Results 81 to 90 of about 334,426 (343)

Profiling neoadjuvant therapy response in rectal cancer using meta‐analysis of publicly available transcriptomic RNA‐seq datasets

Molecular Oncology, EarlyView.
This study integrates publicly available transcriptomic datasets to identify molecular signatures associated with response to neoadjuvant chemoradiotherapy in locally advanced rectal cancer. By analyzing a combination of multiple cohorts with bioinformatics approaches, we reveal biological pathways and immune‐related features that may improve ...
Aleksandra Stanojevic, Rafael Stroggilos, Mladen Marinkovic, Ana Djuric, Suzana Stojanovic‐Rundic, Radmila Jankovic, Sergi Castellvi‐Bel, Remond J.A. Fijneman, Antonia Vlahou, Jerome Zoidakis, Milena Cavic   +10 more
wiley   +1 more source

Magma-Carbonate Interaction at Merapi Volcano, Indonesia

, 2023
Merapi volcano, Indonesia, is a highly active arc volcano built upon a crustal succession that includes thick carbonate sequences. Calc-silicate (skarn) xenoliths are frequently found in Merapi’s erupted products and constitute direct evidence for magma ...
Freda, Carmela,, Gertisser, Ralf,, Troll, Valentin R.,, Deegan, Frances M.,   +3 more
core   +1 more source

p190A/ARHGAP35 and p190B/ARHGAP5 proteins in endometrial cancer: a novel cancer‐relevant paralog interplay

Molecular Oncology, EarlyView.
This study identifies ARHGAP5, in addition to the frequently mutated ARHGAP35, as significantly mutated in endometrial cancer. Mutations in both genes co‐occur and are associated with their correlated downregulation. Functional CRISPR studies show that both paralogs regulate similar pathways, including actin cytoskeleton organization.
Mathilde Pinault, Capucine Heraud, Mélissa Correia de Oliveira, Véronique Neaud, Valérie Valesco, Valérie Prouzet‐Mauleon, Béatrice Turcq, Jean‐William Dupuy, Anne‐Aurélie Raymond, Sabrina Croce, Frédéric Saltel, Valérie Lagrée, Violaine Moreau   +12 more
wiley   +1 more source

Upper crustal structure of an active volcano from refraction/reflection tomography, Montserrat, Lesser Antilles [PDF]

, 2010
To better understand the volcanic phenomena acting on Montserrat, the SEA-CALIPSO seis-mic experiment (Seismic Experiment with Airgun-source – Caribbean Andesitic Lava Island Precision Seismo-geodetic Observatory) was conducted in 2007 December with the ...
Henstock, T, Kiddle, E.J., Kenedi, CL, Baptie, Brian, Hammond, J.O.S., Minshull, T., Henstock, T., Malin, Peter, Ryan, G., Paulatto, M, Shalev, E, Hammond, James O.S., Hammond, JOS, Paulatto, Michele, Baptie, B., Dean, S, Minshull, T. A., Kiddle, E., Minshull, TA, Malin, P, Voight, B., Paulatto, M., Minshull, T.A., Voight, B, Sparks, R.S.J., Kenedi, C., Dean, S., Sparks, RSJ, Shalev, E., Peirce, C., Baptie, B, Kenedi, C.L., Malin, P., Kiddle, EJ, Ryan, G, Peirce, C   +35 more
core   +1 more source

Time‐restricted feeding prior to Mycobacterium tuberculosis infection reduces tissue CD4+ T cells with limited impact on bacterial clearance

FEBS Open Bio, EarlyView.
Time‐restricted feeding (TRF) in mice increased liver fatty acid oxidation and decreased fatty acid biosynthesis. These alterations persisted when TRF was discontinued and the host was infected with Mycobacterium tuberculosis. Pre‐exposure to TRF did not alter tissue (lung and spleen) mycobacterial burden but significantly reduced CD3+ T cells in lungs
Ashish Gupta, Nidhi Yadav, Subhasmita Das, R. Rajendra Kumar Reddy, Nupur Sharma, Amol Ratnakar Suryawanshi, Jaswinder Singh Maras, Ranjan Kumar Nanda   +7 more
wiley   +1 more source

Loss of AMBRA1 activates MAPK and angiogenesis signaling pathways in melanoma cells

FEBS Open Bio, EarlyView.
Loss of AMBRA1 in melanoma cells activates multiple oncogenic pathways associated with tumor progression. Transcriptomic and protein network analyses revealed that AMBRA1 depletion enhances MAPK/ERK signaling, angiogenesis, TGF‐β/EMT signaling, and Wnt/axon guidance pathways.
Milad Ibrahim, Marco Corazzari, Iman Osman, Jane Armstrong, Noel Carter   +4 more
wiley   +1 more source

pklemmer/Generating volcano plots from expression data

, 2022
This repository contains an R script for (GEO2R rotenone) dataset volcano plot generation in addition to GEO 2 R rotenone exposure expression datasets (tsv) as well as the corresponding volcano plots (svg)
Pierre Klemmer
core   +1 more source

Pyroclastic density currents associated with the 2015 phreatomagmatic eruption of the Kuchinoerabujima volcano

Earth, Planets and Space, 2018
A pyroclastic density current (PDC) was observed with the phreatomagmatic eruption of the Kuchinoerabujima volcano, southern Japan, on May 29, 2015. The PDC flowed down in all direction from the source crater, forming three major branches.
Nobuo Geshi, Jun’ichi Itoh
doaj   +1 more source

Taking the pulse of Mars via dating of a plume-fed volcano

Nature Communications, 2017
Mars hosts the solar system’s largest volcanoes. Although their size and impact crater density indicate continued activity over billions of years, their formation rates are poorly understood.
B. Cohen, D. Mark, W. Cassata, Martin R. Lee, T. Tomkinson, Caroline L. Smith   +5 more
semanticscholar   +1 more source

Chemistry, Growth, and Fate of the Unique, Short‐Lived (2019–2020) Water Lake at the Summit of Kīlauea Volcano, Hawaii

Geochemistry, Geophysics, Geosystems
Less than a year after the 2018 Kīlauea caldera collapse and eruption, water appeared in newly deepened Halemaʻumaʻu crater. The lake—unprecedented in the written record—grew to a depth of ∼50 m before lava from the December 2020 eruption boiled it away.
P. A. Nadeau, S. Hurwitz, S. Peek, A. H. Lerner, E. F. Younger, M. R. Patrick, D. E. Damby, R. B. McCleskey, P. J. Kelly   +8 more
doaj   +1 more source