Results 171 to 180 of about 70,139 (338)

Discovery of Natural Compound α‐Hederin via Large‐Scale Screening as a Targeted JAK/STAT3 Inhibitor for Ovarian Cancer Therapy

Advanced Science, EarlyView.
This study identifies α‐Hederin as a potent dual JAK1/JAK2 inhibitor that blocks STAT3 activation in ovarian cancer. By disrupting STAT3‐driven transcriptional programs, α‐Hederin suppresses tumor proliferation, invasion, and EMT, while enhancing cisplatin efficacy and overcoming chemoresistance.
Jiayu Wang, Pengzhan He, Cheng Liu, Xin Chen, Yilin Tan, Rui Qu, Yan Zhang, Zhou Li, Tailang Yin, Zhinang Yin   +9 more
wiley   +1 more source

Seismic equivalents of volcanic jet scaling laws and multipoles in acoustics [PDF]

, 2017
Aldridge, David F, Fee, David, Haney, Matthew M, Matoza, Robin S   +3 more
core   +2 more sources

Design of Deformation Monitoring System for Volcano Mitigation [PDF]

, 2016
Mohammad Ruqy Faishal Islamy, Rahmat Awaludin Salam, Muhammad Miftahul Munir, M. Irsyam, Khairurrijal Khairurrijal   +4 more
openalex   +1 more source

In Situ Proliferating Peptide Nanoparticle Augments Multi‐Target Intervention of Secondary Brain Damage Following Subarachnoid Hemorrhage

Advanced Science, EarlyView.
This work designs an in situ proliferating peptide nanoparticle as a flexible resolution that modulates the neuro‐glia unit to enable enhanced multi‐target combinational therapy for secondary brain damage following subarachnoid hemorrhage. Abstract Subarachnoid hemorrhage (SAH), a lethal stroke subtype, involves complex pathological cascades triggered ...
Yibin Zhang, Peisen Yao, Fuxiang Chen, Shufa Zheng, Xuegang Niu, Haojie Wang, Yuanxiang Lin, Bin Gao, Dezhi Kang   +8 more
wiley   +1 more source

Global Volcano Monitoring: What Does It Mean When Volcanoes Deform? [PDF]

, 2017
Juliet Biggs, M. E. Pritchard
openalex   +1 more source

Integrated Transcriptome and Metabolomics Analyses Show MYC as a Potential Therapeutic Target for Behçet's Uveitis

Advanced Science, EarlyView.
Integrated single‐cell transcriptomic and metabolomic analyses reveal that MYC‐driven glycolysis activates the PI3K‐AKT‐FOXO1 pathway, disrupting Th17/Treg balance and promoting uveitis. MYC inhibition restores immune homeostasis and alleviates disease symptoms.
He Li, Lei Zhu, Zhaohuai Li, Yihan Zhang, Genxian Zhang, Xuening Peng, Dongting Wu, Qi Jiang, Rong Wang, Renbing Jia, Song Guo Zheng, Wenru Su   +11 more
wiley   +1 more source

Monitoring of the Nirano Mud Volcanoes Regional Natural Reserve (North Italy) using Unmanned Aerial Vehicles and Terrestrial Laser Scanning [PDF]

, 2017
Tommaso Santagata
openalex   +1 more source

MTCH2 Deficiency Promotes E2F4/TFRC‐Mediated Ferroptosis and Sensitizes Colorectal Cancer Liver Metastasis to Sorafenib

Advanced Science, EarlyView.
This study identifies MTCH2 as a crucial regulator of ferroptosis in colorectal cancer (CRC) progression. High expression of MTCH2 is correlated with poor prognosis in CRC patients. Furthermore, MTCH2 depletion induces ferroptosis to suppress CRC liver metastasis via the E2F4/TFRC axis and sensitizes tumors to sorafenib treatment, supporting MTCH2 as a
Pu Xing, Jiangbo Chen, Hao Hao, Xiaowen Qiao, Xinying Yang, Kai Weng, Jie Chen, Lin Song, Tianqi Liu, Yifan Hou, Tongkun Song, Yumeng Ran, Bo Chen, Hong Yang, Wei Zhao, Zaozao Wang, Jiabo Di, Beihai Jiang, Xiangqian Su   +18 more
wiley   +1 more source

Use of MODIS images to study eruptive clouds from Volcán de Fuego de Colima (México) and applications on volcano monitoring

, 2011
José Carlos Jiménez-Escalona, Hugo Delgado Granados, Vincent J. Realmuto   +2 more
openalex   +2 more sources

Significant Release of Dissolved Inorganic Nutrients From the Shallow Submarine Volcano Tagoro (Canary Islands) Based on Seven-Year Monitoring [PDF]

, 2020
Alba González‐Vega, E. Fraile‐Nuez, J. Magdalena Santana‐Casiano, Melchor González‐Dávila, José Escánez-Pérez, M. Gómez-Ballesteros, Olvido Tello, Jesús M. Arrieta   +7 more
openalex   +1 more source