Results 211 to 220 of about 29,783 (293)

Peripheral blood immune cell subsets as non-invasive biomarkers of colorectal cancer stage, laterality, metastasis and survival. [PDF]

Cell Oncol (Dordr)
Del Prado-Montero J, Cantero-Cid R, Guevara-Martínez J, Lozano-Rodríguez R, Cueto FJ, Sáenz de Santa María-Diez G, Terrón-Arcos V, Abad-Moret R, Díaz-Serrano E, Córdoba-García L, Fernández-Felipe J, Montalbán-Hernández K, Del Fresno C, Hurtado-Navarro L, López-Collazo E.   +14 more
europepmc   +1 more source

Oral Streptococcus salivarius Couples Neutrophil IRGM1 Signaling to NET Formation and Colorectal Cancer Metastasis

Advanced Science, EarlyView.
The oral bacterium Streptococcus salivarius promotes colorectal cancer metastasis by inducing neutrophil extracellular trap (NET) formation. Mechanistically, IRGM1–IQGAP1 interaction activates Wnt5a–PI3K/AKT signaling in neutrophils, driving NET‐mediated tumor progression.
Fengyi Liu, Yuan Wang, Hengxuan Cai, Qianwen Yue, Xueli Liu, Xuanwen Bao, Zeng Wang, Xuehan Li, Lai Wei, Zhihua Zhang, Fan Xing, Yi Xu, Xianjun Li, Wei Xu   +13 more
wiley   +1 more source

Pu-erh tea attenuates obesity by remodeling gut microbiota and activating energy expenditure. [PDF]

Front Microbiol
Jiang X, Wu F, Xu M, Luo L, Zeng L.
europepmc   +1 more source

SLC2A3‐Mediated Lactate Metabolism Promotes Lung Cancer Bone Metastasis by Modulating P53 Lactylation and Immune Evasion

Advanced Science, EarlyView.
SLC2A3 derived lactate promotes metastasis through p53 lactylation at K120 and osteoclast differentiation. Pharmacological inhibition of SLC2A3 upregulates PD‐1 expression on CD8+ T cells via lactate induced p53 lactylation, which modulates immune evasion. ABSTRACT Bone metastasis is a devastating consequence of lung cancer.
Yi Ding, Yuying Tian, Wenjie Ren, Xianglin Hu, Mengjuan Li, Bei Liu, Chen chen, Yunhan Lu, Lei Li, Wangjun Yan, Kun Li   +10 more
wiley   +1 more source

Volcanic eruptions and the global subsea telecommunications network. [PDF]

Bull Volcanol
Clare MA, Yeo IA, Nash J, Hunt JE, Panuve S, Wilkie A, Williams R, Dowey N, Rowley P, Barclay J, Phillips J, Scarlett J, Engwell S, Henstock TJ, Seabrook S, Watson S, Wysoczanski R, Ribo M, Cronin S, Talling PJ, Cassidy M, Watt S, Robertson R.   +22 more
europepmc   +1 more source

Islet Amyloid Polypeptide Modelled to Simulate Diabetes Co‐Oligomerized with β‐Amyloid 1‐42 Reproducing the Pathological Cascade of Alzheimer's Disease in Human Cerebral Organoids

Advanced Science, EarlyView.
Human islet amyloid polypeptide (hIAPP) was used to mimic T2DM, and Aβ42‐hIAPP co‐oligomers were delivered into the human mature cerebral organoids (COs), which reproduce typical AD pathology and significant neuronal death more closely resembling that of AD patients.
Jin Yan, Zhimeng Tang, Yanyu Luo, Bin Liu, Xinxin Huang, Jun Wei, Feng Yue   +6 more
wiley   +1 more source

Volcanic eruptions and public health in Ecuador: an analysis of institutional gaps and integrated strategies. [PDF]

Front Public Health
Simbaña-Rivera K, Jaramillo-Aguilar DS, Guerrero-Gonzalez JP, Jimbo-Sotomayor R, Sánchez X, Mulas M, Boada LD.   +6 more
europepmc   +1 more source

On the importance of accounting for instrumental effects when applying gravimetry to volcano monitoring

Filippo Greco, Daniele Carbone, Danilo Contrafatto, A. Messina, Luca Mirabella   +4 more
openalex   +1 more source

β‐Adrenergic Signaling Promotes Anti‐Tumor Immunity in TP53‐mutant Oral Squamous Cell Carcinoma

Advanced Science, EarlyView.
β‐adrenergic stimulation enhances anti‐tumor immunity in TP53‐deficient oral squamous cell carcinoma by inducing tumor‐derived secretion of CXCL10, which attracts and activates cytotoxic CD8+ T cells. The findings demonstrate that β‐adrenergic signaling alters tumor–immune interactions via CXCL10‐mediated paracrine activation, revealing a neuro‐immune ...
Frederico O. Gleber‐Netto, Deborah Silverman, Tongxin Xie, Shamima Akhter, Nicole R. Vaughn, Adewale Adebayo, Kala Chand Debnath, Shorook Naara, Shajedul Islam, Erik Knutsen, Emily Lorin Ashkin, Simone Anfossi, Sara Leahey, Patrick Hwu, Sebastien Talbot, Erica K Sloan, Robert Saddawi‐Konefka, Roberto Rangel, Jeffrey N. Myers, George A. Calin, Moran Amit   +20 more
wiley   +1 more source

Urinary Proteomics as a Noninvasive Readout of Obesity-associated Inflammation. [PDF]

J Endocr Soc
Canki E, Kho E, van Stiphout R, Riksen NP, Netea M, Joosten LAB, Stienstra R, Hoenderop J.   +7 more
europepmc   +1 more source