Results 91 to 100 of about 627,703 (284)

A Spatially Directed Microneedle Patch Enables Intratumoral Co‐Delivery of FOLFIRINOX, Surufatinib, and Anti‐PD‐1 for Chemo‐Immunotherapy of Pancreatic Ductal Adenocarcinoma

open access: yesAdvanced Science, EarlyView.
A double‐layered shell‐core microneedle patch is developed to co‐deliver FOLFIRINOX, surufatinib, and anti‐PD‐1 for localized chemo‐immunotherapy of PDAC. This strategy achieves sustained tumor suppression, reduces metastasis, and reprograms the TME by enhancing CD8+ T‐cell infiltration and inhibiting Tregs and M2 macrophages infiltration, while ...
Tingting Kong   +13 more
wiley   +1 more source

Improved artificial bee colony algorithm for pressure source parameter inversion of Sakurajima volcano from InSAR data

open access: yesGeodesy and Geodynamics
A novel artificial bee colony algorithm was introduced for the eruption event of the Sakurajima volcano on August 9, 2020, to invert the magma source characteristics below the volcano based on the point source Mogi model.
Leyang Wang, Linghui Xie, Can Xi
doaj   +1 more source

Multi-Sensor SAR Geodetic Imaging and Modelling of Santorini Volcano Post-Unrest Response

open access: yesRemote Sensing, 2019
Volcanic history of Santorini over recent years records a seismo-volcanic unrest in 2011⁻12 with a non-eruptive behavior. The volcano deformation state following the unrest was investigated through multi-sensor Synthetic Aperture Radar ...
Elena Papageorgiou   +5 more
doaj   +1 more source

EphB1‐Mediated Transient Blood‐Brain Barrier Opening Facilitates a Ferritin‐Based Nanotherapeutic for Alzheimer's Disease

open access: yesAdvanced Science, EarlyView.
We constructed a brain‐targeted AFn‐DPZ nanodrug delivery system and identified EphB1 as its receptor on the blood‐brain barrier (BBB). This system facilitates drug transport across the BBB and thereby ameliorates cognitive impairment in Alzheimer's disease.
Shilin Wen   +5 more
wiley   +1 more source

Understanding creep in sandstone reservoirs – theoretical deformation mechanism maps for pressure solution in granular materials [PDF]

open access: yes, 2014
Subsurface exploitation of the Earth’s natural resources removes the natural system from its chemical and physical equilibrium. As such, groundwater extraction and hydrocarbon production from subsurface reservoirs frequently causes surface subsidence and
Hangx, Suzanne   +2 more
core  

Overcoming the Catalytic Bucket Effect in Pt‐based High‐Entropy Nanocages Through Interface Defect and Strain Engineering

open access: yesAdvanced Science, EarlyView.
PtPdNiCuMnAu HENCs exhibit a remarkable half‐wave potential (E1/2) of 0.925 V vs. RHE. The catalyst displays exceptional electrochemical stability, with only a 4 mV negative shift in E1/2 and a mere 5.6% loss in MA after 10, 000 accelerated durability test cycles.
Qian Liu   +5 more
wiley   +1 more source

Twelve Years of Ground Deformation Studies on Mt. Etna Volcano Based on GPS Surveys

open access: yes, 2004
GPS (Global Positioning System) monitoring has been performed on Etna volcano since 1988, making this volcano one of those with the longest records of GPS data.
Puglisi, G., Briole, P., Bonforte, A.
core   +1 more source

Independent component analysis and finite element modelling of the 2004–2005 ground deformation in Tenerife (Canary Islands)

open access: yesFrontiers in Earth Science
Historic volcanic activity in Tenerife was concentrated within two of the island’s three dorsals and on the Teide-Pico Viejo complex located inside Las Cañadas caldera.
Monika Przeor   +10 more
doaj   +1 more source

Deformations and Morphology Changes Associated with the 2016–2017 Eruption Sequence at Bezymianny Volcano, Kamchatka

open access: yesRemote Sensing, 2019
Lava domes grow by extrusions and intrusions of viscous magma often initiating from a central volcanic vent, and they are frequently defining the source region of hazardous explosive eruptions and pyroclastic density currents.
René Mania   +4 more
doaj   +1 more source

CALB2 is a Mechanoresistance Gene in Metastatic Prostate Cancer

open access: yesAdvanced Science, EarlyView.
Prostate cancer cell lines of differing origins were cultured over many passages while being subjected to semi‐lethal levels of fluid shear stress, representing the harsh mechanical environment these cells are subjected to in the circulation during the process of distant metastasis.
Abigail R. Fabiano   +10 more
wiley   +1 more source

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