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Integrated Transcriptome and Metabolomics Analyses Show MYC as a Potential Therapeutic Target for Behçet's Uveitis

open access: yesAdvanced Science, EarlyView.
Integrated single‐cell transcriptomic and metabolomic analyses reveal that MYC‐driven glycolysis activates the PI3K‐AKT‐FOXO1 pathway, disrupting Th17/Treg balance and promoting uveitis. MYC inhibition restores immune homeostasis and alleviates disease symptoms.
He Li   +11 more
wiley   +1 more source
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What is a volcano?

2010
The defi nition of a volcano is discussed, and a new encompassing version is provided. The discussion focuses on the observations that volcanism is a self-similar process that ranges many orders of magnitude in space and time scales, and that all kinds of geologic processes act on volcanoes.
Borgia, Andrea   +3 more
openaire   +4 more sources

Monitoring Volcanoes

Science, 2012
Despite technological advances, volcano monitoring around the world is woefully incomplete.
Sparks, RSJ, Biggs, CJ, Neuberg, J.
openaire   +4 more sources

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