Results 181 to 190 of about 70,139 (338)

Nrf2 Drives Epigenetic Reprogramming and Acts as the Master Regulator of KLF4 Expression and Activity in Arsenic‐Induced Transformation

Advanced Science, EarlyView.
Nrf2 isn't just a protector—it's a driver of cancer stemness. The study uncovers how arsenic‐activated Nrf2 directly upregulates KLF4, a key pluripotency factor, fueling oncogenic reprogramming. Through enhancer activation and self‐reinforcing loop, Nrf2 and KLF4 co‐opt gene networks linked to epithelial‐to‐mesenchymal transition and tumor growth ...
Ziwei Wang, Zhuoyue Bi, Jessica Bamrah, Yiran Qiu, Wenxuan Zhang, Bandar Saeed Almutairy, Haoyan Ji, John D. Haley, Chitra Thakur, Fei Chen   +9 more
wiley   +1 more source

The University of the West Indies-Seismic Research Centre Volcano Monitoring Network: Evolution since 1953 and Challenges in Maintaining a State-of-the-Art Network in a Small Island Economy [PDF]

, 2019
Frédéric Dondin, Lloyd Lynch, Chan Ramsingh, G. Ryan, Ilias Papadopoulous, Daniel Rueppel, Erouscilla P. Joseph, Joan L. Latchman, Richard Robertson, Nisha Nath, Ranissa Mathura, Amit Balchan, Stephen George, Ian Juman, Farrah Madoo, Garth Manette, Hannah Ramsingh   +16 more
openalex   +1 more source

The 2019 Eruption Dynamics and Morphology at Ebeko Volcano Monitored by Unoccupied Aircraft Systems (UAS) and Field Stations [PDF]

, 2020
Thomas R. Walter, Alexander Belousov, Marina Belousova, Т. А. Котенко, Andreas Auer   +4 more
openalex   +1 more source

Nanoparticle‐Mediated CXCL12–CXCR4 Inhibition Reprograms Macrophages and Suppresses Gastric Carcinoma

Advanced Science, EarlyView.
Molecular mechanism study of self‐assembled M2pep‐Cs NPs/Plerixafor nanoparticles in targeting MΦ reprogramming by regulating the CXCL12–CXCR4 signaling pathway to enhance immune recognition and clearance of GC (Created by BioRender). Abstract Gastric carcinoma (GC) remains a major global health challenge, requiring novel therapeutic approaches.
Qianqian Cao, Xiaolei Cheng, Rongbin Lv, Dianshui Sun, Jihua Wang, Runjia Fu, Rumei Gong, Yueying Xiao, Qin Liu, Xiaomei Li   +9 more
wiley   +1 more source

Ongoing multiparameter unrest at the Montagne Pelée volcano on Martinique from 2019 to 2024. [PDF]

Sci Rep
Fontaine FR, Komorowski JC, Corbeau J, Burtin A, de Chabalier JB, Grandin R, Saurel JM, Agrinier P, Moune S, Jadelus F, Melezan D, Gabriel JG, Vidal C, Zimmermann B, Vaton D, Koziol J, Lavenaire JM, Moretti R, Lemarchand A, Labasque T, Blard PH, Tibari B, Zimmermann L, Aubaud C, Vergne J, Andrieu A, Filliaert A, Chilin-Eusebe E, Wahlgren SZ, Inostroza M, Métaxian JP, Potier A, Fernandez I, Robert V, Deroussi S, Carazzo G, Tait S, Vlastelic I, Jessop DE, Bonaimé S, Le Friant A, Chaussidon M, Michaud-Dubuy A, Retailleau L, Di Muro A, Allard P, Satriano C.   +46 more
europepmc   +1 more source

Landform monitoring in active volcano by UAV and SfM-MVS technique

, 2014
Takayuki Nakano, Izumi Kamiya, Mikio Tobita, Junko Iwahashi, Hidetoshi Nakajima   +4 more
openalex   +1 more source

Continuous monitoring of soil CO2 flux at Aso volcano, Japan: the influence of environmental parameters on diffuse degassing [PDF]

, 2019
Masaaki Morita, Toshiya Mori, Akihiko Yokoo, Takahiro Ohkura, Yuichi Morita   +4 more
openalex   +1 more source

PTf‐SRiApt Targeting SCAF4‐POLR2A Interaction Suppresses Tumor Growth and Promotes Antitumor Immunity in Triple‐Negative Breast Cancer

Advanced Science, EarlyView.
A phosphorothioate‐modified aptamer PTf‐SRiApt capable of disrupting “undruggable” transcription factor SCAF4‐POLR2A interaction with high inhibitory activity and biological stability is presented here. Through this inhibition, PTf‐SRiApt successfully arrested cell cycle progression, induced cell death, and elevated immune recruitment in SCAF4‐POLR2A ...
Liyan Fei, Yichun Pan, Jie Zhai, Tongqing Li, Yuxin Zhou, Sheyu Zhang, Juan Wei, Qian Hu, Xueying Liu, Lu Guo, Weizhu Wu, Yong Wei, Qin Wu, Weihong Tan   +13 more
wiley   +1 more source

Volcanic eruptions and the global subsea telecommunications network. [PDF]

Bull Volcanol
Clare MA, Yeo IA, Nash J, Hunt JE, Panuve S, Wilkie A, Williams R, Dowey N, Rowley P, Barclay J, Phillips J, Scarlett J, Engwell S, Henstock TJ, Seabrook S, Watson S, Wysoczanski R, Ribo M, Cronin S, Talling PJ, Cassidy M, Watt S, Robertson R.   +22 more
europepmc   +1 more source

Identifying Myeloid‐Derived Suppressor Cells and Lipocalin‐2 as Therapeutic Targets for Intervertebral Disc Degeneration

Advanced Science, EarlyView.
Inflammatory dysregulation drives intervertebral disc degeneration via stage‐dependent immune cellular dynamics. Single‐cell transcriptomics and genetic risk mapping revealed a shift from LCN2high myeloid‐derived suppressor cells maintaining disc repair in early stages to IL1B+ macrophage‐dominated pathology in advanced disease.
Changmeng Zhang, Haoyun Li, Hongfei Wang, Liangyu Shi, Ying Shing Chan, Yu Wang, Graham Ka Hon Shea   +6 more
wiley   +1 more source