Results 131 to 140 of about 221,172 (361)

Inhibiting stearoyl‐CoA desaturase suppresses bone metastatic prostate cancer by modulating cellular stress, mTOR signaling, and DNA damage response

open access: yesFEBS Letters, EarlyView.
Bone metastasis in prostate cancer (PCa) patients is a clinical hurdle due to the poor understanding of the supportive bone microenvironment. Here, we identify stearoyl‐CoA desaturase (SCD) as a tumor‐promoting enzyme and potential therapeutic target in bone metastatic PCa.
Alexis Wilson   +7 more
wiley   +1 more source

СКЛАДОВІ ПОТУЖНОСТІ ТИРИСТОРНОГО РЕГУЛЯТОРА НАПРУГИ З АКТИВНИМ НАВАНТАЖЕННЯМ

open access: yesПраці Інституту електродинаміки Національної академії наук України
A study of the power balance of the semiconductor voltage regulator on an active load with phase control by two-operation thyristors was carried out. The suitability of its use for simultaneous obtaining of the reactive power resource for distribution ...
Є.І. Федів   +1 more
doaj   +1 more source

Method and apparatus for battery charge control Patent [PDF]

open access: yes, 1969
Battery charging system with cell to cell voltage ...
Hennigan, T. J.   +2 more
core   +1 more source

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

open access: yesFEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee   +3 more
wiley   +1 more source

Battery Energy Storage System (BESS) as a voltage control at substation based on the defense scheme mechanism

open access: yesJurnal Ilmiah SINERGI
Battery Energy Storage Systems (BESS) can improve power quality in a grid with various integrated energy resources. The BESS can adjust the supply and demand to maintain a more stable, reliable, and resilient power system. Connected to the grid, BESS can
Zainal Arifin   +3 more
doaj   +1 more source

A dc servosystem including an ac motor [PDF]

open access: yes, 1971
Closed loop servosystem for variable speed tape recorders on board ...
Bahm, E. J.
core   +1 more source

β‐TrCP overexpression enhances cisplatin sensitivity by depleting BRCA1

open access: yesMolecular Oncology, EarlyView.
Low levels of β‐TrCP (Panel A) allow the accumulation of BRCA1 and CtIP, which facilitate the repair of cisplatin‐induced DNA damage via homologous recombination (HR) and promote tumor cell survival. In contrast, high β‐TrCP expression (Panel B) leads to BRCA1 and CtIP degradation, impairing HR repair, resulting in persistent DNA damage and apoptosis ...
Rocío Jiménez‐Guerrero   +8 more
wiley   +1 more source

Temperature compensated digital inertial sensor [PDF]

open access: yes, 1974
A circuit which maintains the inertial element of a gyroscope or accelerometer at a constant position by delivering pulses to a rebalancing motor is discussed.
Hand, P. J.
core   +1 more source

Nicotinamide N‐methyltransferase promotes drug resistance in lung cancer, as revealed by nascent proteomic profiling

open access: yesMolecular Oncology, EarlyView.
AZD9291 has shown promise in targeted cancer therapy but is limited by resistance. In this study, we employed metabolic labeling and LC–MS/MS to profile time‐resolved nascent protein perturbations, allowing dynamic tracking of drug‐responsive proteins. We demonstrated that increased NNMT expression is associated with drug resistance, highlighting NNMT ...
Zhanwu Hou   +5 more
wiley   +1 more source

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