Results 31 to 40 of about 20,529 (264)

Emerging experimental and computational methods for studying redox‐regulated structural transitions

FEBS Letters, EarlyView.
Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass, Dana Reichmann, Gábor Erdős   +2 more
wiley   +1 more source

Self-Powered Electrochemical Lactate Biosensing

Energies, 2017
This work presents the development and characterization of a self-powered electrochemical lactate biosensor for real-time monitoring of lactic acid. The bioanode and biocathode were modified with D-lactate dehydrogenase (D-LDH) and bilirubin oxidase (BOD)
Ankit Baingane, Gymama Slaughter
doaj   +1 more source

Mitochondrial translation and coordinated cytosolic translation in metabolic homeostasis and disease

FEBS Letters, EarlyView.
Mitochondrial function depends on coordinated protein production from the nuclear and mitochondrial genomes. This review highlights how cytosolic and mitochondrial translation, mRNA localization, protein import, and respiratory complex assembly are integrated to maintain mitochondrial proteostasis and function.
Boseon Kim, Thi Thanh Mai Tran, Nakyung Kang, Min‐Woo Lee, Mihye Lee   +4 more
wiley   +1 more source

Development and Control of a Switched Capacitor Multilevel Inverter

Energies, 2023
This article offers a novel boost inverter construction with a Nine-level quadruple voltage boosting waveform. The primary drawback of conventional MLI is the need for a high voltage DC-DC converter to increase the voltage when using renewable energy ...
Safwan Mustafa, Adil Sarwar, Mohd Tariq, Shafiq Ahmad, Haitham A. Mahmoud   +4 more
doaj   +1 more source

Mutant p53R273H disrupts PDPK1 homodimerization and contributes to PDPK1 activation

Molecular Oncology, EarlyView.
How mutant p53R273H drives AKT signaling is unclear. We show that p53R273H, but not wild‐type, directly binds PDPK1 via a mutation‐dependent conformational change. This interaction disrupts inhibitory PDPK1 homodimerization and enhances AKT phosphorylation.
Mei Chee Lim, Alvin Kunyao Guo, Yoko Itahana, Srinivasaraghavan Kannan, Valerie Goh, Mingmin Ong, Terina Yan Wen Tay, Weiying Ye, Sabhashina Radha Krishnan, Jun Nishiyama, Chandra S Verma, Koji Itahana   +11 more
wiley   +1 more source

Switched Capacitor Based High Step-Up Multilevel Inverter with Self-Balancing Ability and Low Switching Stress

International Transactions on Electrical Energy Systems, 2022
In this article, the switched capacitor (SC) based high step-up multilevel inverter is proposed with self-balancing capability. The proposed SC inverter topology is to step up the high output voltage from the very low input voltage without any bulky ...
M. Venkatesan, S. Gouse Basha, A. Ramkumar, R. Manikandan, M. Easwaran, Baseem Khan   +5 more
doaj   +1 more source

The impact of leukocyte‐associated RNA retention on platelet RNA‐based cancer detection

Molecular Oncology, EarlyView.
Platelets carry RNA signals that may help detect cancer, but platelet samples can also retain RNA from white blood cells. We found that this retained white blood cell signal did not significantly affect machine learning cancer classification, suggesting that the cancer‐related RNA signal in platelets is largely independent of leukocyte‐associated RNA ...
Michał Sieczczyński, Krzysztof Pastuszak, Anna Samelak‐Czajka, Zuzanna Cemka, Paulina Jackowiak, Tomasz Stefaniak, Sylwia Łapińska‐Szumczyk, Jacek Jassem, Anna J. Żaczek, Matthew T. Rondina, Myron G. Best, Sjors G. J. G. In 't Veld, Anna Supernat   +12 more
wiley   +1 more source

Lower Energy Storage-Based 9L- Switched Capacitor ANPC Inverter Topology With Voltage Boosting Features

IEEE Access
This article proposes a novel 9L-switched capacitor inverter circuit with a voltage-boosting feature. The presented circuit uses fewer energy-stored capacitors, which reduces the size and cost.
R. Sekar, M. Jagabar Sathik, Mamdouh L. Alghaythi, Meshari S. Alshammari, K. Vijayakumar   +4 more
doaj   +1 more source

UiO‐66 metal–organic frameworks in biomedicine: From structural tunability to bioimaging, photodiagnostics, and photodynamic cancer therapy

FEBS Open Bio, EarlyView.
UiO‐66(Zr) metal–organic frameworks are chemically stable, biocompatible, and highly tunable nanomaterials. Their modular structure enables controlled drug delivery, multimodal bioimaging, and light‐activated photodynamic therapy, supporting integrated diagnostic and therapeutic (theranostic) applications in cancer and biomedical research.
Veronika Huntošová, Grigorii Rakhalskii, Miroslav Almáši   +2 more
wiley   +1 more source

Modeling and Control of a Voltage-Lift Cell Split-Source Inverter With MPPT for Photovoltaic Systems

IEEE Access, 2023
In this study, a new single-stage inverter with improved boosting performance was proposed to enhance the recently developed split-source inverter (SSI) topology. The study introduced new SSI configurations with high voltage gain.
Mostafa Wageh Lotfy, Sherif M. Dabour, Ramadan Mahmoud Mostafa, Dhafer J. Almakhles, Mahmoud F. Elmorshedy   +4 more
doaj   +1 more source