Results 71 to 80 of about 27,555 (281)
Design issues of arithmetic structures in adiabatic logic [PDF]
Advances in Radio Science, 2007 Since adiabatic logic uses a supply that incorporates both supply voltage and clock signal in one line, adiabatic logic systems have a built-in micro-pipelined architecture. Considering this fact, different design constraints have to be observed compared
Ph. Teichmann +3 more
doaj
ACE16K: A 128×128 focal plane analog processor with digital I/O [PDF]
, 2002 This paper presents a new generation 128×128 focal-plane analog programmable array processor (FPAPAP), from a system level perspective, which has been manufactured in a 0.35 μm standard digital 1P-5M CMOS technology. The chip has been designed to achieve
Domínguez Castro, Rafael +3 more
core +1 more source
Molecular Oncology, EarlyView.CDK11 inhibition stabilises the tumour suppressor p53 and triggers the production of an alternative p21WAF1 splice variant p21L, through the inactivation of the spliceosomal protein SF3B1. Unlike the canonical p21WAF1 protein, p21L is localised in the cytoplasm and has reduced cell cycle‐blocking activity.
Radovan Krejcir +12 more
wiley +1 more source
AC OPF in Radial Distribution Networks - Parts I,II [PDF]
, 2015 The optimal power-flow problem (OPF) has played a key role in the planning and operation of power systems. Due to the non-linear nature of the AC power-flow equations, the OPF problem is known to be non-convex, therefore hard to solve.
Boudec, Jean-Yves Le +3 more
core +1 more source
Micromegas operation in high pressure xenon: charge and scintillation readout
, 2010 The operational characteristics of a Micromegas operating in pure xenon at the pressure range of 1 to 10 bar are investigated. The maximum charge gain achieved in each pressure is approximately constant, around 4x10^2, for xenon pressures up to 5 bar and
+18 more
core +1 more source
Dual targeting of RET and SRC synergizes in RET fusion‐positive cancer cells
Molecular Oncology, EarlyView.Despite the strong activity of selective RET tyrosine kinase inhibitors (TKIs), resistance of RET fusion‐positive (RET+) lung cancer and thyroid cancer frequently occurs and is mainly driven by RET‐independent bypass mechanisms. Son et al. show that SRC TKIs significantly inhibit PAK and AKT survival signaling and enhance the efficacy of RET TKIs in ...
Juhyeon Son +13 more
wiley +1 more source
Low Voltage High Performance CMOS Current Mode Four-Quadrant Analog Multiplier Circuit [PDF]
Radioengineering, 2022 This paper describes a new CMOS current mode four-quadrant analog multiplier circuit. The proposed design is based on a high performance squarer cell, whose main core is realized by the up–down topology trans-linear loop using flipped voltage followers ...
T. Ettaghzouti +3 more
doaj
Comparing policy gradient and value function based reinforcement learning methods in simulated electrical power trade [PDF]
, 2012 In electrical power engineering, reinforcement learning algorithms can be used to model the strategies of electricity market participants. However, traditional value function based reinforcement learning algorithms suffer from convergence issues when ...
Burt, Graeme +3 more
core +1 more source
Molecular Oncology, EarlyView.Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice +16 more
wiley +1 more source
Molecular Oncology, EarlyView.Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova +25 more
wiley +1 more source