Results 261 to 270 of about 76,712 (329)

Urine Cell-Free RNA vs Plasma Cell-Free RNA for Monitoring of Kidney Injury and Immune Complications. [PDF]

Clin Chem
Mzava O, Agun GF, Loy CJ, Gonzalez-Bocco IH, Djomnang Kounatse LA, Bliss A, Wells SL, Lenz J, Belcher E, Chen K, Koo S, Baden LR, Chu T, Cheng MP, Ritz J, Gupta S, De Vlaminck I.   +16 more
europepmc   +1 more source

On the importance of accounting for instrumental effects when applying gravimetry to volcano monitoring

Filippo Greco, Daniele Carbone, Danilo Contrafatto, A. Messina, Luca Mirabella   +4 more
openalex   +1 more source

PBRM1 Deficiency Reshapes an Immune Suppressive Microenvironment Through Epigenetic Tuning of PBRM1‐KDM5C‐IL6 Axis in ccRCC

Advanced Science, EarlyView.
PBRM1 ranks as the second most commonly mutated gene in ccRCC. This study reveals that PBRM1 loss promotes an immunosuppressive microenvironment by elevating M2 TAMs via the KDM5C–IL‐6 axis. These M2 TAMs, along with CAFs, form a barrier that excludes CD8+ T cells. Targeting IL‐6 synergizes with anti‐PD1 therapy, offering a promising strategy for PBRM1‐
Wenjiao Xia, Hongru Wang, Yu Dong, Zitong Yang, Yiyang Zhou, Zhinan Xia, Qinchen Li, Liangliang Ren, Yichun Zheng, Junliang Yan, Dongmei Ma, Zhi Chen, Xingang Cui, Guixin Zhu, Cheng Zhang   +14 more
wiley   +1 more source

Dynamic astrocytic complement C3 activation in the epileptic hippocampus. [PDF]

Front Neurol
Jiang M, Romagnolo A, Aronica E, Wang Y.
europepmc   +1 more source

Disrupting the Formation of YAP Condensates Promotes the Activation of AMPKα to Inhibit the Progression of Primary Liver Cancer

Advanced Science, EarlyView.
This study systematically investigates the function and molecular mechanisms of YAP phase separation in multiple primary liver cancers. These findings provide novel insights into phase separation‐mediated primary liver cancer development and validate targeted disruption of this process as an effective therapeutic strategy for primary liver cancer ...
Shuang‐Zhou Peng, Jia‐Jia Liang, Yun‐Feng Zhan, Wei‐Xun Wu, Wan‐Li Xu, Xiao‐Kun Zhang, Li‐Jun Cai, Fu‐Quan Jiang   +7 more
wiley   +1 more source

The evolution of the 2022-2024 eruption at Home Reef, Tonga, analyzed from space shows vent migration due to erosion. [PDF]

Sci Rep
Plank S, Ciancia E, Genzano N, Falconieri A, Martinis S, Taubenböck H, Pergola N, Marchese F.   +7 more
europepmc   +1 more source

Unraveling the Morphological and Functional Maturation Mechanisms Underlying Human Neural Development Using iPSCs‐Derived Neuronal Model

Advanced Science, EarlyView.
Using human induced pluripotent stem cells (hiPSCs)‐derived neuronal model, Tian and colleagues reveal that voltage‐gated calcium channels Cav1.2 and Cav1.3, and their mediated calcium ion influx, are essential for early morphogenesis of human neuronal development, while ECEL1 underlies human neuronal functional developmental maturation through CALM3 ...
Yue Tian, Yi‐Chun Ou, Zi‐Xian Zhang, Jie Cai, Si‐Qing Cai, Guo‐Gang Xing   +5 more
wiley   +1 more source

Proteomics profiling of serum exosomes from azithromycin-sensitive and resistant <i>Mycoplasma pneumoniae</i>-infected patients reveals candidate biomarkers for diagnosis. [PDF]

Front Med (Lausanne)
Fan H, Huang F, Chen C, Ren Q, Zhou J, Yang D, Lu G.   +6 more
europepmc   +1 more source

Environmental Law at Maryland, no. 20, winter-spring 2005 [PDF]

, 2005

core   +1 more source

The Gut Microbiota Regulates Motor Deficits via Butyrate in a Gnal+/− Mouse Model of DYT25 Dystonia

Advanced Science, EarlyView.
The present study provides compelling evidence for a modulatory role of the gut microbiota in the pathology of DYT25 dystonia, and butyrate supplementation alleviates the motor deficits of dystonia in Gnal+/− mice. Abstract Dystonia is the third most common movement disorder, following essential tremor and Parkinson's disease. The underlying mechanisms
Jingya Guo, Seong‐Gook Kang, Kunlun Huang, Tao Tong   +3 more
wiley   +1 more source