Results 201 to 210 of about 758,847 (249)

Inhibition of late sodium current prevents pathological hyperactivation of calcium/calmodulin‐dependent protein kinase IIδ in a murine model of acute doxorubicin‐related cardiotoxicity

British Journal of Pharmacology, EarlyView.
Abstract Background and Purpose Doxorubicin (DOX) is a highly effective anthracycline, whose clinical application for cancer is limited by cardiotoxicity. The mechanisms underlying doxorubicin‐induced toxic cardiomyopathy (DICM) involve electrophysiological remodelling with intracellular Na+ overload because of increased late INa and hyperactivation of
Anna‐Lena Feder, Anna‐Maria Pfützenreuter, Lea Maria Funke, Maria Johanna Baier, Daniel Tarnowski, Laura Stengel, Lars Siegfried Maier, Can Martin Sag   +7 more
wiley   +1 more source

Modulatory Effects of Bioactive Phytoconstituents on the Amplitude and Gating Properties of Membrane Ion Channels. [PDF]

Molecules
Wu SN, Froldi G, Wang YJ, Liutkevičienė R.   +3 more
europepmc   +1 more source

Metabolic remodelling in anthracycline cardiotoxicity: mechanisms and therapeutic insights

British Journal of Pharmacology, EarlyView.
Cardiac metabolic remodelling in anthracycline‐induced cardiomyopathy and metabolically oriented cardioprotective strategies. Schematic representation of substrate utilization, mitochondrial bioenergetic function and metabolic flexibility in the healthy heart, in anthracycline‐induced cardiomyopathy and under potential cardioprotective interventions ...
Giulia Guerra, Francesco Niro, Marco Mergiotti, Giovanni Gavatorta, Emilio Hirsch, Alessandra Ghigo   +5 more
wiley   +1 more source

A hybrid AI framework for identification of power quality disturbances in electrical network. [PDF]

Sci Rep
Debnath R, Majumder A, Jain AK, Dey B.
europepmc   +1 more source

Behaviour Support in Dentistry Core Outcomes (BeSiDe‐CO): A Core Outcome Set Development Study

Community Dentistry and Oral Epidemiology, EarlyView.
ABSTRACT Objectives To develop a Core Outcome Set suitable for adults and children for use in studies of Dental Behaviour Support (DBS) techniques, including non‐pharmacological DBS, sedation and General Anaesthesia research. Methods Two systematic reviews generated a preliminary list of candidate outcomes that were shared with Key Stakeholders (KSG ...
Caoimhin Mac Giolla Phadraig, Isabel C. Olegário, Shaelynn Hsu, Maryam Al Zayer, Aisyah Binti Ahmad Fisal, Alison Dougall, Gareth B. Kitchen, Henry F. Duncan, Sarah Baker, Sharat Pani, Sreekanth Kumar Mallineni, Mandy Daly, The BeSiDe COS Collaboration, Tracey Scott, Carolyn Akintola, Éilish Burke, Steve Moore, Barbara Vallo, Jacobo Posse Limerese, Karin Alexandra Van Nes, Maiken Bagger, Olive Healy, Andrew Geddis‐Regan   +22 more
wiley   +1 more source

Control strategy for offshore wind power HVDC transmission system based on series-connected DRU-MMC topology. [PDF]

Sci Rep
Gan H, Xiao H.
europepmc   +1 more source

FlowGS: Controlling Information Flow for Graph‐Based Interaction in 3D Gaussian Splatting

Computer Graphics Forum, EarlyView.
Abstract 3D Gaussian Splatting (3DGS) has recently enabled real‐time, high‐quality novel view synthesis. However, its formulation treats each Gaussian independently, lacking explicit information exchange between neighboring elements and limiting its ability to capture local structure.
T. Jia, R. Sun, W. Shi
wiley   +1 more source

Hybrid Forecast-Enabled Adaptive Crowbar Coordination for LVRT Enhancement in DFIG Wind Turbines. [PDF]

Entropy (Basel)
Su X, Kim H, Kim C, Zhang M, Jung H.
europepmc   +1 more source

Extreme weather and economic crisis in the 1430s in England, and the implications for tenurial change

The Economic History Review, EarlyView.
Abstract The 1430s were characterized by extreme weather conditions, food and fodder shortages, and high mortalities among animals and humans, although the severity of events and their consequences in England have received limited attention. The economic downturn and the depressed customary land market in this decade marked the beginning of the Great ...
Mark Bailey
wiley   +1 more source