Results 71 to 80 of about 1,080,885 (257)
FEBS Letters, EarlyView.Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley +1 more source
Multilevel multistate hybrid voltage regulator [PDF]
, 2015 In this work, a new set of voltage regulators as well as some controlling methods and schemes are proposed. While normal switched capacitor voltage regulators are easy integrable, they are suffering from charge sharing losses as well as fast degradation ...
Abdulslam, Abdullah Amgad Abdulaziz
core
From mice to humans—divergent strategies for intestinal homeostasis and regeneration
FEBS Letters, EarlyView.Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa +2 more
wiley +1 more source
Modelling stem cell differentiation related processes—A practical overview for biologists
FEBS Letters, EarlyView.Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar +4 more
wiley +1 more source
Design and analysis strategies for robust microbiome ageing research
FEBS Letters, EarlyView.The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik +5 more
wiley +1 more source
Estudo de um condicionador de tensão alternada com compensação série, utilizando um conversor indireto CA-CA com alimentação a jusante [PDF]
, 2007 Dissertação (mestrado) - Universidade Federal de Santa Catarina, Centro Tecnológico. Programa de Pós-Graduação em Engenharia ElétricaEste trabalho apresenta o estudo de um condicionador de tensão ca operando em malha fechada.
Soeiro, Thiago Batista
core
MANAS: Journal of EngineeringThis paper focuses on utility voltage regulator using ac – dc – ac converter topology for single-phase resistive load applications. The power circuit converter has been presented, to solve the problem of undesired voltage supply to domestic and ...
Gerald Diyoke
doaj +1 more source
High-efficiency buck–boost converter and its control strategy suitable for wide voltage range
The Journal of Engineering, 2019 In view of the need of near-space vehicle energy management system to adapt to wide input and wide output voltage range, this study presents a high-efficiency buck–boost converter and its control strategy suitable for wide voltage range. In this study, a
Dong Baolei +4 more
doaj +1 more source
FEBS Letters, EarlyView.CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens +8 more
wiley +1 more source
Reconstructing enzyme evolution by protein engineering
FEBS Letters, EarlyView.Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler +2 more
wiley +1 more source