Results 61 to 70 of about 111,252 (300)

Sharpness of spike initiation in neurons explained by compartmentalization. [PDF]

open access: yesPLoS Computational Biology, 2013
In cortical neurons, spikes are initiated in the axon initial segment. Seen at the soma, they appear surprisingly sharp. A standard explanation is that the current coming from the axon becomes sharp as the spike is actively backpropagated to the soma ...
Romain Brette
doaj   +1 more source

Subtype‐specific enhancer RNAs define transcriptional regulators and prognosis in breast cancers

open access: yesMolecular Oncology, EarlyView.
This study employed machine learning methodologies to perform the subtype‐specific classification of RNA‐seq data sets, which are mapped on enhancers from TCGA‐derived breast cancer patients. Their integration with gene expression (referred to as ProxCReAM eRNAs) and chromatin accessibility profiles has the potential to identify lineage‐specific and ...
Aamena Y. Patel   +6 more
wiley   +1 more source

New Nine-Level Common-Ground Multilevel Inverter With Boosting Capability for Renewable Energies

open access: yesIEEE Open Journal of the Industrial Electronics Society
In recent years, several common-ground switched-capacitor transformerless (CGSC-TL) dc–ac multilevel power converters have been introduced, providing advantages such as multilevel output voltage, voltage boosting, and mitigated leakage current ...
Maysam Abbasi   +8 more
doaj   +1 more source

A CMOS implementation of a spike event coding scheme for analog arrays [PDF]

open access: yes, 2009
This paper presents a CMOS circuit implementation of a spike event coding/decoding scheme for transmission of analog signals in a programmable analog array. This scheme uses spikes for a time representation of analog signals.
Gouveia, L.C.   +2 more
core   +1 more source

RIPK4 function interferes with melanoma cell adhesion and metastasis

open access: yesMolecular Oncology, EarlyView.
RIPK4 promotes melanoma growth and spread. RIPK4 levels increase as skin lesions progress to melanoma. CRISPR/Cas9‐mediated deletion of RIPK4 causes melanoma cells to form less compact spheroids, reduces their migratory and invasive abilities and limits tumour growth and dissemination in mouse models.
Norbert Wronski   +9 more
wiley   +1 more source

Design and evaluation of SiC multichip power module with low and symmetrical inductance

open access: yesThe Journal of Engineering, 2019
Compared to silicon devices, silicon carbide (SiC) devices have much lower C(oss) and Q(g); they can switch at much higher speed, SiC power modules are thus more sensitive to stray parameters.
Shao Weihua   +4 more
doaj   +1 more source

Dendritic integration in olfactory bulb granule cells upon simultaneous multispine activation: Low thresholds for nonlocal spiking activity.

open access: yesPLoS Biology, 2020
The inhibitory axonless olfactory bulb granule cells form reciprocal dendrodendritic synapses with mitral and tufted cells via large spines, mediating recurrent and lateral inhibition.
Max Mueller, Veronica Egger
doaj   +1 more source

The space-clamped Hodgkin-Huxley system with random synaptic input: inhibition of spiking by weak noise and analysis with moment equations

open access: yes, 2016
We consider a classical space-clamped Hodgkin-Huxley model neuron stimulated by synaptic excitation and inhibition with conductances represented by Ornstein-Uhlenbeck processes.
Ditlevsen, Susanne, Tuckwell, Henry C.
core   +1 more source

Tumor‐stromal crosstalk and macrophage enrichment are associated with chemotherapy response in bladder cancer

open access: yesFEBS Open Bio, EarlyView.
Chemoresistance in bladder cancer: Macrophage recruitment associated with CXCL1, CXCL5 and CXCL8 expression is characteristic of Gemcitabine/Cisplatin (Gem/Cis) Non‐Responder tumors (right side) while Responder tumors did not show substantial tumor‐stromal crosstalk (left side). All biological icons are attributed to Bioicons: carcinoma, cancerous‐cell‐
Sophie Leypold   +11 more
wiley   +1 more source

Investigation of non linear dynamics of an excitable magnetron sputtering plasma

open access: yesResults in Physics, 2019
In this paper nonlinear dynamical behaviour of an excitable DC magnetron sputtering plasma has been investigated. Initially, plasma exhibited fixed point dynamics whereas with the increase in the discharge voltage, spikes were observed in the floating ...
Gopikishan Sabavath   +4 more
doaj   +1 more source

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