Results 51 to 60 of about 33,314 (300)

High Voltage Step-Up Boost Converter Based on a Three-Winding-Coupled Inductor With Voltage Multiplier Cell

IEEE Access
The present paper endeavors to make a significant contribution to the field of high-voltage non-isolated dc-dc converters. This is achieved by utilizing a voltage multiplier cell based on the three-winding coupled inductor technique.
Carolina Albuquerque Caldeira, Mario Lucio da Silva Martins, Marcelo Cabral Cavalcanti, Antonio Dutra Dantas de Almeida, Eduardo Augusto Oliveira Barbosa, Leonardo Rodrigues Limongi   +5 more
doaj   +1 more source

Low Voltage Floating Gate MOS Transistor Based Four-Quadrant Multiplier [PDF]

, 2014
This paper presents a four-quadrant multiplier based on square-law characteristic of floating gate MOSFET (FGMOS) in saturation region. The proposed circuit uses square-difference identity and the differential voltage squarer proposed by Gupta et al.
Gupta, M., Singh, U., Srivastava, R.
core   +1 more source

Aggressive prostate cancer is associated with pericyte dysfunction

Molecular Oncology, EarlyView.
Tumor‐produced TGF‐β drives pericyte dysfunction in prostate cancer. This dysfunction is characterized by downregulation of some canonical pericyte markers (i.e., DES, CSPG4, and ACTA2) while maintaining the expression of others (i.e., PDGFRB, NOTCH3, and RGS5).
Anabel Martinez‐Romero, Ane Martinez‐Larrinaga, Joaquim Grego‐Bessa, Saioa Garcia‐Longarte, Hielke van Splunder, Ianire Astobiza, Amaia Ercilla, Laura Bozal‐Basterra, Isabel Mendizabal, Pilar Villacampa, Arkaitz Carracedo, Mariona Graupera   +11 more
wiley   +1 more source

An extendable soft‐switched high step‐up converter with near zero‐ripple input current suitable for fuel cell‐powered applications

IET Renewable Power Generation, 2022
In this paper, an extendable high step‐up topology is presented for the low input voltage applications, that is, fuel cell (FC) source. The proposed converter eliminates the pulsating input current and reduces the high input current ripple.
Morteza Dezhbord, Milad Babalou, Parham Mohseni, Md. Rabiul Islam, Lida Ebrahimi Vafaei, Seyed Hossein Hosseini   +5 more
doaj   +1 more source

Glycosylated LGALS3BP is highly secreted by bladder cancer cells and represents a novel urinary disease biomarker

Molecular Oncology, EarlyView.
Urinary LGALS3BP is elevated in bladder cancer patients compared to healthy controls as detected by the 1959 antibody–based ELISA. The antibody shows enhanced reactivity to the high‐mannose glycosylated variant secreted by cancer cells treated with kifunensine (KIF).
Asia Pece, Giulio Lovato, Ilaria Cela, Arianna Mercatelli, Benedetta Ferro, Jussi Nikkola, Sara Pagotto, Tommaso Grottola, Vincenzo De Laurenzi, Rossella Cicchetti, Antonio Marchetti, Luigi Schips, Rossano Lattanzio, Stefano Iacobelli, Emily Capone, Peter Black, Mads Daugaard, Michele Marchioni, Gianluca Sala   +18 more
wiley   +1 more source

A Single Switch High Step-Up DC-DC Converter Based on Tri-Winding Coupled Inductor for Renewable Energy Applications

International Transactions on Electrical Energy Systems, 2022
This article introduces a novel nonisolated single-switch high step-up DC-DC converter using a tri-winding coupled inductor (TWCL) for renewable energy applications such as PV systems.
Mana Hosseinzadehlish, Seyed Majid Hashemzadeh, Saeed Pourjafar, Ebrahim Babaei   +3 more
doaj   +1 more source

CDK11 inhibition induces cytoplasmic p21WAF1 splice variant by p53 stabilisation and SF3B1 inactivation

Molecular Oncology, EarlyView.
CDK11 inhibition stabilises the tumour suppressor p53 and triggers the production of an alternative p21WAF1 splice variant p21L, through the inactivation of the spliceosomal protein SF3B1. Unlike the canonical p21WAF1 protein, p21L is localised in the cytoplasm and has reduced cell cycle‐blocking activity.
Radovan Krejcir, Lukasz Arcimowicz, Lucia Martinkova, Vaclav Hrabal, Filip Zavadil Kokas, Tomas Henek, Martina Kucerikova, Ondrej Bonczek, Pavlina Zatloukalova, Lenka Hernychova, Philip J. Coates, Borivoj Vojtesek, David P. Lane   +12 more
wiley   +1 more source

A processing element architecture for high-density focal plane analog programmable array processors [PDF]

, 2002
The architecture of the elementary Processing Element - PE- used in a recently designed 128×128 Focal Plane Analog Programmable Array Processor is presented.
Domínguez Castro, Rafael, Espejo Meana, Servando Carlos, Liñán Cembrano, Gustavo, Rodríguez Vázquez, Ángel Benito   +3 more
core   +1 more source

Dual targeting of RET and SRC synergizes in RET fusion‐positive cancer cells

Molecular Oncology, EarlyView.
Despite the strong activity of selective RET tyrosine kinase inhibitors (TKIs), resistance of RET fusion‐positive (RET+) lung cancer and thyroid cancer frequently occurs and is mainly driven by RET‐independent bypass mechanisms. Son et al. show that SRC TKIs significantly inhibit PAK and AKT survival signaling and enhance the efficacy of RET TKIs in ...
Juhyeon Son, Lily L. Remsing Rix, Bin Fang, Eric A. Welsh, Nicole V. Bremer, Valentina Foglizzo, Paola Roa, Nickole Sigcha‐Coello, Yi Liao, Eric B. Haura, Alexander Drilon, John M. Koomen, Emiliano Cocco, Uwe Rix   +13 more
wiley   +1 more source

Transcriptional network analysis of PTEN‐protein‐deficient prostate tumors reveals robust stromal reprogramming and signs of senescent paracrine communication

Molecular Oncology, EarlyView.
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice, Jose I. Lopez, Aitziber Ugalde‐Olano, Maite Zufiaurre, Ianire Astobiza, Natalia Martin‐Martin, Laura Bozal‐Basterra, Saioa Garcia‐Longarte, Amaia Zabala‐Letona, Sofia Rey, Aida Santos‐Martin, Miguel Unda, Ana Loizaga‐Iriarte, Mariona Graupera, Paolo Nuciforo, Arkaitz Carracedo, Isabel Mendizabal   +16 more
wiley   +1 more source