Results 281 to 290 of about 76,712 (329)

Flipping the Switch: MeCP2‐Mediated Lactylation Rewires Microglial Metabolism and Inflammation via the HK2/mTOR Axis in Poststroke Neuroinflammation

Advanced Science, EarlyView.
Stroke‐induced lactate accumulation promotes p300‐mediated lactylation of methyl‐CpG binding protein 2 (MeCP2) at lysine 210, which reprograms microglial metabolism toward glycolysis and activates the hexokinase 2 (HK2)/mTOR axis. This cascade promotes proinflammatory responses and impairs neurofunctional outcomes.
Zengyu Zhang, Shanshan Huang, Yong Wang, Zhiwen Jiang, Zhuohang Liu, Chenran Wang, Rong Ji, Yiwen Yuan, Xueyu Mao, Kaicheng Yang, Huicong Niu, Yanqin Gao, Jing Zhao   +12 more
wiley   +1 more source

Soluble immune factor profiles in blood and CSF associated with LRRK2 mutations and Parkinson's disease. [PDF]

NPJ Parkinsons Dis
Jaffery R, Zhao Y, Ahmed S, Schumacher JG, Ahn J, Shi L, Wang Y, Tan Y, Zhang J, Chen K, Tawbi H, Wang J, Schwarzschild MA, Peng W, Chen X.   +14 more
europepmc   +1 more source

Indoor radon (222Rn) continuous monitoring in a building located at Furnas Volcano during 2017

, 2020
Silva, Catarina, Viveiros, Fátima
openalex   +1 more source

Nap1L4a Cooperates with Scl/Klf1 to Recruit H2A.Z in Mediating Interactions Among Cis‐Regulatory Elements and Transcription Required for Primitive Erythropoiesis in Zebrafish

Advanced Science, EarlyView.
Nap1l4a is required in erythropoiesis and hypoxia responses via physical interaction with Klf1 and Scl to recruit the histone variant H2A.Z. This facilitates its associated cis‐regulatory element (CRE) remodeling and the consequent chromatin assembly, and activates the transcription of erythroid lineage‐specific genes.
JiaHao Shi, FuMing Lai, Zheng Shen, XiaoYan Zhang, HanFei Wang, WenYe Liu, YunLong Wang, KuanYu Li, GuoLiang Li, YaPing Fang, Jing‐Xia Liu   +10 more
wiley   +1 more source

Decoding the saline-alkaline tolerance nexus in soybean: a dual-method evaluation model coupled with co-expression networks identifies core regulatory genes. [PDF]

Front Plant Sci
Fei L, Xionghui B, Mengjiao L, Aijing H, Baolong X.   +4 more
europepmc   +1 more source

2023 activity of Nyamulagira volcano monitored by SAR interferometric coherence

Marco Polcari, Emanuele Ferrentino, Charles M. Balagizi, Diego Coppola, Sébastien Valade   +4 more
openalex   +1 more source

Mapping the global health burden of volcanic exposure: a scoping review approach. [PDF]

Front Public Health
Simbaña-Rivera K, Endara-Mina J, Jaramillo-Aguilar DS, Mera-Lojano LD, Jimbo-Sotomayor R, Sánchez X, Rodríguez-Pérez MC, Fuentes-Ferrer ME, Boada LD.   +8 more
europepmc   +1 more source

Seismic array processing and computational infrastructure for improved monitoring of Alaskan and Aleutian seismicity and volcanoes

, 1998
Kent Lindquist
openalex   +1 more source

Magma chamber failure and dyke injection threshold for magma-driven unrest at Campi Flegrei caldera. [PDF]

Nat Commun
Natale J, Vitale S.
europepmc   +1 more source

Artistic and literary evidence of eruptive activity at Mt. Vesuvius during the apparent long quiescence period before the 1631 eruption. [PDF]

Sci Rep
Giudicepietro F, Calabria P, Cubellis E, Di Prisco C, Giacomelli L, Macedonio G, Martini C, Pappalardo L, Scandone R, Leone de Castris P.   +9 more
europepmc   +1 more source