Results 51 to 60 of about 20,714 (266)

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

FEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Voltage Self-Balancing Analysis of Indirect Series-Connected SiC MOSFETs for Electric Vehicle Fast Charging

Energies
Under the demand of electric vehicle DC fast-charging stations for medium-voltage DC–DC converters, the indirect series-connected hybrid clamped topology based on quasi-two-level (Q2L) modulation demonstrates significant application potential due to its ...
Qingliang Ma, Zhaoshui He, Yangjian Li, Junfeng Liu   +3 more
doaj   +1 more source

Diversity and complexity in neural organoids

FEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

Improved Control of Capacitor Voltage Balancing in Modular Multilevel Converter Submodules

IEEE Access
An improved incremental capacitor voltage balancing control strategy is proposed to solve the problems of large switching frequency, high complexity of the bubble method sorting algorithm, and exceeding the limit of the capacitor voltage fluctuation rate
Yanling Lyu, Yuansong Zi, Xiaowei Li
doaj   +1 more source

Linking neurogenesis, oligodendrogenesis, and myelination defects to neurodevelopmental disruption in primary mitochondrial disorders

FEBS Letters, EarlyView.
Mitochondrial remodeling shapes neural and glial lineage progression by matching metabolic supply with demand. Elevated OXPHOS supports differentiation and myelin formation, while myelin compaction lowers mitochondrial dependence, revealing mitochondria as key drivers of developmental energy adaptation.
Sahitya Ranjan Biswas, Porter L. Tomsick, Alicia M. Pickrell, Paul D. Morton   +3 more
wiley   +1 more source

Epigenetic blind spots – the role of DNA methylation dynamics in stem cell‐based models of embryogenesis

FEBS Letters, EarlyView.
Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil, Anna Corrà, Annalisa Scapolatiello, Chengxiang Qiu, Gianluca Amadei   +4 more
wiley   +1 more source

A Modular Cell Balancing Circuit and Strategy Based on Bidirectional Flyback Converter

Batteries
In this paper, a modular cell balancing circuit based on a bidirectional flyback converter (BFC) is designed, which is equipped with a symmetrical BFC for each cell.
Yipei Wang, Jun-Hyeong Kwon, Seong-Cheol Choi, Guangxu Zhou, Sung-Jun Park   +4 more
doaj   +1 more source

A SINGLE LC TANK BASED ACTIVE VOLTAGE BALANCING CIRCUIT FOR BATTERY MANAGEMENT SYSTEM

International Islamic University Malaysia Engineering Journal, 2018
A single series resonant converter has been designed to balance the voltage level of nowadays, battery operated vehicles and machine power tools are becoming popular due to their simple and compact structure, low operating and maintenance costs, moreover
AKM AHASAN HABIB, S.M.A Motakabber, MUHAMMAD IBN IBRAHIMY, AHM Zahirul Alam   +3 more
doaj   +1 more source

pH‐mediated activation of the lysosomal arginine sensor SLC38A9

FEBS Letters, EarlyView.
Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley   +1 more source

A Novel Low-Power Bipolar DC–DC Converter with Voltage Self-Balancing

Journal of Low Power Electronics and Applications
Bipolar power supply can effectively reduce line losses and optimize power transmission. This paper proposes a low-power bipolar DC–DC converter with voltage self-balancing, which not only achieves bipolar output but also automatically balances the inter-
Yangfan Liu, Qixiao Li, Zhongxuan Wang
doaj   +1 more source