Results 81 to 90 of about 315,759 (374)

Keeping watch over Colombia’s slumbering volcanoes [PDF]

open access: yes, 2015
The Volcanological and Seismological Observatories of Manizales, Pasto and Popayan (Colombian Geological Survey) monitor and study the active volcanoes of Colombia using seismological, geodetic, geochemical and other techniques.
BATTAGLIA, MAURIZIO   +5 more
core   +1 more source

Integration of single‐cell and bulk RNA‐sequencing data reveals the prognostic potential of epithelial gene markers for prostate cancer

open access: yesMolecular Oncology, EarlyView.
Prostate cancer is a leading malignancy with significant clinical heterogeneity in men. An 11‐gene signature derived from dysregulated epithelial cell markers effectively predicted biochemical recurrence‐free survival in patients who underwent radical surgery or radiotherapy.
Zhuofan Mou, Lorna W. Harries
wiley   +1 more source

MET variants with activating N‐lobe mutations identified in hereditary papillary renal cell carcinomas still require ligand stimulation

open access: yesMolecular Oncology, EarlyView.
MET variants in the N‐lobe of the kinase domain, found in hereditary papillary renal cell carcinoma, require ligand stimulation to promote cell transformation, in contrast to other RTK variants. This suggests that HGF expression in the microenvironment is important for tumor growth in such patients. Their sensitivity to MET inhibitors opens the way for
Célia Guérin   +14 more
wiley   +1 more source

Characterizing analogue caldera collapse with computerized X-ray tomography [PDF]

open access: yes, 2013
Analogue models of caldera collapse were imaged by computerized X-ray tomography (μCT). Interval μCT radiography sequences document ‘2.5D’ surface and internal model deformation in an unprecedented way, and carry the potential for a better understanding ...
Boone, Matthieu   +4 more
core   +1 more source

Response to neoadjuvant chemotherapy in early breast cancers is associated with epithelial–mesenchymal transition and tumor‐infiltrating lymphocytes

open access: yesMolecular Oncology, EarlyView.
Epithelial–mesenchymal transition (EMT) and tumor‐infiltrating lymphocytes (TILs) are associated with early breast cancer response to neoadjuvant chemotherapy (NAC). This study evaluated EMT and TIL shifts, with immunofluorescence and RNA sequencing, at diagnosis and in residual tumors as potential biomarkers associated with treatment response.
Françoise Derouane   +16 more
wiley   +1 more source

Chemistry, Growth, and Fate of the Unique, Short‐Lived (2019–2020) Water Lake at the Summit of Kīlauea Volcano, Hawaii

open access: yesGeochemistry, Geophysics, Geosystems
Less than a year after the 2018 Kīlauea caldera collapse and eruption, water appeared in newly deepened Halemaʻumaʻu crater. The lake—unprecedented in the written record—grew to a depth of ∼50 m before lava from the December 2020 eruption boiled it away.
P. A. Nadeau   +8 more
doaj   +1 more source

Pyroclastic density currents associated with the 2015 phreatomagmatic eruption of the Kuchinoerabujima volcano

open access: yesEarth, Planets and Space, 2018
A pyroclastic density current (PDC) was observed with the phreatomagmatic eruption of the Kuchinoerabujima volcano, southern Japan, on May 29, 2015. The PDC flowed down in all direction from the source crater, forming three major branches.
Nobuo Geshi, Jun’ichi Itoh
doaj   +1 more source

TOMM20 as a driver of cancer aggressiveness via oxidative phosphorylation, maintenance of a reduced state, and resistance to apoptosis

open access: yesMolecular Oncology, EarlyView.
TOMM20 increases cancer aggressiveness by maintaining a reduced state with increased NADH and NADPH levels, oxidative phosphorylation (OXPHOS), and apoptosis resistance while reducing reactive oxygen species (ROS) levels. Conversely, CRISPR‐Cas9 knockdown of TOMM20 alters these cancer‐aggressive traits.
Ranakul Islam   +9 more
wiley   +1 more source

Automatic identification and quantification of volcanic hotspots in Alaska using HotLINK: the hotspot learning and identification network

open access: yesFrontiers in Earth Science
An increase in volcanic thermal emissions can indicate subsurface and surface processes that precede, or coincide with, volcanic eruptions. Space-borne infrared sensors can detect hotspots—defined here as localized volcanic thermal emissions—in near-real-
Pablo Saunders-Shultz   +3 more
doaj   +1 more source

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