Results 101 to 110 of about 79,309 (294)

Evolutionarily divergent DUF4465 domains have a common vitamin B12‐binding function

FEBS Open Bio, EarlyView.
We show that DUF4465 family proteins, widespread across bacteria from gut microbiomes, hydrothermal vents, and soil, share a common vitamin B12‐binding function. These augmented β‐jellyroll proteins bind vitamin B12 via extended loops. Our findings establish sequence‐diverse DUF4465 proteins as a widespread class of B12‐binding proteins, highlighting ...
Charlea Clarke, Michal Banasik, Rokas Juodeikis, Martin J. Warren, Richard W. Pickersgill   +4 more
wiley   +1 more source

Integrated PV and multilevel converter system for maximum power generation under partial shading conditions [PDF]

, 2013
The emerging trend towards the harnessing of the electrical power from solar energy has increased the research effort in power electronics applications.
Abdalla, Imadeddin Abdalla
core  

Large‐scale bidirectional arrayed genetic screens identify OXR1 and EMC4 as modifiers of αSynuclein aggregation

FEBS Open Bio, EarlyView.
Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane, Lea Nikolić, Lorenzo Maraio, Thomas Goiran, Nathan Karpilovsky, Stefano Sellitto, Vangelis Bouris, Jiang‐An Yin, Ronald Melki, Edward A Fon, Adriano Aguzzi, Elena De Cecco   +11 more
wiley   +1 more source

Identifying transcription factors controlling the basal expression of human MRP4 highlights a substantial role for Sp1

FEBS Open Bio, EarlyView.
The MRP4 transporter exports several drugs and signaling molecules. Here, we identified key promoter elements regulating basal MRP4 expression. Using reporter assays, we defined a conserved region with essential Sp1 and contributory Ets sites, which controlled basal MRP4 expression.
Debora Singer, Angelique Kragl, Katrin Ziems, Juliane Glaubitz, Sophie Grammbauer, Susanne Hildebrandt, Mladen V. Tzvetkov, Gabriele Jedlitschky   +7 more
wiley   +1 more source

Voltage quality enhancement of distribution network based on unified power quality conditioner with BESS

Frontiers in Energy Research
This article proposes a voltage compensation control strategy for the distribution network based on the unified power quality conditioner (UPQC) with battery energy storage systems (BESS) to achieve comprehensive management of the power quality and ...
Yan Mei, Jiangbo Xu, Chen Peng, Weikang Kong, Gang Peng, Guangyu Song   +5 more
doaj   +1 more source

Static Voltage Stability Analysis by Using SVM and Neural Network [PDF]

Journal of Intelligent Procedures in Electrical Technology, 2013
Voltage stability is an important problem in power system networks. In this paper, in terms of static voltage stability, and application of Neural Networks (NN) and Supported Vector Machine (SVM) for estimating of voltage stability margin (VSM) and ...
Mehdi Hajian, Asghar Akbari Foroud, Hossein Norouzian   +2 more
doaj  

Measurement of Voltage Distribution on High Voltage Suspension Insulator String Under Polluted Condition [PDF]

, 2015
From electrical engineering point of view insulator plays an important role. As it is used as basic element in overhead transmission and distribution networks.
Samal, Simanta Kumar
core  

Derivation and characterization of retinal pigment epithelium from urine‐derived iPSCs

FEBS Open Bio, EarlyView.
Age‐related macular degeneration causes vision loss via RPE dysfunction and loss. Traditional iPSC therapies rely on invasive biopsies, limiting scalability. Here, we utilize urine‐derived stem cells as an accessible source to generate u‐iPSCs, successfully differentiated into pigmented RPE. This “Urine‐to‐Retina” platform provides a promising path for
Daniella Beiner, Hainan Zhu, Carol Christine Bosholm, Heuy‐Ching Wang, Tracy Criswell, Anthony Atala, Jian‐Xing Ma, Yuanyuan Zhang   +7 more
wiley   +1 more source

Molecular dynamics simulations of positively selected codons in FcγRI reveal novel biochemical binding properties

FEBS Open Bio, EarlyView.
Evolutionary analysis across 32 placental mammals identified positive selection at residues H148 and W149 in the immune receptor FcγR1. Ancestral reconstruction combined with molecular dynamics simulations reveals how these mutations may influence receptor structure and dynamics, providing insight into the evolution of antibody recognition and immune ...
David A. Young, Omar Arias‐Gaguancela, Fiona Gibson, Morgan Grainger, Jodie Score, Amit Nathubhai, Mauricio Cafiero, Lee Richard Machado   +7 more
wiley   +1 more source

Experimental Implementation of a 3-Level TNPC-IGBT Inverter for Uniform Stress Distribution and THD Mitigation: MPC-Driven Switching Optimization, LCL Filter Integration, and Real-Time Stress Monitoring

IEEE Access
The increasing demand for high-quality power conversion in industrial applications has led to advancements in multilevel inverter design and control. This paper presents a design and experimental implementation of a 3-level T-type neutral-point clamped ...
Ahmed H. Okilly, Cheolgyu Kim, Jeihoon Baek   +2 more
doaj   +1 more source