Effect of chemotherapy on passenger mutations in metastatic colorectal cancer
Changes in passenger mutation load and predicted immunotherapy response after chemotherapy treatment. Tumor cells rich with passenger mutations have increased sensitivity to chemotherapy. Correlation of passenger mutations with neoantigen load suggests highly mutated clones promote a more effective response to immunotherapy, and therefore, first‐line ...
Marium T. Siddiqui +6 more
wiley +1 more source
Quantifying and mitigating electrical and environmental impacts of corona discharge. [PDF]
Zobaa AM +3 more
europepmc +1 more source
Dual targeting of RET and SRC synergizes in RET fusion‐positive cancer cells
Despite the strong activity of selective RET tyrosine kinase inhibitors (TKIs), resistance of RET fusion‐positive (RET+) lung cancer and thyroid cancer frequently occurs and is mainly driven by RET‐independent bypass mechanisms. Son et al. show that SRC TKIs significantly inhibit PAK and AKT survival signaling and enhance the efficacy of RET TKIs in ...
Juhyeon Son +13 more
wiley +1 more source
Balancing Cost and Precision: An Experimental Evaluation of Sensors for Monitoring in Electrical Generation Systems. [PDF]
Alcalá J +5 more
europepmc +1 more source
Generation of two normal and tumour (cancerous) paired human cell lines using an established tissue culture technique and their characterisation is described. Cell lines were characterised at cellular, protein, chromosome and gene expression levels and for HPV status.
Simon Broad +12 more
wiley +1 more source
Location allocation and capacity optimization for a PV and battery integrated hybrid community electric vehicle charging station. [PDF]
Kayal P, Braciník P.
europepmc +1 more source
Portable Multichannel Measurement System for Real-Time Microplastics Assessment Using Microwave Sensors. [PDF]
Barrancos A +3 more
europepmc +1 more source
Adaptive virtual impedance control strategy based on IWOA-fuzzy PID and its application to reactive power sharing in islanded microgrids. [PDF]
Hou Y.
europepmc +1 more source

