Results 191 to 200 of about 29,783 (293)

De Novo Multi‐Mechanism Antimicrobial Peptide Design via Multimodal Deep Learning

Advanced Science, EarlyView.
Current AI‐driven peptide discovery often overlooks complex structural data. This study presents M3‐CAD, a generative pipeline that leverages 3D voxel coloring and a massive database of over 12 000 peptides to capture nuanced physicochemical contexts.
Xiaojuan Li, Haifan Gong, Yue Wang, Yinuo Zhao, Lixiang Li, Peijing Bao, Qingzhou Kong, Jialu Fu, Boyao Wan, Yumeng Zhang, Jinghui Zhang, Jiekun Ni, Zhongxue Han, Xueping Nan, Kunping Ju, Longfei Sun, Yuerui Ma, Huijun Chang, Mengqi Zheng, Yanbo Yu, Xiaoyun Yang, Xiuli Zuo, Haina Wang, Yanqing Li   +23 more
wiley   +1 more source

Volcanoes stunt nearby glaciers. [PDF]

Nat Commun
Unnsteinsson T, Spagnolo M, Rea BR, Girona T, Barr I, Mullan D.   +5 more
europepmc   +1 more source

Connexin43 Deficiency Leads to Ventricular Arrhythmias by Reprogramming Proline Metabolism

Advanced Science, EarlyView.
The study demonstrated that connexin43 (Cx43) knockout caused arrhythmic phenotype and decreased proline content in vitro and in vivo. Mechanistically, Cx43 interacts with the amino acid transporter SNAT2 (sodium‐dependent neutral amino acid transporter), and its deficiency disrupts proline transport and metabolism.
Hangying Ying, Hangping Fan, Yunhe Wang, Ruhong Jiang, Dongsheng Cai, Hui Cheng, Hao Wang, Chenyang Jiang, Ping Liang   +8 more
wiley   +1 more source

A near real-time framework for monitoring very-long-period signals at volcanoes. [PDF]

Sci Rep
Gammaldi S, Donne DD, Cantiello P, Bobbio A, Caputo T, De Cesare W, Esposito AM, Peluso R, Orazi M.   +8 more
europepmc   +1 more source

Magnetic and electric field monitoring of Taal volcano, Philippines Part I: Magnetic measurements

, 2005
Makoto Harada, Julio P. Sabit, Yoichi Sasai, Paul Karson Alanis, Juan M. CORDON, E. Corpuz, J. Zlotnicki, Toshiyasu Nagao, Jane T. PUNONGBAYAN   +8 more
openalex   +2 more sources

miR‐185‐5p Derived From hUC‐MSC Exosomes via Suspension Culture Under Hypoxic Conditions Promotes Scarless Wound Healing in Mice by Precisely Regulating Collagen I/III Regeneration

Advanced Science, EarlyView.
miR‐185‐5p derived from UC‐MSC exosomes via hypoxic suspension culture promotes scarless wound healing in mice by precisely regulating collagen I/III regeneration. Exosomes derived from UC‐MSCs under a three‐dimensional bioreactor and hypoxic conditions were injected into the skin wounds of mice.
Lihua Yang, Yiqun Sun, Qinbiao Yan, Ali Mohsin, Kamran Ashraf, Senyi Gong, Weifeng Li, Touseef Ur Rehman, Yuwen Hu, Jinzhao He, Yu Liu, Meijun Ding, Lin Qi, Meijin Guo, Ke Xue   +14 more
wiley   +1 more source

Relationship Between Salivary Metabolites and Skeletal Muscle Index in Older Male Patients: A Retrospective Observational Pilot Study to Identify Potential Biomarkers. [PDF]

J Aging Res
Hayasaka T, Ishikawa S, Narisawa A, Moriya M, Toyama H, Sugimoto M.   +5 more
europepmc   +1 more source

Monitoring Techniques for Active Volcanoes

The Journal of the Petrological Society of Korea, 2014
Sung-Hyo Yun, Jeong-Hyun Lee, Cheol-Woo Chang   +2 more
openaire   +2 more sources

A New GNSS Campaign Network for Volcano Monitoring on Saba and St. Eustatius: Design, Initial Results, and Linking to Historical Data

Andreas Krietemeyer, Elske van Dalfsen
openalex   +1 more source

Targeting Peptostreptococcus anaerobius with an Iron‐Based Nanozyme Reverses Ferroptosis Resistance and Enhances Antitumor Immunity in Colorectal Cancer

Advanced Science, EarlyView.
An iron‐based nanozyme selectively eliminates intratumoral P. anaerobius while catalytically generating ROS to induce ferroptosis, synergistically suppressing colorectal cancer growth and activating anti‐tumor immunity through immunogenic cell death. ABSTRACT The intratumoral microbiota is a critical determinant of therapeutic outcomes in colorectal ...
Yinghao Cao, Jun Wang, Hanwenchen Wang, Xiang Sun, Fang Fang, Shiying Li, Jianping Liu, Changrong Shi, Pengyuan Qi, Jianhua Zou, Xiaoyuan Chen, Kailin Cai   +11 more
wiley   +1 more source