Results 141 to 150 of about 3,707,657 (314)

The Super Enhancer‐Driven Long Noncoding RNA PRKCQ‐AS1 Promotes Neuroblastoma Tumorigenesis by Interacting With MSI2 Protein and Is Targetable by Small Molecule Compounds

Advanced Science, EarlyView.
PRKCQ‐AS1 is overexpressed due to transcriptional super‐enhancers. PRKCQ‐AS1 RNA forms a complex with MSI2 protein to induce BMX mRNA stabilization and overexpression, ERK protein phosphorylation and neuroblastoma cell proliferation. Compound NSC617570 blocks PRKCQ‐AS1 binding to MSI2, leading to BMX mRNA disassociation from MSI2 protein, BMX reduction,
Sujanna Mondal, Pei Y. Liu, Janith Seneviratne, Antoine De Weck, Pooja Venkat, Chelsea Mayoh, Jing Wu, Jesper Maag, Jingwei Chen, Matthew Wong, Nenad Bartonicek, Poh Khoo, Lei Jin, Louise E. Ludlow, David S. Ziegler, Toby Trahair, Pieter Mestdagh, Belamy B. Cheung, Jinyan Li, Marcel E. Dinger, Ian Street, Xu D. Zhang, Glenn M. Marshall, Tao Liu   +23 more
wiley   +1 more source

Low-cost GPS-based volcano deformation monitoring at Mt. Papandayan, Indonesia [PDF]

, 2002
Volker Janssen, Craig Roberts, Chris Rizos, Hasanuddin Z. Abidin   +3 more
openalex   +1 more source

Gut Microbiota Colonization in Early Life Influences Susceptibility to Adulthood Hepatic Lipid Accumulation in High‐Fat‐Diet‐Fed Mice

Advanced Science, EarlyView.
This study indicates that perinatal antibiotic exposure elevates susceptibility to high‐fat‐diet‐induced hepatic lipid accumulation via disrupting early‐life gut microbiota colonization. The decreased Lactobacillus colonization inhibits primary‐to‐secondary bile acid conversion, lowering secondary bile acids, enhancing adulthood intestinal lipid ...
Yan‐Yan Zhu, Xin Dong, Hao Zhou, Ze‐Yan Li, Bo Wang, Ya‐Ping Song, Zhi‐Bing Liu, Xue Lu, Yi‐Hao Zhang, Yichao Huang, Hua Wang, De‐Xiang Xu   +11 more
wiley   +1 more source

A Framework for Real-Time Volcano-Seismic Event Recognition Based on Multi-Station Seismograms and Semantic Segmentation Models [PDF]

arXiv
In volcano monitoring, effective recognition of seismic events is essential for understanding volcanic activity and raising timely warning alerts. Traditional methods rely on manual analysis, which can be subjective and labor-intensive. Furthermore, current automatic approaches often tackle detection and classification separately, mostly rely on single
arxiv  

Toward Creating Subsurface Camera [PDF]

arXiv, 2018
In this article, the framework and architecture of Subsurface Camera (SAMERA) is envisioned and described for the first time. A SAMERA is a geophysical sensor network that senses and processes geophysical sensor signals, and computes a 3D subsurface image in-situ in real-time.
arxiv  

Seafloor seismic monitoring of an active submarine volcano: Local seismicity at Vailulu'u Seamount, Samoa [PDF]

, 2004
J. G. Konter, Hubert Staudigel, Stanley R. Hart, Peter M. Shearer   +3 more
openalex   +1 more source

Targeting Senescence with Apigenin Improves Chemotherapeutic Efficacy and Ameliorates Age‐Related Conditions in Mice

Advanced Science, EarlyView.
As a plant‐derived flavonoid, apigenin directly targets PRDX6 to inhibit its PLA2 activity, blocking HSPA8 activation and disturbing its interactions with ATM and p38MAPK in senescent cells. By dampening wide spectrum expression of the SASP, apigenin prevents loss of tissue homeostasis, improves organ function, and alleviates multiple age‐related ...
Hongwei Zhang, Qixia Xu, Zhirui Jiang, Rong Sun, Qun Wang, Sanhong Liu, Xin Luan, Judith Campisi, James L. Kirkland, Weidong Zhang, Yu Sun   +10 more
wiley   +1 more source

Revealing spatio-temporal variations of soil CO2 flux at Mt. Etna volcano

Results in Earth Sciences
Over the past two decades, significant advances in the geochemical monitoring of volcanoes have shown how crucial the observation of specific geochemical tracers is for understanding and evaluating eruptive processes.
Salvatore Scudero, Marco Liuzzo, Antonino D’Alessandro, Giovanni Giuffrida, Sergio Gurrieri   +4 more
doaj  

X-ray/gamma-ray flux correlations in the BL Lacs Mrk 421 and 501 using HAWC data [PDF]

arXiv, 2017
The HAWC gamma ray observatory is located at the Sierra Negra Volcano in Puebla, Mexico, at an altitude of 4,100 meters. HAWC is a wide field of view array of 300 water Cherenkov detectors that are continuously surveying ~ 2sr of the sky, operating since March 2015. The large collected data sample allows HAWC to perform an unbiased monitoring of the BL
arxiv  

Volcano deformation: geodetic monitoring techniques [PDF]

, 2007
Daniel Dzurisin
openalex   +1 more source