Results 251 to 260 of about 200,324 (298)

Proteasome inhibitor, ixazomib prevents topoisomerase‐I degradation and reverses irinotecan resistance in colorectal cancer

Molecular Oncology, EarlyView.
Ixazomib inhibits proteasome‐mediated degradation of topoisomerase I induced by irinotecan, thereby restoring drug sensitivity and promoting tumor cell death in colorectal cancer. Irinotecan, a topoisomerase I (topoI) inhibitor, is widely used for colorectal cancer, but resistance remains a major clinical challenge.
Yuho Ebata, Koji Ando, Hirofumi Hasuda, Koshi Mimori, Elizabeth C. Unan, Siddhartha Pulukuri, Aahana Tiku, Allison Berger, Eiji Oki, Ajit Bharti, Tomoharu Yoshizumi   +10 more
wiley   +1 more source

Collaborative Operation Optimization of a Hybrid Electrolyzer Fleet for an Integrated Wind-Solar-to-Ammonia System. [PDF]

ACS Omega
Meng T, Piao Z, Liu H.
europepmc   +1 more source

Metastasis on pause: How dormant tumor cells stay hidden within the tumor microenvironment and evade immune surveillance

Molecular Oncology, EarlyView.
Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary, Jose Javier Bravo‐Cordero   +1 more
wiley   +1 more source

A Comparison of Cost-Effective Sensors for a Fluorescence-Based Detection System Used in Biodiagnostic Devices. [PDF]

Biosensors (Basel)
Vornweg R, Decool C, Hemmer M, Stollfuss B, Guenther T, Löffler AK, Kontermann RE, Zimmermann A.   +7 more
europepmc   +1 more source

DNA methylation and expression of MAPRE3 affect overall survival of early‐stage non‐small cell lung cancer patients

Molecular Oncology, EarlyView.
Both cg12821679MAPRE3 methylation and MAPRE3 expression are significantly associated with overall survival (OS) of non‐small cell lung cancer. Meanwhile, MAPRE3 expression significantly modified the effect of smoking cessation on OS. Smoking cessation benefits OS merely for patients with high MAPRE3 expression.
Chao Chen, Jiancheng Cheng, Ruili Hou, Xiaoyuan Zheng, Li Su, Maria Moksnes Bjaanæs, Anna Karlsson, Maria Planck, Johan Staaf, Åslaug Helland, Manel Esteller, David C. Christiani, Feng Chen, Xiaofei Cao, Ruyang Zhang   +14 more
wiley   +1 more source

Experimental Characterization and Calibration of a MEMS Electric Field Sensor Under DC Ionized Field Conditions. [PDF]

Micromachines (Basel)
Ren R, Li B, Peng C.
europepmc   +1 more source

EVA-centric QUBO optimization for active and reactive power coordination in DLMP-driven distribution systems. [PDF]

Sci Rep
Suri V, Nagpal N, Siano P, Sharma R, Agarwal S, Pak W.   +5 more
europepmc   +1 more source

Multi-timescale energy-aware grid-forming control with self-tuning virtual inductance for battery lifetime enhancement. [PDF]

Sci Rep
Zheng L, Liu X.
europepmc   +1 more source

Probabilistic OPF and LFC of conventional with RES, energy storage and FACTS using DTBO. [PDF]

Sci Rep
Roy A, Dutta S, Biswas S, Bhattacharya A, Ghosh S, Banerjee S.   +5 more
europepmc   +1 more source

Machine learning-driven renewable energy grid integration stability assessment: LIME interpretability and LLM intelligent analysis. [PDF]

Sci Rep
Xu R, Zheng Y, Meng Q, Yang Q.
europepmc   +1 more source