Results 71 to 80 of about 219,076 (264)

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

open access: yesFEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa   +2 more
wiley   +1 more source

Phosphoinositides and inositol phosphates as molecular glues

open access: yesFEBS Letters, EarlyView.
Inositol phosphates (IPs) and phosphoinositides (PIPs) regulate diverse eukaryotic processes. Beyond recruiting signaling proteins or acting as structural cofactors, recent studies suggest they mediate protein–protein interactions as natural molecular glues.
Aleshia Seaton‐Terry   +9 more
wiley   +1 more source

Robust AC Voltage Regulation of Microgrids in Islanded Mode with Sinusoidal Internal Model

open access: yesSICE Journal of Control, Measurement, and System Integration, 2017
This paper shows that the H∞ control is an effective tool for electric voltage regulation. We here consider robust AC voltage regulation of microgrids in an islanded mode.
Naoki Hayashi   +2 more
doaj   +1 more source

Robust voltage‐mode controller for DC–DC boost converter

open access: yesIET Power Electronics, 2015
In this study, a robust voltage‐mode controller for DC–DC boost converter subject to time varying parameters is presented. The time‐varying parameters of the boost converter are considered as the input voltage, the load resistance and the passive components (inductor and capacitor).
Sakarya Üniversitesi/Mühendislik Fakültesi/Elektrik-Elektronik Mühendisliği Bölümü   +2 more
openaire   +1 more source

Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis

open access: yesFEBS Letters, EarlyView.
Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee   +7 more
wiley   +1 more source

Three-Bridge LLC Resonant Converter with 5 Operation Mode Transitions for Wide Output Voltage Control

open access: yesEnergies
This paper presents a 3-Bridge LLC resonant converter featuring wide output voltage gain characteristics and a novel control method. To achieve operation within a narrower frequency control range, the proposed converter introduces one additional ...
Jin-woo Kim   +6 more
doaj   +1 more source

α‐Synuclein aggregation landscape from phase separation to neurotoxic intermediates

open access: yesFEBS Letters, EarlyView.
Alpha‐synuclein aggregation in Parkinson's disease involves a complex landscape of transient intermediates, including oligomers, fibrils and liquid–liquid phase separation (LLPS). A view is emerging in which LLPS maturation into solid‐like condensates may contribute to the formation of neurotoxic species.
Silvia Arino   +2 more
wiley   +1 more source

Three phosphatase families form a community: The phosphohydrolases that act upon inositol pyrophosphates

open access: yesFEBS Letters, EarlyView.
Inositol pyrophosphates are energy‐rich signaling molecules that perform critical functions in cells. Three different families of phosphatases hydrolyze the β phosphate of the inositol pyrophosphate molecules: two have narrow specificities and one is promiscuous.
Ronda J. Rolfes
wiley   +1 more source

Autonomous Control Strategy of DC Microgrid for Islanding Mode Using Power Line Communication

open access: yesEnergies, 2018
This paper proposes a DC-bus signaling (DBS) method for autonomous power management in a DC microgrid, used to improve its reliability. Centralized power management systems require communication between the power sources and loads.
Dong-Keun Jeong   +4 more
doaj   +1 more source

Modelling stem cell differentiation related processes—A practical overview for biologists

open access: yesFEBS Letters, EarlyView.
Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar   +4 more
wiley   +1 more source

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