Results 141 to 150 of about 119,844 (307)

CD47 promotes mitogen‐activated protein kinase and epithelial‐to‐mesenchymal transition molecular programs to drive prometastatic phenotypes in non‐small cell lung cancer

open access: yesMolecular Oncology, EarlyView.
Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau   +8 more
wiley   +1 more source

The Study of Several Variants of the Traction Drive with Middle-Frequency Transformer

open access: yesAdvances in Electrical and Electronic Engineering, 2008
This paper presents research motivated by industrial demand for special traction drive topology devoted to minimization of traction transformer weight of traction vehicles.
Martin Pittermann   +3 more
doaj  

Voltage Compensation-Type Current Limiter Based on Hybrid Distribution Transformer for Power Quality Enhancement

open access: yesEAI Endorsed Transactions on Energy Web
This paper presents a voltage compensation-type current limiter based on a hybrid distribution transformer (HDT) structure, which integrates a three-winding transformer, AC/DC converter, DC/AC converter, current-limiting unit, bypass switches, and a ...
Ruiayo Wang   +4 more
doaj   +1 more source

Elimination of current spikes in buck power converters [PDF]

open access: yes, 1981
Current spikes in a buck power converter due to commutating diode turn-off time are eliminated by using a tapped inductor in the converter with the tap connected to the switching transistor. The commutating diode is not in the usual place, but is instead
Mclyman, W. T.
core   +1 more source

Electronic-Based High-Voltage Measuring Transformers

open access: yesIEEE Power Engineering Review, 2002
A new electronic system to assist high-voltage measuring transformers is proposed. This system compensates the voltage drops in the series impedances of the transformer, which are the main cause of errors at power frequency. The nonlinear behavior of the magnetizing branch has no influence on the results.
openaire   +2 more sources

KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer

open access: yesMolecular Oncology, EarlyView.
Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan   +16 more
wiley   +1 more source

Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer

open access: yesMolecular Oncology, EarlyView.
Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley   +1 more source

Analysis and engineering calculation of excitation inrush current characteristics of high voltage built-in high impedance transformer

open access: yesDiance yu yibiao
This paper presents a calculation scheme of inrush current of high voltage built-in high impedance transformer which takes into account the nonlinear changes of remanence and excitation inductance.
RONG Chunyan   +5 more
doaj   +1 more source

Transcriptional profiling of circulating extracellular vesicles from prebiopsy prostate cancer patients

open access: yesMolecular Oncology, EarlyView.
RNA profiling of circulating extracellular vesicles (EVs) from blood samples of men undergoing prostate biopsy identifies transcripts associated with clinically significant prostate cancer. Integrative analysis with public tumor datasets links EV‐derived gene signatures to tumor stage and progression‐free survival, highlighting CASP3, XRCC2, and RIT1 ...
Stefan Werner   +14 more
wiley   +1 more source

Insights into a long life without cancer: The case of the bowhead whale

open access: yesMolecular Oncology, EarlyView.
Long‐lived, large‐bodied organisms have evolved powerful anticancer mechanisms that preserve cellular and tissue integrity across extended lifespans. A recent study by Firsanov et al. shows that greater genome stability is a key factor underlying the remarkable longevity and cancer resistance of one such species, the bowhead whale.
Inés Paniagua, Johanna A. Joyce
wiley   +1 more source

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