Results 61 to 70 of about 112,357 (298)

Sharpness of spike initiation in neurons explained by compartmentalization. [PDF]

open access: yesPLoS Computational Biology, 2013
In cortical neurons, spikes are initiated in the axon initial segment. Seen at the soma, they appear surprisingly sharp. A standard explanation is that the current coming from the axon becomes sharp as the spike is actively backpropagated to the soma ...
Romain Brette
doaj   +1 more source

The space-clamped Hodgkin-Huxley system with random synaptic input: inhibition of spiking by weak noise and analysis with moment equations

open access: yes, 2016
We consider a classical space-clamped Hodgkin-Huxley model neuron stimulated by synaptic excitation and inhibition with conductances represented by Ornstein-Uhlenbeck processes.
Ditlevsen, Susanne, Tuckwell, Henry C.
core   +1 more source

Visual Recovery Reflects Cortical MeCP2 Sensitivity in Rett Syndrome

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Rett syndrome (RTT) is a devastating neurodevelopmental disorder with developmental regression affecting motor, sensory, and cognitive functions. Sensory disruptions contribute to the complex behavioral and cognitive difficulties and represent an important target for therapeutic interventions.
Alex Joseph Simon   +12 more
wiley   +1 more source

New Nine-Level Common-Ground Multilevel Inverter With Boosting Capability for Renewable Energies

open access: yesIEEE Open Journal of the Industrial Electronics Society
In recent years, several common-ground switched-capacitor transformerless (CGSC-TL) dc–ac multilevel power converters have been introduced, providing advantages such as multilevel output voltage, voltage boosting, and mitigated leakage current ...
Maysam Abbasi   +8 more
doaj   +1 more source

Comparison of Langevin and Markov channel noise models for neuronal signal generation

open access: yes, 2009
The stochastic opening and closing of voltage-gated ion channels produces noise in neurons. The effect of this noise on the neuronal performance has been modelled using either approximate or Langevin model, based on stochastic differential equations or ...
A. L. Hodgkin   +15 more
core   +1 more source

A Comprehensive Overview of the Clinical, Electrophysiological, and Neuroimaging Features of BPAN: Insights From a New Case Series

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Neurodegeneration with brain iron accumulation (NBIA) comprises a genetically and clinically heterogeneous group of rare neurological disorders characterized particularly by iron accumulation in the basal ganglia. To date, 15 genes have been associated with NBIA.
Seda Susgun   +95 more
wiley   +1 more source

Design and evaluation of SiC multichip power module with low and symmetrical inductance

open access: yesThe Journal of Engineering, 2019
Compared to silicon devices, silicon carbide (SiC) devices have much lower C(oss) and Q(g); they can switch at much higher speed, SiC power modules are thus more sensitive to stray parameters.
Shao Weihua   +4 more
doaj   +1 more source

Dendritic integration in olfactory bulb granule cells upon simultaneous multispine activation: Low thresholds for nonlocal spiking activity.

open access: yesPLoS Biology, 2020
The inhibitory axonless olfactory bulb granule cells form reciprocal dendrodendritic synapses with mitral and tufted cells via large spines, mediating recurrent and lateral inhibition.
Max Mueller, Veronica Egger
doaj   +1 more source

Design and Implementation of BCM Rule Based on Spike-Timing Dependent Plasticity

open access: yes, 2012
The Bienenstock-Cooper-Munro (BCM) and Spike Timing-Dependent Plasticity (STDP) rules are two experimentally verified form of synaptic plasticity where the alteration of synaptic weight depends upon the rate and the timing of pre- and post-synaptic ...
Abbott, Derek   +3 more
core   +1 more source

Phase-responsiveness transmission in a network of quadratic integrate-and-fire neurons [PDF]

open access: yes, 2020
In the study of the dynamics of neuronal networks, it is interesting to see how the interaction between neurons can elicit different behaviours in each individual one.
Arqué Pérez, Ferran
core  

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