Results 81 to 90 of about 111,252 (300)

Methods for Suppressing Spike Voltage of ARCPI Auxiliary Switch

DEStech Transactions on Engineering and Technology Research, 2016
The Auxiliary Resonant Commutated Pole Inverter which is a kind three phase soft inverter. It is very suitable for AC driving. During the developing process, the spike voltage was produced between the auxiliary switch. Research shows that the diode in the auxiliary resonant circuit has a reverse-recovery phenomenon.
Yan Zhi-feng, Ma Xiao-jun
openaire   +2 more sources

Super‐Refractory Status Epilepticus (SRSE) in a Patient With Compound Heterozygous OPA1 Variants: Case Report and Literature Review

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Super‐Refractory Status Epilepticus (SRSE) is a rare, life‐threatening neurological emergency with unclear etiology in many cases. Mitochondrial dysfunction, often due to disease‐causing genetic variants, is increasingly recognized as a cause, with each gene producing distinct pathophysiological mechanisms.
Pouria Mohammadi, Lara Basovic, Christopher Michael McGraw   +2 more
wiley   +1 more source

Developmental and Epileptic Encephalopathy due to Biallelic Pathogenic Variants in PIGM

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective PIGM encodes a critical enzyme in the glycosylphosphatidylinositol (GPI)‐anchor biosynthesis pathway. While promoter‐region mutations in PIGM have been associated with a relatively mild phenotype characterized by portal vein thrombosis and absence seizures, recent evidence suggests that coding‐region mutations result in a more severe
Júlia Sala‐Coromina, Anna Marcé‐Grau, Barbara Masotto, Marta Codina, Lamia BenJemaa, Yasmina Elaribi, Mónica Martinez‐Gallo, Roger Colobran, Angel Sanchez‐Montañez, Irene Valenzuela, Yoshiko Murakami, Alfons Macaya   +11 more
wiley   +1 more source

Voltage Dependence of Calcium Spike Characteristics in Rat Cardiac Myocytes [PDF]

Biophysical Journal, 2012
Integral calcium release fluxes in mammalian cardiac myocytes increase in amplitude not only due to the increased recruitment of individual release sites but also due to their increased synchronization (1). Here we characterize the voltage dependence of synchronization of individual release sites at high temporal resolution.
Hotka, Matej, Janíček, Radoslav, Zahradníková, Alexandra, Poláková, Eva, Zahradníková, Alexandra, Zahradník, Ivan   +5 more
openaire   +1 more source

Epilepsy‐Associated Variants of a Single SCN1A Codon Exhibit Divergent Functional Properties

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Pathogenic variants in SCN1A, which encodes the voltage‐gated sodium channel NaV1.1, are associated with multiple epilepsy syndromes exhibiting a range of clinical severity. SCN1A variants are reported in different syndromes, including Dravet syndrome, which is associated with loss‐of‐function, whereas neonatal/infantile‐onset ...
Lanie N. Liebovitz, Christopher H. Thompson, Linda C. Laux, Alfred L. George Jr.   +3 more
wiley   +1 more source

Clinical Outcomes of SEEG‐Guided Radiofrequency Thermocoagulation in Children With Focal Drug‐Resistant Epilepsy: A Multicenter Real‐World Study

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Stereoelectroencephalography‐guided radiofrequency thermocoagulation (SEEG‐RFTC) has emerged as a safe and effective minimally invasive treatment for children with drug‐resistant focal epilepsy. Although evidence from real‐world studies remains limited, numerous pediatric cases have demonstrated promising outcomes. This retrospective
Weitao Chen, Stéphane Jean, Weihong Liu, Yihai Dai, Xinrong Fang, Xiaoqiang Wei, Shan Chen, Shiwei Song   +7 more
wiley   +1 more source

A Coupled-Inductor DC-DC Converter with Input Current Ripple Minimization for Fuel Cell Vehicles

Energies, 2019
A coupled-inductor DC-DC converter with a high voltage gain is proposed in this paper to match the voltage of a fuel cell stack to a DC link bus. The proposed converter can minimize current ripples and can also achieve a high voltage gain by adjusting ...
Fuwu Yan, Jingyuan Li, Changqing Du, Chendong Zhao, Wei Zhang, Yun Zhang   +5 more
doaj   +1 more source

Computational modeling of spike generation in serotonergic neurons of the dorsal raphe nucleu [PDF]

, 2012
We consider here a single-compartment model of these neurons which is capable of describing many of the known features of spike generation, particularly the slow rhythmic pacemaking activity often observed in these cells in a variety of species. Included
Penington, Nicholas J., Tuckwell, Henry C.   +1 more
core  

GAD65 Antibody ELISA With Extended Reportable Range: Validation and Guidance for Neurological Practice

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To (1) validate GAD65‐ELISA detection and quantification for type 1 diabetes mellitus and autoimmune neurological diagnoses, (2) correlate ELISA results (reference range < 5 IU/mL) with established radioimmunoprecipitation assay (RIA; ≤ 0.02 nmol/L), and (3) define ELISA clinical utility and pitfalls.
Andrew McKeon, Dana Olofson, Diana Anissian, Divyanshu Dubey, Eoin P. Flanagan, Max C. Herman, Sarosh R. Irani, Daniel H. Lachance, Maria A. Willrich, Sean Pittock, John R. Mills, Anastasia Zekeridou   +11 more
wiley   +1 more source

Research on spacecraft electrical power conversion [PDF]

The steady state characteristics and starting behavior of some widely used self-oscillating magnetically coupled square wave inverters were studied and the development of LC-tuned square wave inverters is reported.
Wilson, T. G.
core   +1 more source