Results 41 to 50 of about 1,327,278 (318)

European Standard Clinical Practice Guideline and EXPeRT Recommendations for the Diagnosis and Management of Gastroenteropancreatic Neuroendocrine Neoplasms in Children and Adolescents

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Pediatric gastroenteropancreatic neuroendocrine neoplasms (GEP‐NENs) are extremely rare and clinically heterogeneous. Management has largely been extrapolated from adult practice. This European Standard Clinical Practice Guideline (ESCP), developed by the EXPeRT network in collaboration with adult NEN experts, provides (adult) evidence ...
Michaela Kuhlen, Calogero Virgone, Antje Redlich, Michael Abele, Ricardo Lopez‐Almaraz, Tal Ben‐Ami, Ewa Bien, Gianni Bisogno, Maja Mazic Cesen, Andrea Ferrari, Malgorzata A. Krawczyk, Yves Reguerre, Dominik T. Schneider, Ines B. Brecht, Charlotte Rigaud, Bilgehan Yalcin, Rainer Claus, Christian Vokuhl, Constantin Lapa, Jörg Fuchs, Segolene Hescot, Thomas Walter, Julien Hadoux, Daniel Orbach   +23 more
wiley   +1 more source

Molecular mechanisms of the coupling of gating to voltage sensing in transmembrane proteins [PDF]

, 2014
Voltage gated potassium ion (Kv) channels regulate action potentials of the nervous system by responding to changes in transmembrane voltage, enabling K+ transport across the membrane to restore cells to their resting potential.
Starek, Greg
core   +1 more source

Health‐Related Quality of Life and Symptom Severity Among Patients With PIK3CA‐Related Overgrowth Spectrum: A Mixed‐Methods Study to Understand Real‐World Experience With Alpelisib Treatment

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background PIK3CA‐related overgrowth spectrum (PROS) includes several rare overgrowth disorders resulting from somatic gain‐of‐function mutations in PIK3CA. Despite treatment advances, including the recent approval of alpelisib for PROS in the United States, literature detailing the patient experience with PROS is limited.
Vamsi Bollu, Kaitlin LaGasse, Cory D. Saucier, Kimberly Raymond, Miranda Lauher‐Charest, Lauren Crowder, Beilei Cai, Mary Lisha Paul, Denise Adams   +8 more
wiley   +1 more source

Study of Transformer Core Vibration Considering Magnetostrictive Anisotropy

Active and Passive Electronic Components
Due to the influence of the magnetostrictive effect of silicon steel sheet, the core inevitably generates vibration in the working process of the transformer, and at the same time, there are differences in the magnetostrictive properties of silicon steel
Jian Zhang, Geqi Li, Yilin Wang, Yao Zhang   +3 more
doaj   +1 more source

Imaging Voltage in Neurons [PDF]

Neuron, 2011
In the last decades, imaging membrane potential has become a fruitful approach to study neural circuits, especially in invertebrate preparations with large, resilient neurons. At the same time, particularly in mammalian preparations, voltage imaging methods suffer from poor signal to noise and secondary side effects, and they fall short of providing ...
Peterka, Darcy, Takahashi, Hiroto, Yuste, Rafael   +2 more
openaire   +3 more sources

Clinical and Biological Features of Response in Resistant Neuroblastoma to 131I‐Metaiodobenzylguanidine Radiotherapy in the Anti‐GD2 Immunotherapy Era

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background 131I‐metaiodobenzylguanidine (131I‐MIBG) radiotherapy is a key treatment for relapsed and refractory (R/R) neuroblastoma (NB). Patients with R/R disease treated in the modern era are increasingly exposed to anti‐GD2 immunotherapy, which exerts selective pressure and may modify both tumor cell state and microenvironment.
Benjamin J. Lerman, Katherine K. Matthay, Fabienne Hollinger, Catriona Black, Ann A. Lazar, Miguel Pampaloni, Steven G. DuBois, Kieuhoa T. Vo   +7 more
wiley   +1 more source

Fault diagnosis method for high-voltage circuit breakers based on physics-informed transfer learning

Frontiers in Mechanical Engineering
IntroductionHigh-voltage circuit breakers are core control and protection equipment in power systems, and their operational status directly affects device stability and power grid security.
Dong Wang, Lubo Zhou, Liyun Xie, Xipu Liu, Shiqi Dong, Junhua Liu   +5 more
doaj   +1 more source

A Voltage Multiplier With Adaptive Threshold Voltage Compensation

IEEE Journal of Solid-State Circuits, 2017
A voltage multiplier (VM) with adaptive threshold voltage compensation is presented to enhance the power conversion efficiency (PCE). It is fabricated in a 0.18- $\mu \text{m}$ CMOS process. With the input frequency of 402 MHz and a load resistor of 30 $\text{k}\Omega $ , this VM achieves the PCE of 31.9% with the input power of −1 dBm, and ...
Ye-Sing Luo, Shen-Iuan Liu
openaire   +1 more source

KOHONEN NEURAL NETWORK CLUSTERING FOR VOLTAGE CONTROL IN POWER SYSTEMS [PDF]

, 2010
Clustering a power system is very useful for the purpose of voltage stability control. However, the methods have developed usually have computational inefficiency.
Nizam , Muhammad
core  

Hospitalization Through Families’ Eyes: Comparing Inpatient Care Quality for Children With Sickle Cell Disease and Cystic Fibrosis in Canada

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Sickle cell disease (SCD) is a chronic, inherited hemoglobinopathy that requires frequent hospitalization for disease‐related complications. Canadian data on inpatient care is limited. This study compared caregiver‐reported hospital experiences of children with SCD to those with cystic fibrosis (CF), a chronic, autosomal recessive ...
Hailey M. Zwicker, Kyle Kemp, Perri Tutelman, Sharon H. J. Hou, Paul Fairie, Maria Santana, Gregory M. T. Guilcher, Taryn Fay‐McClymont, Glenda Bendiak, Wendy Pelletier, Nicola Wright, Fiona Schulte   +11 more
wiley   +1 more source