Results 161 to 170 of about 3,707,657 (314)

Alaska GeoSurvey News - The Alaska Volcano Observatory - 20 years of volcano research, monitoring, and eruption response [PDF]

, 2008
C. J. Nye, J. R. Schaefer
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Vessel‐On‐A‐Chip Coupled Proteomics Reveal Pressure‐Overload‐Induced Vascular Remodeling

Advanced Science, EarlyView.
A vessel‐on‐a‐chip system is developed to replicate both physiological and pathological vessel cyclic stretches. Proteomic analysis reveals pressure‐overload‐induced vascular remodeling, including cellular response to mechanical cues, cellular oxidative stresses, ER stress, and ceramide biosynthesis activation in the vessel‐on‐a‐chip system, well ...
Yanjun Liu, Jianxujie Zheng, Lingyan Zhong, Zengyu Wang, Dan Zhao, Hong Lin, Xiaoxue Zhang, Ke Meng, Xiaoxia Yang, Dongxue Zhang, Ling Lin, Liang Qiao   +11 more
wiley   +1 more source

Continuous thermal monitoring of the 2008 eruptions at Showa crater of Sakurajima volcano, Japan [PDF]

, 2009
Akihiko Yokoo
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MeCP2 Lactylation Protects against Ischemic Brain Injury by Transcriptionally Regulating Neuronal Apoptosis

Advanced Science, EarlyView.
MeCP2 lactylation protects against ischemic stroke by reducing brain infarct volume and improving neurological outcomes. Lactylation at K210/K249 exerts neuroprotective effects by repressing the transcription of apoptosis‐associated genes, including Pdcd4 and Pla2g6. HDAC3 and p300 serve as key regulatory enzymes for MeCP2 lactylation following stroke.
Min Sun, Yuxin Zhang, Rui Mao, Yan Chen, Pinyi Liu, Lei Ye, Siyi Xu, Junqiu Jia, Shu Shu, Huiya Li, Yanping Yin, Shengnan Xia, Yanting Chen, Yun Xu   +13 more
wiley   +1 more source

Diallyl Trisulfide From Garlic Regulates RAB18 Phase Separation to Inhibit Lipophagy and Induce Cuproptosis in Hepatic Stellate Cells for Antifibrotic Effects

Advanced Science, EarlyView.
Diallyl trisulfides (DATs) selectively induce cuproptosis in hepatic stellate cells (HSCs) by targeting Ras‐related protein Rab‐18 (RAB18) and regulating lipophagy. DATs promote RAB18 phase separation, enhance mitochondrial‐associated membrane structures (MAMs) formation, and increase succinylation of dihydrolipoamide dehydrogenase (DLD) at K320.
Haoyuan Tian, Shujiang Sun, Xinran Qiu, Junrui Wang, Yuanyuan Gao, Jianmei Chen, Xiang Han, Zhengyang Bao, Xiaohan Guo, Yuqi Sun, Yuxin Lin, Mengru Hu, Feng Zhang, Zili Zhang, Feixia Wang, Shizhong Zheng, Jiangjuan Shao   +16 more
wiley   +1 more source

In Vivo Reprogramming of Tissue‐Derived Extracellular Vesicles for Treating Chronic Tissue Injury Through Metabolic Engineering

Advanced Science, EarlyView.
Inspired by exercise‐induced metabolic rewiring and EV secretion, this study shows that in vivo metabolic engineering strategy can reprogram EV secretion pattern and simultaneously attenuate multiple tissue injury in CKD status, highlighting that it is a potential strategy for treating diverse chronic diseases.
Meng Zhao, Shuyun Liu, Yizhuo Wang, Peng Lou, Ke Lv, Tian Wu, Lan Li, Qianyi Wu, Jiaying Zhu, Yanrong Lu, Meihua Wan, Jingping Liu   +11 more
wiley   +1 more source

Interrogating the impact of aggregation‐induced emission nanoparticles on in vitro protein stability, ex vivo protein homeostasis, and in vivo biocompatibility

Aggregate, Volume 3, Issue 6, December 2022., 2022
Investigation of how the AIE molecules and functionalized AIE nanoparticle impact protein stability, protein homeostasis in cells, biodistribution, and biocompatibility in animal model. Abstract Aggregation‐induced emission (AIE) materials offer promising perspectives in disease diagnosis and therapeutics given their unique optical and photochemical ...
Wang Wan, Qun Zhao, Biao Jing, Congcong Peng, Mengdie Wang, Yanan Huang, Wenhan Jin, Bowen Zhong, Zhenduo Zhang, Xuepeng Dong, Zhenming Gao, Lihua Zhang, Yu Liu   +12 more
wiley   +1 more source

Kelut volcano monitoring: Hazards, mitigation and changes in water chemistry prior to the 1990 eruption.

, 1994
Muhammad Badrudin
openalex   +2 more sources

The Study on the Possibility of Using Satellite in Monitoring Precursor of Magma Activity in the Baegdusan Volcano [PDF]

, 2013
Deok-Su Lee, Sungchan Choi, Chang‐Whan Oh, Min‐Ho Seo, In‐Chang Ryu   +4 more
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Homocysteine Promotes the Pathogenesis of Atherosclerosis through the Circ‐PIAS1‐5/miR‐219a‐2‐3p/TEAD1 Axis

Advanced Science, EarlyView.
A model is schematically represented for the major molecular mechanisms by which homocysteine (Hcy) accelerates the nuclear export of circ‐PIAS1‐5, which regulates atherosclerosis by acting as a competing endogenous RNA for miR‐219a‐2‐3p. Hcy enrichment of circ‐PIAS1‐5 leads to YTHDC1 binding to circ‐PIAS1‐5 and promotes its intracellular localization ...
Shengchao Ma, Fei Ma, Ning Ding, Lin Xie, Anning Yang, Jiangyong Shen, Yun jiao, Kai Wu, YueE Chai, Zhigang Bai, Jiantuan Xiong, Nan Li, Huiping Zhang, Yideng Jiang   +13 more
wiley   +1 more source