Results 121 to 130 of about 219,919 (260)

Autophagy and mitophagy in pancreatic β‐cell homeostasis and their involvement in diabetes pathophysiology

FEBS Letters, EarlyView.
This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee, Mingming Tong, Anna L. Gloyn   +2 more
wiley   +1 more source

A Novel Gudermannian Function-Driven Controller Architecture Optimized by Starfish Optimizer for Superior Transient Performance of Automatic Voltage Regulation. [PDF]

Biomimetics (Basel)
Izci D, Ekinci S, Jabari M, Kocaman B, Güneş BB, Adas E, Ahmad MA.   +6 more
europepmc   +1 more source

Golgi enzymes are retrieved from the plasma membrane to the trans‐Golgi network

FEBS Letters, EarlyView.
Golgi enzymes are traditionally considered resident proteins retained within the Golgi apparatus. Here, we demonstrate that a subset transiently reaches the cell surface and is subsequently retrieved to the trans‐Golgi network via retrograde transport. Using a nanobody‐based toolkit, we uncover a dynamic trafficking cycle of several Golgi enzymes.
Dominik P. Buser, Tina Junne
wiley   +1 more source

Disturbance observer based multiloop proportional feedback system for output voltage regulation in three phase AC to DC converters. [PDF]

Sci Rep
Lee H, Kim D, Park HC, Kim SK, Kim Y.
europepmc   +1 more source

Insights into the Voltage Regulation Mechanism of the Pore-Forming Toxin Lysenin. [PDF]

Toxins (Basel), 2018
Bryant SL, Clark T, Thomas CA, Ware KS, Bogard A, Calzacorta C, Prather D, Fologea D.   +7 more
europepmc   +1 more source

Synergistic perspectives—How single‐molecule biophysics complement biochemical understanding

FEBS Letters, EarlyView.
In this review, we discuss how ensemble biochemistry and single‐molecule approaches are complementary, outline commonly used single‐molecule techniques, and illustrate their relevance through two representative case studies: chromatin organization by SMC complexes and pathway choice during DNA double‐strand break repair.
Sara De Bragança, Eline L. Jansen, Jorine M. Eeftens   +2 more
wiley   +1 more source

ZnO nanoparticles modulate the ionic transport and voltage regulation of lysenin nanochannels. [PDF]

J Nanobiotechnology, 2017
Bryant SL, Eixenberger JE, Rossland S, Apsley H, Hoffmann C, Shrestha N, McHugh M, Punnoose A, Fologea D.   +8 more
europepmc   +1 more source

The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers

Molecular Oncology, EarlyView.
The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce, Simone Bini, Marialuisa Sponziello, Giorgio Grani, Giulia Fiscon, Paola Paci, Lorenzo Farina, Rosa Falcone, Valentina Maggisano, Sebastiano Filetti, Cosimo Durante, Antonella Verrienti   +11 more
wiley   +1 more source

Enhanced power sharing and voltage regulation for islanded nano-satellite DC microgrids in spinning flight scenarios. [PDF]

Sci Rep
Louassaa K, Guerrero JM, Khan B, Yousaf MZ, Zdiri MA, Zhang L, Sivanraju R.   +6 more
europepmc   +1 more source

Voltage regulation of connexin channel conductance. [PDF]

Yonsei Med J, 2015
Oh S, Bargiello TA.
europepmc   +1 more source