Results 161 to 170 of about 3,069,371 (299)

KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer

open access: yesMolecular Oncology, EarlyView.
Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan   +16 more
wiley   +1 more source

Insights into the Voltage Regulation Mechanism of the Pore-Forming Toxin Lysenin. [PDF]

open access: yesToxins (Basel), 2018
Bryant SL   +7 more
europepmc   +1 more source

Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer

open access: yesMolecular Oncology, EarlyView.
Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley   +1 more source

ZnO nanoparticles modulate the ionic transport and voltage regulation of lysenin nanochannels. [PDF]

open access: yesJ Nanobiotechnology, 2017
Bryant SL   +8 more
europepmc   +1 more source

Transcriptional profiling of circulating extracellular vesicles from prebiopsy prostate cancer patients

open access: yesMolecular Oncology, EarlyView.
RNA profiling of circulating extracellular vesicles (EVs) from blood samples of men undergoing prostate biopsy identifies transcripts associated with clinically significant prostate cancer. Integrative analysis with public tumor datasets links EV‐derived gene signatures to tumor stage and progression‐free survival, highlighting CASP3, XRCC2, and RIT1 ...
Stefan Werner   +14 more
wiley   +1 more source

An investigation of delay fault testing for multi voltage design

open access: yes, 2009
Multi Voltage Design (MVD) has been successfully applied in contemporary processors as a technique to reduce energy consumption. This work is aimed at finding a generalised delay testing method for MVD.
Zain Ali, Noohul Basheer
core  

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