Aged HSF1 muscle‐specific knockout mice show deteriorated muscle atrophy and metabolic dysfunction, while active HSF1 overexpression improves muscle function via activating SIRT3 to deacetylate both PGC1α1 and PGC1α4, which boosts mitochondrial function and muscle hypertrophy in a fiber‐type specific manner, and induces FNDC5/Irisin for tissue ...
Jun Zhang +18 more
wiley +1 more source
A near real-time framework for monitoring very-long-period signals at volcanoes. [PDF]
Gammaldi S +8 more
europepmc +1 more source
MODLEN: A semi-automated algorithm for monitoring small-scale thermal activity at Oldoinyo Lengai Volcano, Tanzania [PDF]
BELTON, F +5 more
core +1 more source
This study harnesses hydrodynamic flows to generate, confine and stimulate stem cell spheroids, enabling the large‐scale production of extracellular vesicles (EVs). This innovative method not only streamlines spheroid formation and subsequent EV release in a single, integrated process, but also ensures the generation of EVs with enhanced biological ...
Solène Lenoir +7 more
wiley +1 more source
Relationship Between Salivary Metabolites and Skeletal Muscle Index in Older Male Patients: A Retrospective Observational Pilot Study to Identify Potential Biomarkers. [PDF]
Hayasaka T +5 more
europepmc +1 more source
Remote Single-Station Seismic Monitoring of the July–October 2022 Earthquake Swarm at Ta‘ū Volcano, American Samoa [PDF]
Clara E. Yoon +14 more
openalex +1 more source
A Mussel‐Inspired Bioadhesive Patch to Selectively Kill Glioblastoma Cells
An innovative mussel‐inspired bioadhesive patch has been developed for post‐surgical glioblastoma treatment. The patch, which adheres strongly in biological environments, releases a localized treatment. This treatment, acting via reactive oxygen species, shows specific toxicity to glioblastoma cells.
Jose Bolaños‐Cardet +5 more
wiley +1 more source
Bryophyte Diversity in the Khaybar White Volcano Geopark (Saudi Arabia)-Floristic Patterns and Conservation Perspectives. [PDF]
Hugonnot V, Pépin F, Freedman J.
europepmc +1 more source
Magma migration beneath the active craters of Sakurajima volcano before the 2023 eruption of Showa crater inferred from ground deformation and muon monitoring [PDF]
L. Oláh +4 more
openalex +1 more source
Astrocytic PERK Deficiency Drives Prefrontal Circuit Dysfunction and Depressive‐Like Behaviors
Chen et al. show that the endoplasmic reticulum (ER) stress sensor PERK is downregulated in prefrontal cortex (PFC) astrocytes in major depressive disorder and in chronic‐stress mouse models. In young mice, astrocyte‐specific PERK loss reduces the synaptogenic cue thrombospondin‐1 (TSP1), leading to synaptic and circuit deficits and depressive‐like ...
Kai Chen +8 more
wiley +1 more source

