Results 111 to 120 of about 3,331,678 (298)

Autophagy and mitophagy in pancreatic β‐cell homeostasis and their involvement in diabetes pathophysiology

open access: yesFEBS Letters, EarlyView.
This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee   +2 more
wiley   +1 more source

Remote Low-Cost Differential Isolated Probe for Voltage Measurements

open access: yesApplied Sciences
The growing development of communication technologies has given rise to the Internet of Things, which has led to the emergence of new cities, smart grids, and smart buildings, and the development of energy generation using renewable sources, as well as ...
Diego Antolín-Cañada   +4 more
doaj   +1 more source

Golgi enzymes are retrieved from the plasma membrane to the trans‐Golgi network

open access: yesFEBS Letters, EarlyView.
Golgi enzymes are traditionally considered resident proteins retained within the Golgi apparatus. Here, we demonstrate that a subset transiently reaches the cell surface and is subsequently retrieved to the trans‐Golgi network via retrograde transport. Using a nanobody‐based toolkit, we uncover a dynamic trafficking cycle of several Golgi enzymes.
Dominik P. Buser, Tina Junne
wiley   +1 more source

Emerging experimental and computational methods for studying redox‐regulated structural transitions

open access: yesFEBS Letters, EarlyView.
Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass   +2 more
wiley   +1 more source

Space charge measurement and analysis in low density polyethylene films

open access: yes, 2009
The growing requirement of reliability for an insulation system gives researchers greater responsibility to investigate new techniques for monitoring and diagnosing dielectrics subjected to an electric field.
Xu, Zhiqiang
core   +1 more source

Grounding Analysis of Noncontact Three-Phase Voltage Measurement

open access: yesIEEE Access
This paper analyzes how power system grounding impacts capacitive noncontact three-phase ac voltage measurement of multi-wire cables. Experimental results with new sensing hardware verify the analysis.
Thomas C. Krause   +3 more
doaj   +1 more source

HIFU Power Monitoring Using Combined Instantaneous Current and Voltage Measurement. [PDF]

open access: yesIEEE Trans Ultrason Ferroelectr Freq Control, 2020
Adams C   +3 more
europepmc   +1 more source

Synergistic perspectives—How single‐molecule biophysics complement biochemical understanding

open access: yesFEBS Letters, EarlyView.
In this review, we discuss how ensemble biochemistry and single‐molecule approaches are complementary, outline commonly used single‐molecule techniques, and illustrate their relevance through two representative case studies: chromatin organization by SMC complexes and pathway choice during DNA double‐strand break repair.
Sara De Bragança   +2 more
wiley   +1 more source

Translophagy—A potential link between autophagy impairment and translational errors

open access: yesFEBS Letters, EarlyView.
Neurodegenerative diseases are characterised by the accumulation of abnormal proteins and protein aggregates, but their origin often remains unknown. We propose that selective autophagy removes damaged protein‐making machinery, preventing errors during protein synthesis.
Mykola V. Korolchuk   +11 more
wiley   +1 more source

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