Results 101 to 110 of about 200,324 (298)

Enteropathogenic E. coli shows delayed attachment and host response in human jejunum organoid‐derived monolayers compared to HeLa cells

FEBS Letters, EarlyView.
Enteropathogenic E. coli (EPEC) infects the human intestinal epithelium, resulting in severe illness and diarrhoea. In this study, we compared the infection of cancer‐derived cell lines with human organoid‐derived models of the small intestine. We observed a delayed in attachment, inflammation and cell death on primary cells, indicating that host ...
Mastura Neyazi, Pilar Samperio Ventayol, Natalie Burkard, Nicolas Schlegel, Carmen Aguilar, Sina Bartfeld   +5 more
wiley   +1 more source

Organoids in pediatric cancer research

FEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

Study on the Impact of Aviation Electrification on Voltage Deviation of the GB Transmission System

, 2022
With the increasing demand for clean energy and rapid development of battery technology, there has been a notable trend in developing aviation electrification, particularly for small or regional electric aircraft (EA).
Zhang, Xin, Yuan, Yuejie, Li, Bozheng, Guo, Zekun   +3 more
core   +1 more source

A Novel Meta-Heuristic Optimization Algorithm to Determine Optimal Access Point and Generation of Distributed Generators for Maximizing Economic and Technical Benefits [PDF]

Iranian Journal of Electrical and Electronic Engineering
This paper presents an intelligent meta-heuristic algorithm, named improved equilibrium optimizer (IEO), for addressing the optimization problem of multi-objective simultaneous integration of distributed generators at unity and optimal power factor in a ...
Nguyen Cong Chinh
doaj  

Multi-time Scale Voltage-Reactive Power Control for Distribution Network with Distributed Generation

Journal of Harbin University of Science and Technology
Aiming at the problems of network loss increase, voltage deviation and voltage exceeding specified limits when large- scale distributed generations ( DGs) connected to distribution network ( DN) , this paper proposes a multi-time scale coordinated ...
LIU Haotian, ZHENG Chuyu, LENG Yang, LI Qin, ZHANG Hua, CHEN Shidu, LI Jiayong   +6 more
doaj   +1 more source

Reciprocal control of viral infection and phosphoinositide dynamics

FEBS Letters, EarlyView.
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley   +1 more source

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

FEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho, Shin Morioka, Junko Sasaki, Takehiko Sasaki   +3 more
wiley   +1 more source

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

FEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes, Guilherme M. Azevedo, Amanda P. Barcellos, Diana Bahia   +3 more
wiley   +1 more source

A Bi-Level Optimization Scheme for Energy Storage Configuration in High PV-Penetrated Distribution Networks Based on Improved Voltage Sensitivity Strategy

Energies
This study proposes a bi-level optimization strategy to determine the optimal location and capacity for energy storage systems. Before applying the proposed bi-level optimization scheme, the PV output data are clustered by the K-means algorithm, and an ...
Bo Gao, Qing Du, Gonghao Zhan, Jian Han
doaj   +1 more source

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

FEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe, Tanmay Kumar Mohanty, Rashna Bhandari, Dorothea Fiedler   +3 more
wiley   +1 more source