Results 31 to 40 of about 29,749 (262)
NKCC1: A key regulator of glioblastoma progression
Molecular Oncology, EarlyView.Glioblastoma (GBM) progression is driven by disrupted chloride cotransporter homeostasis. NKCC1 is highly expressed in stem‐like, astrocytic, and progenitor cells, correlating with earlier recurrence, while overall survival remains unaffected. NKCC1 serves as a prognostic marker and potential therapeutic target, linking chloride transporter imbalance ...
Anja Thomsen +5 more
wiley +1 more source
FEBS Open Bio, EarlyView.Mouse pre‐implantation development involves a transition from totipotency to pluripotency. Integrating transcriptomics, epigenetic profiling, low‐input proteomics and functional assays, we show that eight‐cell embryos retain residual totipotency features, whereas cytoskeletal remodeling regulated by the ubiquitin‐proteasome system drives progression ...
Wanqiong Li +8 more
wiley +1 more source
RRS Discovery Cruise DY017, 20 Oct - 05 Nov 2014. Outer Hebrides process cruise [PDF]
, 2015 The continental shelf region immediately west of the UK and North of Ireland is thought to be a key region for the exchange of nutrients, carbon and water between the NW European continental shelf and the open North Atlantic Ocean yet it remains ...
et al,, Painter, S.C.
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Single-phase series active conditioner for the compensation of voltage harmonics, sags, swell and flicker [PDF]
, 2011 Simulation and experimental results shown on this paper describes the performance of a developed Single-Phase Series Active Conditioner that regulates the voltage being delivered to a load.
Afonso, João L. +2 more
core +1 more source
Dapagliflozin prevents methylglyoxal‐induced retinal cell death in ARPE‐19 cells
FEBS Open Bio, EarlyView.Diabetic macular oedema is a diabetes complication of the eye, which may lead to permanent blindness. ARPE‐19 are human retinal cells used to study retinal diseases and potential therapeutics. Methylglyoxal is a compound increased in uncontrolled diabetes due to elevated blood glucose.
Naina Trivedi +7 more
wiley +1 more source
A micro cell lysis device [PDF]
, 1998 A new micromachined cell lysis device is developed. It is designed for miniature bio-analysis systems where cell lysing is needed to obtain intracellular materials for further analysis such as DNA identification.
Lee, S. W., Tai, Y. C., Yowanto, H.
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Mitigation of voltage sag and voltage swell by using dynamic voltage restorer
International Journal of Power Electronics and Drive Systems (IJPEDS)Recent power quality (PQ) research shows that the most common types of power quality disturbances are voltage sags and swells in medium and low-voltage distribution grids. This paper shows how to improve two significant power quality disturbances: sags and swells voltage. To find out what effect these two PQ issues have in real life, a study case based
El-Zahraa M. Mattar +2 more
openaire +1 more source
FEBS Open Bio, EarlyView.Early‐life exposure to a high‐fat diet altered intact Achilles tendons in rat offspring, making them thinner, stiffer, and molecularly distinct even without injury. These findings suggest that developmental high‐fat diet exposure may impair tendon quality and increase susceptibility to mechanical overload or tendon injury later in life.
Heyong Yin +3 more
wiley +1 more source
Incremental learning for large-scale stream data and its application to cybersecurity [PDF]
, 2015 As many human currently depend on technologies to assist with daily tasks, there are more and more applications which have been developed to be fit in one small gadget such as smart phone and tablet.
Ali, Siti Hajar Aminah
core
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective This study aims to identify both fluid and neuroimaging biomarkers for CSF1R‐RD that can inform the optimal timing of treatment administration to maximize therapeutic benefit, while also providing sensitive quantitative measurements to monitor disease progression.
Tomasz Chmiela +13 more
wiley +1 more source