Results 171 to 180 of about 636,624 (317)

The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers

open access: yesMolecular Oncology, EarlyView.
The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce   +11 more
wiley   +1 more source

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

open access: yesMolecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat   +8 more
wiley   +1 more source

Estimation of voltage variation events with adaptive linear filtering

open access: yes, 2014
[[abstract]]In recent years, with the booming of high-tech industry, there are many high-precision power electronic equipment being used. Most of them can not afford the transient changes in electricity.
Chen, Cheng-I;Chen, Cheng-I;Ch, Chieh-Yin;Cheng, Chieh-Yin;陳永欽;CHEN, YEONG-CHIN;*   +1 more
core  

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

open access: yesMolecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Investigating low voltage ride through capability on wind farm by using static synchronus compensator (STATCOM) application

open access: yes, 2012
As an alternative to traditional fossil fuel extracted energy, wind energy has been acknowledged as one of the most important sources of renewable energies in the world.
Forest, Zack
core  

Circular RNA expression landscapes in myelodysplastic neoplasms: Associations with mutational signatures and disease progression

open access: yesMolecular Oncology, EarlyView.
In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge   +17 more
wiley   +1 more source

Robust direct voltage control of stand-alone DFIG wind systems using a fractional-order fuzzy logic approach. [PDF]

open access: yesSci Rep
Boucetta F   +7 more
europepmc   +1 more source

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