Results 91 to 100 of about 1,041,670 (295)

Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential

FEBS Letters, EarlyView.
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta, Hari Baskar Balasubramanian, Amir Pasokh, Marietta Zille   +3 more
wiley   +1 more source

Low-speed Sensorless Control Technology of PMSM Based on Dual PWM Regulators

Gong-kuang zidonghua, 2011
In order to improve the poor performance of sensorless control of PMSM using extended Kalman filter at low speed,the paper proposed a novel low-speed sensorless control technology of PMSM based on dual PWM regulators.
REN Ju-yong, GU Shan-mao
doaj  

Structure‐forward targeting of claudins with synthetic binders

FEBS Letters, EarlyView.
Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley   +1 more source

Nutrient/TOR signaling controls adipose mitochondrial transcription factor A (TFAM) to regulate organismal growth in Drosophila

FEBS Letters, EarlyView.
Animals must match their growth rate to available nutrients. We show that in Drosophila larvae, the nutrient‐sensing TOR kinase controls growth by regulating levels of TFAM, a key regulator of mitochondrial function, in the adipose tissue. When nutrients are abundant, high TOR activity suppresses TFAM, lowering mitochondrial bioenergetic activity and ...
Shrivani Sriskanthadevan‐Pirahas, Shahoon Khan, Abhishek Sharma, Byoungchun Lee, Savraj S. Grewal   +4 more
wiley   +1 more source

Evaluation of Voltage Regulators for Dual-Loop Control of Voltage-Controlled VSCs

, 2019
This paper presents an evaluation for the voltage regulators adopted in the digital dual-loop voltage-controlled, LC-filtered voltage-source converters.
Yicheng Liao, Wang, Xiongfei; id_orcid, Liao, Yicheng, Xiongfei Wang   +3 more
core   +1 more source

Voltage security evaluation based on perturbation method [PDF]

, 2009
This is the post-print version of the final paper published in International Journal of Electrical Power & Energy Systems. The published article is available from the link below. Changes resulting from the publishing process, such as peer review, editing,
Mousavi, A, Rashidinejad, M
core   +1 more source

Linear Voltage Regulators With Gate-Driving Buffer for Automotive Applications

IEEE Access
This work presents a novel linear voltage regulator that fulfills two key requirements for automotive applications: it operates over a wide input voltage range and passes a very challenging test, compulsory for vehicles of up to 3.5t.
Alina-Teodora Grajdeanu, Cristian Raducan, Marius Neag, Ionut-Alin Ilie   +3 more
doaj   +1 more source

Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics

FEBS Letters, EarlyView.
Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt, Ana‐Maria Sandru, Georg Vucak, Sebastian Didusch, Biljana Riemelmoser, Karin Ehrenreiter, Markus Hartl, Lukas A. Huber, Manuela Baccarini   +8 more
wiley   +1 more source

Machine Learning-Based Package-Embedded Inductor Optimization for Integrated Voltage Regulators

IEEE Open Journal of Power Electronics
This study presents an algorithm based on an artificial neural network (ANN) to optimize the design of inductors used in fully integrated voltage regulators (FIVRs).
GiWon Kim, HyunJoon Jeong, Jisoo Hwang, SoYoung Kim   +3 more
doaj   +1 more source

Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation

FEBS Letters, EarlyView.
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang, Ruslana Romaniuk, Hristo L. Svilenov   +2 more
wiley   +1 more source