CX3CL1 in Early Detection of Alzheimer's Disease: Plasma Dynamics Across Age and Disease Stages
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Backgrounds Alzheimer's disease (AD) is characterized by amyloid‐beta plaques, tau tangles, and neuroinflammation. C‐X3‐C motif chemokine ligand 1 (CX3CL1, also known as fractalkine), a neuroimmune chemokine implicated in AD pathogenesis, shows inconsistent alterations in plasma/serum across studies.
Ling Wang +6 more
wiley +1 more source
A Peridynamic Computational Scheme for Thermoelectric Fields. [PDF]
Materials (Basel), 2020 Zeleke MA, Xin L, Lisheng L.
europepmc +1 more source
NASA Low-Power Stirling Convertor for Small Landers, Probes, and Rovers Operating in Darkness [PDF]
A variety of mission concepts have been studied by NASA and the U. S. Department of Energy that would utilize low power Radioisotope Power Systems (RPS) for landers, probes, and rovers.
Casciani, Michael R. +5 more
core +1 more source
Value of MRI Outcomes for Preventive and Early‐Stage Trials in Spinocerebellar Ataxias 1 and 3
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective To examine the value of MRI outcomes as endpoints for preventive and early‐stage trials of two polyglutamine spinocerebellar ataxias (SCAs). Methods A cohort of 100 participants (23 SCA1, 63 SCA3, median Scale for the Assessment and Rating of Ataxia (SARA) score = 5, 42% preataxic, and 14 gene‐negative controls) was scanned at 3T up ...
Thiago J. R. Rezende +26 more
wiley +1 more source
New 5 Kilowatt Free-Piston Stirling Space Convertor Developments [PDF]
NASA has recently funded development of a 5 kW (or greater) free-piston Stirling conversion system for reactor power systems. A nominal 5 kW convertor allows two of these units to be dynamically balanced.
Brandhorst, Henry W.
core +1 more source
Complementarity of Long‐Reads and Optical Mapping in Parkinson's Disease for Structural Variants
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Long‐read sequencing and optical genome mapping technologies have the ability to detect large and complex structural variants. This has led to the discovery of novel pathogenic variants in neurodegenerative movement disorders. Thus, we aimed to systematically compare the SV detection capabilities of OGM and ONT in Parkinson's disease.
André Fienemann +17 more
wiley +1 more source
Triboelectric nanogenerators as wearable power sources and self-powered sensors. [PDF]
Natl Sci Rev, 2023 Pu X, Zhang C, Wang ZL.
europepmc +1 more source
Extended Operation Testing of Stirling Convertors in Support of Stirling Radioisotope Power System Development [PDF]
100 We class Stirling convertors began extended operation testing at NASA Glenn Research Center (GRC) in 2003 with a pair of Technology Demonstration Convertors (TDCs) operating in air.
Cornell, Peggy +5 more
core +2 more sources
Location‐Specific Hematoma Volume Predicts Early Neurological Deterioration in Supratentorial ICH
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Early neurological deterioration (END) adversely affects outcomes in patients with intracerebral hemorrhage (ICH). This study aimed to determine the location‐specific hematoma volumes for END in supratentorial ICH patients. Methods We retrospectively analyzed supratentorial ICH patients presenting from two prospective cohorts.
Zuoqiao Li +10 more
wiley +1 more source
A High-PSRR LDO with Low Noise and Ultra-Low Power Consumption. [PDF]
Micromachines (Basel)Guo N +5 more
europepmc +1 more source