Epilepsy‐Associated Variants of a Single SCN1A Codon Exhibit Divergent Functional Properties
ABSTRACT Objective Pathogenic variants in SCN1A, which encodes the voltage‐gated sodium channel NaV1.1, are associated with multiple epilepsy syndromes exhibiting a range of clinical severity. SCN1A variants are reported in different syndromes, including Dravet syndrome, which is associated with loss‐of‐function, whereas neonatal/infantile‐onset ...
Lanie N. Liebovitz +3 more
wiley +1 more source
Performance of a 14.9-kW laminated-frame dc series motor with chopper controller [PDF]
Traction motor using two types of excitation: ripple free dc from a motor generator set for baseline data and chopped dc as supplied by a battery and chopper controller was tested.
Schwab, J. R.
core +1 more source
A holistic DC link architecture design method for multiphase Integrated Modular Motor Drives [PDF]
This article describes a holistic DC link architecture design method that considers the end-application of the drive and its corresponding constraints e.g. the maximum battery ripple current for a battery-supplied inverter.
De Belie, Frederik +4 more
core +2 more sources
Multidimensional Profiling of MRI‐Negative Temporal Lobe Epilepsy Uncovers Distinct Phenotypes
ABSTRACT Objective Although hippocampal sclerosis (TLE‐HS) represents the most frequent cause of temporal lobe epilepsy (TLE), up to 30% of patients show no lesion on visual MRI inspection (TLE‐MRIneg). These cases pose diagnostic and therapeutic challenges and are underrepresented in surgical series.
Alice Ballerini +28 more
wiley +1 more source
Reducing the converter loss, sub-module voltage ripple and handling DC short-circuit faults in high-voltage direct current systems are crucial for the economical and reliable operation of modular multilevel converters (MMCs).
Muchao Xiang +3 more
doaj +1 more source
The measurement of very low conductivity and dielectric loss in XLPE cables: A possible method to detect degradation due to thermal aging [PDF]
The dielectric response of crosslinked polyethylene (XLPE) insulated, miniature power cables, extruded with inner and outer semicons, was measured over the frequency range 10-4 to 104 Hz at temperatures from 20 to 100 °C.
Dissado, L. A. +4 more
core +1 more source
Epigenetic reprogramming in hematopoietic stem and progenitor cells (HSPCs) and downstream myeloid cells, mediated by H3.3 downregulation and endogenous retroelement (ERE) overexpression, contributes to the progression of multiple sclerosis (MS). ABSTRACT Background Skewed myelopoiesis in the bone marrow has been identified as a key driver of multiple ...
Li‐Mei Xiao +6 more
wiley +1 more source
With the increasing penetration of DC systems into the high voltage and medium voltage power industry, DC voltage is becoming common for distribution/transmission and to supply different typologies of loads. The allowable extent of AC ripple superimposed
Giovanni Gardan, Gian Carlo Montanari
doaj +1 more source
A Voltage Calibration Chain for Meters Used in Measurements of EV Inductive Power Charging
The inductive charging of electric vehicles requires specific measurement and calibration systems. In fact, the measurement of power on board involves DC signals, which are superimposed to a significant AC ripple up to or over 150 kHz, depending on the ...
Crotti, G. +5 more
core +1 more source
Improved current-regulated delta modulator for reducing switching frequency and low-frequency current error in permanent magnet brushless AC drives [PDF]
The conventional current-regulated delta modulator (CRDM) results in a high current ripple and a high switching frequency at low rotational speeds, and in low-frequency current harmonics, including a fundamental current error, at high rotational speeds ...
Howe, D., Wipasuramonton, P., Zhu, Z.Q.
core +1 more source

