’s ...
Blankenship   +14 more
core   +2 more sources

MET variants with activating N‐lobe mutations identified in hereditary papillary renal cell carcinomas still require ligand stimulation

open access: yesMolecular Oncology, EarlyView.
MET variants in the N‐lobe of the kinase domain, found in hereditary papillary renal cell carcinoma, require ligand stimulation to promote cell transformation, in contrast to other RTK variants. This suggests that HGF expression in the microenvironment is important for tumor growth in such patients. Their sensitivity to MET inhibitors opens the way for
Célia Guérin   +14 more
wiley   +1 more source

Volcano remote sensing with ground-based spectroscopy [PDF]

open access: yes, 2005
The chemical compositions and emission rates of volcanic gases carry important information about underground magmatic and hydrothermal conditions, with application in eruption forecasting.
Burton M.R   +5 more
core   +1 more source

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