Results 51 to 60 of about 61,828 (303)

Modeling hepatic fibrosis in TP53 knockout iPSC‐derived human liver organoids

Molecular Oncology, EarlyView.
This study developed iPSC‐derived human liver organoids with TP53 gene knockout to model human liver fibrosis. These organoids showed elevated myofibroblast activation, early disease markers, and advanced fibrotic hallmarks. The use of profibrotic differentiation medium further amplified the fibrotic signature seen in the organoids.
Mustafa Karabicici, Soheil Akbari, Ceyda Caliskan, Canan Celiker, Ozden Oz, Leman Binokay, Gökhan Karakulah, Serif Senturk, Esra Erdal   +8 more
wiley   +1 more source

An Interleaved Buck-Boost-Zeta Converter With Coupled Inductor Multiplier Cell and Zero Input Current Ripple for High Step-Up Applications

IEEE Access
An interleaved Buck-Boost-Zeta converter with the coupled inductor multiplier cell and zero input current ripple is proposed in this paper, which is suitable for high step-up applications such as the photovoltaic generation system.
Ying He, Liang Chen, Xuanjin Sun
doaj   +1 more source

Time-division-multiplex control scheme for voltage multiplier rectifiers

The Journal of Engineering, 2017
A voltage multiplier rectifier with a novel time-division-multiplexing (TDM) control scheme for high step-up converters is proposed in this study. In the proposed TDM control scheme, two full-wave voltage doubler rectifiers can be combined to realise a ...
Bin-Han Liu, Jen-Hao Teng, Wei-Lun Tsai
doaj   +1 more source

Controllable high voltage source having fast settling time [PDF]

, 1975
A high voltage dc stepping power supply for sampling a utilization device such as an electrostatic analyzer has a relatively fast settling time for voltage steps. The supply includes a waveform generator for deriving a low voltage staircase waveform that
Acuna, M. H., Doong, H.
core   +1 more source

Generalised Cockcroft-Walton voltage multipliers

Electronics Letters, 1973
The letter suggests how a Cockroft-Walton voltage multiplier can be generalised to be driven by multiphase square waves.
openaire   +1 more source

Programmable voltage multiplier for pacemaker outputpulse generation

Electronics Letters, 1999
The problems that arise when trying to port pacemaker analogue blocks to submicrometre technology are discussed. A circuit topology is proposed for a programmable voltage multiplier that can handle the relatively high voltages required to stimulate the heart, while still being able to operate from an almost exhausted pacemaker battery.
NOVO A, GEROSA, ANDREA, NEVIANI, ANDREA, MOZZI A, ZANONI, ENRICO   +4 more
openaire   +1 more source

Aggressive prostate cancer is associated with pericyte dysfunction

Molecular Oncology, EarlyView.
Tumor‐produced TGF‐β drives pericyte dysfunction in prostate cancer. This dysfunction is characterized by downregulation of some canonical pericyte markers (i.e., DES, CSPG4, and ACTA2) while maintaining the expression of others (i.e., PDGFRB, NOTCH3, and RGS5).
Anabel Martinez‐Romero, Ane Martinez‐Larrinaga, Joaquim Grego‐Bessa, Saioa Garcia‐Longarte, Hielke van Splunder, Ianire Astobiza, Amaia Ercilla, Laura Bozal‐Basterra, Isabel Mendizabal, Pilar Villacampa, Arkaitz Carracedo, Mariona Graupera   +11 more
wiley   +1 more source

Arc lamp power supply using a voltage multiplier [PDF]

, 1988
A power supply is provided for an arc discharge lamp which includes a relatively low voltage high current power supply section and a high voltage starter circuit.
Leighty, Bradley D.
core   +1 more source

High‐voltage‐gain quadratic boost converter with voltage multiplier

IET Power Electronics, 2015
In this study, a novel high‐gain quadratic boost converter with a voltage multiplier circuit is presented to give an alternative power electronic circuit for high‐voltage conversion and low‐to‐medium power applications. The proposed converter combines the traditional quadratic boost converter and a coupled‐inductor‐based voltage multiplier circuit ...
Zhang, Neng, Sutanto, Danny, Muttaqi, Kashem M, Zhang, Bo, Qiu, Dongyuan   +4 more
openaire   +2 more sources

Glycosylated LGALS3BP is highly secreted by bladder cancer cells and represents a novel urinary disease biomarker

Molecular Oncology, EarlyView.
Urinary LGALS3BP is elevated in bladder cancer patients compared to healthy controls as detected by the 1959 antibody–based ELISA. The antibody shows enhanced reactivity to the high‐mannose glycosylated variant secreted by cancer cells treated with kifunensine (KIF).
Asia Pece, Giulio Lovato, Ilaria Cela, Arianna Mercatelli, Benedetta Ferro, Jussi Nikkola, Sara Pagotto, Tommaso Grottola, Vincenzo De Laurenzi, Rossella Cicchetti, Antonio Marchetti, Luigi Schips, Rossano Lattanzio, Stefano Iacobelli, Emily Capone, Peter Black, Mads Daugaard, Michele Marchioni, Gianluca Sala   +18 more
wiley   +1 more source