Results 61 to 70 of about 16,506 (255)

Static Voltage Stability Assessment of Electricity Networks Using an Enhanced Line-Based Index

Energies
High penetration of renewable energy sources complicates static voltage stability assessment, as conventional line-based indices are typically derived under restrictive assumptions, such as neglecting voltage-angle differences or decoupling active and ...
Zhiquan Zhou, Ashish P. Agalgaonkar, Kashem M. Muttaqi   +2 more
doaj   +1 more source

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

Molecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka, Wioleta Cieślik, Wojciech Płaziński, Katarzyna Stępnik, Anna Boguszewska‐Czubara, Elżbieta Kot, Robert Musioł, Mateusz Jasica, Anna Mrozek‐Wilczkiewicz, Katarzyna Malarz   +9 more
wiley   +1 more source

Liquid biopsy‐based diagnostic evaluation of hypermethylated CpG sites for ovarian cancer diagnosis

Molecular Oncology, EarlyView.
This schematic outlines the workflow from biomarker identification to duplex MethyLight assay validation for epithelial ovarian cancer diagnosis using cfDNA‐based liquid biopsy. Initial screening of hypermethylated CpG candidates (cg02957270, cg10061138 cg00480298, COL2A1) was performed in tissue using ARMS‐PCR, COBRA, qPCR and image analysis. Selected
Deepa Bisht, Sameer Gupta, Amrita Chaurasia, Manisha Sachan   +3 more
wiley   +1 more source

Epigenetic heterogeneity and plasticity in therapy‐induced tumor states through single‐cell multi‐omics

Molecular Oncology, EarlyView.
Single‐cell multi‐omics reveals epigenetic heterogeneity across therapy‐adaptive tumor states, including quiescent/dormant, drug‐tolerant persister, and EMT‐like phenotypes. By linking regulatory features with state‐associated biomarkers, these approaches inform biomarker‐guided therapeutic strategies for evolving tumors.
Hee Jung Kim, Hwiyeong Lee, Jin Hong, Daechan Park   +3 more
wiley   +1 more source

Comparative Analysis of Voltage Stability in Radial Power Distribution Networks Under Critical Loading Conditions and Diverse Load Models

Electricity
Modern power distribution systems are increasingly stressed as they operate closer to their voltage stability limits, driven by growing electricity demand, complex load behaviors, and the evolving structure of power networks. Radial distribution systems,
Salah Mokred, Yifei Wang
doaj   +1 more source

ZW4864‐mediated inhibition of the β‐catenin/BCL9/BCL9L complex reveals therapeutic potential in bladder cancer

Molecular Oncology, EarlyView.
BCL9 and BCL9L drive bladder cancer progression by enhancing β‐catenin signaling, promoting proliferation, migration, invasion, and organoid growth. Genetic depletion of BCL9(L) suppresses malignant phenotypes, while pharmacological disruption of the β‐catenin/BCL9(L) complex with ZW4864 inhibits canonical Wnt signaling and tumor‐associated cellular ...
Roland Kotolloshi, Mandy Berndt‐Paetz, Eileen Lerner, Gregoire Najjar, Anca Azoitei, Krishna Pal Singh, Shailendra Kumar Gupta, Olaf Wolkenhauer, Cagatay Günes, Otmar Huber, Marc‐Oliver Grimm, Daniel Steinbach   +11 more
wiley   +1 more source

Power System Voltage Stability Assessment and Control Strategies: State-of-the-Art Review

Journal of Electrical and Computer Engineering
Voltage stability is crucial for power systems, ensuring that electrical grids maintain voltages within acceptable limits with increasing demand, renewable energy integration, and changing network topology.
Yalew Gebru Werkie, George Nyauma Nyakoe, Cyrus Wabuge Wekesa   +2 more
doaj   +1 more source

An on-line power/voltage stability index for multi-infeed HVDC systems

Journal of Modern Power Systems and Clean Energy, 2019
High-voltage direct current (HVDC) transmission is playing an increasingly important role in modern power systems, and the resulted power/voltage stability issue has raised widespread concern. This paper presents an on-line power/voltage stability index (
Jian Xu, Tiankai Lan, Siyang Liao, Yuanzhang Sun, Deping Ke, Xiong Li, Jun Yang, Xiaotao Peng   +7 more
doaj   +1 more source

Polarization‐resolved femtosecond Vis/IR spectroscopy tailored for resolving weak signals in biological samples using minimal sample volume

FEBS Open Bio, EarlyView.
Unique biological samples, such as site‐specific mutant proteins, are available only in limited quantities. Here, we present a polarization‐resolved transient infrared spectroscopy setup with referencing to improve signal‐to‐noise tailored towards tracing small signals. We provide an overview of characterizing the excitation conditions for polarization‐
Clark Zahn, Karsten Heyne
wiley   +1 more source

Investigation of Voltage Stability Indices to Identify Weakest Bus (TBC) [PDF]

, 2012
This paper proposes a new index to determine the static voltage stability of the load buses in a power network for certain operating conditions and hence identifies load buses which are close to voltage collapse. The proposed index is formulated from the quadratic equation derived from a two-bus network and is computed using the apparent power and the ...
Jalboub, Mohamed K., Rajamani, Haile S., Liang, D.T.W., Abd-Alhameed, Raed, Ihbal, Abdel-Baset M.I.   +4 more
openaire   +2 more sources