Results 121 to 130 of about 3,195,442 (295)

Autophagy and mitophagy in pancreatic β‐cell homeostasis and their involvement in diabetes pathophysiology

open access: yesFEBS Letters, EarlyView.
This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee   +2 more
wiley   +1 more source

A new transformerless buck‐boost converter with improved voltage gain and continuous input current

open access: yesIET Power Electronics
This paper proposes a new transformerless buck‐boost converter with an extended voltage conversion ratio. This converter has semi‐quadratic voltage gain, which provides more gain with lower duty cycles.
Majid Hosseinpour   +3 more
doaj   +1 more source

Emerging experimental and computational methods for studying redox‐regulated structural transitions

open access: yesFEBS Letters, EarlyView.
Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass   +2 more
wiley   +1 more source

Energy optimization of multiprocessor systems on chip by voltage selection

open access: yes, 2007
Dynamic voltage selection and adaptive body biasing have been shown to reduce dynamic and leakage power consumption effectively. In this paper, we optimally solve the combined supply voltage and body bias selection problem for multiprocessor systems with
Eles, Petru Ion,   +9 more
core   +1 more source

Synergistic perspectives—How single‐molecule biophysics complement biochemical understanding

open access: yesFEBS Letters, EarlyView.
In this review, we discuss how ensemble biochemistry and single‐molecule approaches are complementary, outline commonly used single‐molecule techniques, and illustrate their relevance through two representative case studies: chromatin organization by SMC complexes and pathway choice during DNA double‐strand break repair.
Sara De Bragança   +2 more
wiley   +1 more source

A voltage reference using a temperature-dependent current to bias a junction diode [PDF]

open access: yes, 2013
textBandgap voltage-reference circuits generate an appropriate amount of a voltage that varies proportionately to absolute temperature (called PTAT), to cancel the complementary to absolute temperature voltage variation (known as CTAT) of a current ...
Mastovich, Stefan Noel
core  

Translophagy—A potential link between autophagy impairment and translational errors

open access: yesFEBS Letters, EarlyView.
Neurodegenerative diseases are characterised by the accumulation of abnormal proteins and protein aggregates, but their origin often remains unknown. We propose that selective autophagy removes damaged protein‐making machinery, preventing errors during protein synthesis.
Mykola V. Korolchuk   +11 more
wiley   +1 more source

Development of a Power Factor Corrected High Current Supercapacitor Charger for a Surge Resistant UPS [PDF]

open access: yes, 2012
The Uninterrupted Power Supplies (UPSs) provide short term power back up to electrical loads when the mains power fail. Usually UPSs employ battery packs as the energy storage device.
Zhang, Xu
core  

Co-Synthesis of Energy-Efficient Multi-Mode Embedded Systems with Consideration of Mode Execution Probabilities

open access: yes, 2005
We present a novel co-design methodology for the synthesis of energy-efficient embedded systems. In particular, we concentrate on distributed embedded systems that accommodate several different applications within a single device, i.e., multimode ...
Schmitz, M.T.   +5 more
core   +1 more source

VDGA-Based Resistorless Mixed-Mode Universal Filter and Dual-Mode Quadrature Oscillator

open access: yesApplied Sciences
This study introduces an electronically tunable resistorless mixed-mode universal filter and dual-mode quadrature oscillator configuration utilizing merely two voltage differencing gain amplifiers and two grounded capacitors.
Orapin Channumsin   +3 more
doaj   +1 more source

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