Results 71 to 80 of about 61,828 (303)

Derivation of a tangent function using an integrated circuit four-quadrant multiplier [PDF]

open access: yes, 1973
A tangent function generator is provided which utilizes input signals proportionate to the sine and cosine of a given angle. The equipment accomplishes a trigonometric manipulation which forms an output signal substantially independent of the input ...
Bregman, B. J.
core   +1 more source

Genetic attenuation of ALDH1A1 increases metastatic potential and aggressiveness in colorectal cancer

open access: yesMolecular Oncology, EarlyView.
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova   +25 more
wiley   +1 more source

Targeted modulation of IGFL2‐AS1 reveals its translational potential in cervical adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
Cervical adenocarcinoma patients face worse outcomes than squamous cell carcinoma counterparts despite similar treatment. The identification of IGFL2‐AS1's differential expression provides a molecular basis for distinguishing these histotypes, paving the way for personalized therapies and improved survival in vulnerable populations globally.
Ricardo Cesar Cintra   +6 more
wiley   +1 more source

Hands‐on protocol for preparing water‐soluble fractions from agri‐food samples for NMR‐based metabolomics analysis

open access: yesFEBS Open Bio, EarlyView.
This research protocol outlines a workflow for nuclear magnetic resonance (NMR)‐based metabolomics in the agri‐food sector. Using two case studies—strawberry leaves (solid matrix) and wine (liquid matrix)—it details the procedures for sample preparation, data acquisition, and processing.
Andrea Fernández‐Veloso   +4 more
wiley   +1 more source

Antibiofilm activity of a chionodracine‐derived peptide by NMR‐based metabolomics of cell‐free supernatant of Acinetobacter baumannii clinical strains

open access: yesFEBS Open Bio, EarlyView.
KHS‐Cnd peptide is able to impair biofilm formation and disaggregate mature biofilms in Acinetobacter baumannii clinical isolates. Differences in extracellular metabolites reflect changes in biofilm metabolism due to KHS‐Cnd treatment. Among the differentially represented extracellular metabolites upon KHS‐Cnd treatment, the significantly altered ...
Fernando Porcelli   +9 more
wiley   +1 more source

Lower-Order Compensation Chain Threshold-Reduction Technique for Multi-Stage Voltage Multipliers

open access: yesSensors, 2018
This paper presents a novel threshold-compensation technique for multi-stage voltage multipliers employed in low power applications such as passive and autonomous wireless sensing nodes (WSNs) powered by energy harvesters.
Francesco Dell’ Anna   +6 more
doaj   +1 more source

Low Voltage PV Interface to a High Voltage Input Source with Modified RVMR

open access: yesAdvances in Electrical and Computer Engineering, 2022
In this work PV fed Modified Resonant Voltage Multiplier Rectifier (RVMR) has been proposed for the hybrid renewable energy system. PV source energy is maximized in the modified RVMR scheme by applying the perturb and observe (P&O) based MPPT method ...
RAMASAMY, S.   +2 more
doaj   +1 more source

A class of analog CMOS circuits based on the square-law characteristic of an MOS transistor in saturation [PDF]

open access: yes, 1979
The examined class of circuits includes voltage multipliers, current multipliers, linear V-I convertors, linear I-V convertors, current squaring circuits, and current divider circuits.
Bult, Klaas, Wallinga, Hans
core   +3 more sources

The Parametric Optimization of Voltage Multiplier

open access: yesInternational Journal of Computing, 2021
The evolutionary model of voltage multiplier parametric optimization which includes 5 diodes and 5 capacitors is reviewed. It executes the transformation of alternating into constant voltage using a five times larger amplitude. The valve work is modelled according to the scheme of an ideal key.
Volodymyr Samotyy   +2 more
openaire   +2 more sources

KLK7 overexpression promotes an aggressive phenotype and facilitates peritoneal dissemination in colorectal cancer cells

open access: yesFEBS Open Bio, EarlyView.
KLK7, a tissue kallikrein‐related peptidase, is elevated in advanced colorectal cancer and associated with shorter survival. High KLK7 levels in ascites correlate with peritoneal metastasis. In mice, KLK7 overexpression increases metastasis. In vitro, KLK7 enhances cancer cell proliferation, migration, adhesion, and spheroid formation, driving ...
Yosr Z. Haffani   +6 more
wiley   +1 more source

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