Results 101 to 110 of about 2,589,650 (335)

Intron‐oriented HTLV‐1 integration in an adult T‐cell leukemia/lymphoma cell line sustains expression of intact ift81 mRNA

open access: yesFEBS Letters, EarlyView.
In the adult T‐cell leukemia/lymphoma (ATL) cell line ED, the human T‐cell leukemia virus type 1 (HTLV‐1) provirus was integrated into the intron of the ift81 gene in the antisense orientation. Despite this integration, both the intact ift81 and the viral oncogene hbz were simultaneously expressed, likely due to the functional insufficiency of viral ...
Mayuko Yagi   +5 more
wiley   +1 more source

Positive dc to positive dc converter Patent [PDF]

open access: yes, 1969
Conversion of positive dc voltage to positive dc voltage of lower ...
Berry, E. H., Nola, F. J.
core   +1 more source

Cyclic nucleotide signaling as a drug target in retinitis pigmentosa

open access: yesFEBS Letters, EarlyView.
Disruptions in cGMP and cAMP signaling can contribute to retinal dysfunction and photoreceptor loss in retinitis pigmentosa. This perspective examines the mechanisms and evaluates emerging evidence on targeting these pathways as a potential therapeutic strategy to slow or prevent retinal degeneration.
Katri Vainionpää   +2 more
wiley   +1 more source

The epithelial barrier theory proposes a comprehensive explanation for the origins of allergic and other chronic noncommunicable diseases

open access: yesFEBS Letters, EarlyView.
Exposure to common noxious agents (1), including allergens, pollutants, and micro‐nanoplastics, can cause epithelial barrier damage (2) in our body's protective linings. This may trigger an immune response to our microbiome (3). The epithelial barrier theory explains how this process can lead to chronic noncommunicable diseases (4) affecting organs ...
Can Zeyneloglu   +17 more
wiley   +1 more source

Modeling and Simulation on the Hybrid Solution of Static Var Generator and Synchronous Condenser for Unlocking Power Output Limitation of Wind Farms Integrated into Weak Grid

open access: yesEnergies
The issues of low inertia, overvoltage, and wide-frequency oscillations in high-proportion renewable energy systems have become prominent, posing major challenges to renewable energy integration and threatening grid stability.
Haiyang Liang   +8 more
doaj   +1 more source

The Challenge of Voltage Channels

open access: yesJournal of the American College of Cardiology, 2014
We read with great interest the report by Mountantonakis et al. [(1)][1]. In this study, the authors reported that ventricular tachycardia (VT) isthmus sites were contained within channels in only 37% of voltage channels, and raised concerns about the suitability of using such channels as a ...
Pablo Ávila, Angel Arenal
openaire   +3 more sources

Goodbye flat lymphoma biology

open access: yesFEBS Letters, EarlyView.
Three‐dimensional (3D) biological systems have become key tools in lymphoma research, offering reliable in vitro and ex vivo platforms to explore pathogenesis and support precision medicine. This review highlights current 3D non‐Hodgkin lymphoma models, detailing their features, advantages, and limitations, and provides a broad perspective on future ...
Carla Faria   +3 more
wiley   +1 more source

From omics to AI—mapping the pathogenic pathways in type 2 diabetes

open access: yesFEBS Letters, EarlyView.
Integrating multi‐omics data with AI‐based modelling (unsupervised and supervised machine learning) identify optimal patient clusters, informing AI‐driven accurate risk stratification. Digital twins simulate individual trajectories in real time, guiding precision medicine by matching patients to targeted therapies.
Siobhán O'Sullivan   +2 more
wiley   +1 more source

Isolating switch state detection system based on depth information guidance

open access: yesElectronic Research Archive
This study addressed the critical role of isolating switches in controlling circuit connections for the stable operation of the substation. Our research introduced an innovative state detection system that utilized depth information guidance, comprising ...
Hui Xu   +5 more
doaj   +1 more source

Dynamic Voltage Scaling Aware Delay Fault Testing

open access: yes, 2006
The application of Dynamic Voltage Scaling (DVS) to reduce energy consumption may have a detrimental impact on the quality of manufacturing tests employed to detect permanent faults.
Al-Hashimi, Bashir M   +3 more
core  

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