Results 101 to 110 of about 111,252 (300)

Soma-Axon Coupling Configurations That Enhance Neuronal Coincidence Detection [PDF]

, 2019
Coincidence detector neurons transmit timing information by responding preferentially to concurrent synaptic inputs. Principal cells of the medial superior olive (MSO) in the mammalian auditory brainstem are superb coincidence detectors.
Goldwyn, Joshua H., Remme, M. W. H., Rinzel, J.   +2 more
core   +1 more source

Lipid Nanoparticles for the Delivery of CRISPR/Cas9 Machinery to Enable Site‐Specific Integration of CFTR and Mutation‐Agnostic Disease Rescue

Advanced Functional Materials, EarlyView.
Lipid nanoparticles (LNPs) are optimized to co‐deliver Cas9‐encoding messenger RNA (mRNA), a single guide RNA (sgRNA) targeting the endogenous cystic fibrosis transmembrane conductance regulator (CFTR) gene, and homologous linear double‐stranded donor DNA (ldsDNA) templates encoding CFTR.
Ruth A. Foley, Paul G. Ayoub, Vrishti Sinha, Colin Juett, Alicia Sanoyca, Emily C. Duggan, Lindsay E. Lathrop, Priyanka Bhatt, Kevin Coote, Beate Illek, Brigitte N. Gomperts, Donald B. Kohn, Steven J. Jonas   +12 more
wiley   +1 more source

Wild oscillations in a nonlinear neuron model with resets: (II) Mixed-mode oscillations

, 2017
This work continues the analysis of complex dynamics in a class of bidimensional nonlinear hybrid dynamical systems with resets modeling neuronal voltage dynamics with adaptation and spike emission.
Rubin, Jonathan E., Signerska-Rynkowska, Justyna, Touboul, Jonathan, Vidal, Alexandre   +3 more
core   +2 more sources

Phase-responsiveness transmission in a network of quadratic integrate-and-fire neurons [PDF]

, 2020
In the study of the dynamics of neuronal networks, it is interesting to see how the interaction between neurons can elicit different behaviours in each individual one.
Arqué Pérez, Ferran
core  

Combinatorial Synthesis of Next Generation Water‐Soluble Quaternized N‐Halamine Oligomers with Long‐Lasting Antiviral Properties

Advanced Functional Materials, EarlyView.
A combinatorial library of dual‐functional antiviral oligomers incorporating N‐halamine and quaternary ammonium functionalities is developed for long‐lasting antiviral activity. The lead materials exhibit rapid and durable antiviral activity against SARS‐CoV‐2 variants and influenza H1N1, with 4 to 5 log reduction in viral copies at 5 mg mL−1 ...
Eid Nassar‐Marjiya, Konda Reddy Kunduru, Krishanu Ghosal, Luna Rizik, Nofar Atari, Mahran Daifa, Neta Kutner, Bassma Khamaisi, Qi Wu, Simran Jindal, Merna Shaheen‐Mualim, Ranabir Majumder, Mahitosh Mandal, Michal Mandelboim, Shady Farah   +14 more
wiley   +1 more source

Inactivating SARS‐CoV‐2 Virus with MOF‐Composites as Smart Face Masks

Advanced Functional Materials, EarlyView.
In situ preparation and functionalization of MOF@Cotton fabrics as smart face masks for the immobilization of proteins and inactivation viruses, such as SARS‐CoV‐2. Abstract The significant impact of the SARS‐CoV‐2 (COVID‐19) pandemic outbreak on people's lives has highlighted the urgent need for effective personal protective equipment.
Romy Ettlinger, Aamod V. Desai, Hau Lam Jody Cheong, Louise L. Major, Terry K. Smith, Aaron B. Naden, Jane Hilton, Catherine S. Adamson, A. Robert Armstrong, Russell E. Morris   +9 more
wiley   +1 more source

Reduced Common Mode Voltage PWM Strategy With Optimized Switching Sequence for Three Phase Motor Drives

IEEE Access
This paper proposes a pulse width modulation (PWM) switching sequence strategy aimed at minimizing common-mode voltage (CMV) in three-phase motor drive systems.
Suji Seo, Sehwan Kim, Hyeon-Jae Shin, Cheewoo Lee, Jae Suk Lee   +4 more
doaj   +1 more source

Programmable DNA‐Peptide Hybrid Nanostructures for Potent Neutralization of Multiple Influenza a Virus Subtypes

Advanced Functional Materials, EarlyView.
A multivalent antiviral platform based on honeycomb‐shaped DNA nanostructures (HC–Urumin) is developed to enhance the potency and breadth of the host defense peptide Urumin. Through spatially patterned trimeric presentation, HC–Urumin disrupts influenza A virus entry, improves cell viability, and reduces disease severity in vivo‐offering a modular and ...
Saurabh Umrao, Abhisek Dwivedy, Payton L. Haak, Dhanush Gandavadi, Laurie A. Rund, Chi Chen, Vineetha Mareddy, Lifeng Zhou, Jinwei Duan, Ying Fang, Andrew J. Steelman, Xing Wang   +11 more
wiley   +1 more source

KInNeSS: A Modular Framework for Computational Neuroscience [PDF]

, 2007
Making use of very detailed neurophysiological, anatomical, and behavioral data to build biological-realistic computational models of animal behavior is often a difficult task.
Ames, Heather, Fontenberry, Bret, Gorchetchnikov, Anatoli, Léveillé, Jasmin, Versace, Massimiliano   +4 more
core   +2 more sources

Delay Learning Architectures for Memory and Classification

, 2014
We present a neuromorphic spiking neural network, the DELTRON, that can remember and store patterns by changing the delays of every connection as opposed to modifying the weights.
Basu, Arindam, Hamilton, Tara Julia, Hussain, Shaista, Wang, R.   +3 more
core   +1 more source