Results 111 to 120 of about 569,472 (308)
FEBS Letters, EarlyView.We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley +1 more source
Active control of flexural vibrations in beams [PDF]
The feasibility of using piezoelectric actuators to control the flexural oscillations of large structures in space is investigated. Flexural oscillations are excited by impulsive loads.
Gerhold, Carl H.
core +1 more source
Low-voltage organic transistors and inverters with ultra-thin fluoropolymer gate dielectric
, 2009 We report on the simple fabrication of hysteresis-free and electrically stable organic field-effect transistors (OFETs) and inverters operating at voltages
Batlogg, B. +3 more
core +1 more source
Tau acetylation at K331 has limited impact on tau pathology in vivo
FEBS Letters, EarlyView.We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto +3 more
wiley +1 more source
FEBS Letters, EarlyView.This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel +13 more
wiley +1 more source
Irreversibility of Electrical Insulating Material Properties
Advances in Electrical and Electronic Engineering, 2007 Property changes in electrical insulating materials that appear during repeated voltage stress (e. g. in an applied voltage test) are an often discussed problem. The voltage exposure leads to irreversible changes in a negative sense as this investigation
Vaclav Mentlik, Radek Polansky
doaj
An Investigation of SILC Degradation under Constant Voltage Stress in PDSOI Devices. [PDF]
Micromachines (Basel), 2023 Lu Y, Liu H.
europepmc +1 more source
FEBS Letters, EarlyView.Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura +2 more
wiley +1 more source
Design of low stress and high efficiency asymmetric half-bridge converter
Dianzi Jishu Yingyong, 2018 Asymmetrical half bridge converter has problems that wide power output efficiency is not ideal, the voltage and current stress is large, and rectifier diode has voltage ringing problem. So a low stress and high efficiency asymmetric half-bridge converter
Yao Yueqin, Lu Zhengkai
doaj +1 more source
Parameters Design and Optimization of SiC MOSFET Driving Circuit with Consideration of Comprehensive Loss and Voltage Stress. [PDF]
Micromachines (Basel), 2023 Qin H +5 more
europepmc +1 more source