Results 51 to 60 of about 471,690 (262)

A Volume-of-Fluid based simulation method for wave impact problems [PDF]

open access: yesJournal of Computational Physics, 2005
zbMATH Open Web Interface contents unavailable due to conflicting licenses.
Kleefsman, K.M.T.   +4 more
openaire   +3 more sources

Degradation mechanism of the von Willebrand factor A2 domain by nattokinase

open access: yesFEBS Letters, EarlyView.
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto   +3 more
wiley   +1 more source

Modulation of Homer1 EVH1 domain internal dynamics by putative autism‐associated mutations

open access: yesFEBS Letters, EarlyView.
The putative autism‐associated M65I and S97L variants of the EVH1 domain of the postsynaptic scaffold protein Homer1 do not exhibit substantial changes in their overall structure or partner binding. Both of them, but especially the M65I variant, show altered internal dynamics relative to the wild‐type domain on the μs‐ms timescale, indicated by the ...
Fanni Farkas   +6 more
wiley   +1 more source

An unexpected alternative viologen electron mediator site in tungsten‐containing formate dehydrogenase

open access: yesFEBS Letters, EarlyView.
An unexpected alternative interaction site for ethyl viologen was identified in formate dehydrogenase 1 from Methylorubrum extorquens. Combined mutagenesis, kinetic analysis, and docking revealed that aromatic residues near an iron–sulfur cluster enable flavin mononucleotide‐independent electron transfer, offering a framework for engineering improved ...
Eleni G. Poloniataki, Yong Hwan Kim
wiley   +1 more source

Salmonella lipopolysaccharide‐containing supported lipid bilayers as platforms to study bacteriophage interactions

open access: yesFEBS Letters, EarlyView.
We present robust protocols for the preparation of supported lipid bilayers (SLBs) incorporating either Salmonella smooth LPS or outer membrane vesicles (OMVs). We use a combination of quartz crystal microbalance with dissipation (QCM‐D) and fluorescence microscopy to both characterize the SLBs of various compositions and to probe their interactions ...
Hudson P. Pace   +6 more
wiley   +1 more source

SIMPLIFIED VOLUME OF FLUID METHOD (SVOF) FOR TWO-PHASE FLOWS

open access: yesTASK Quarterly, 2008
The PLIC approach has been usually used in recent implementations of the VOF method i.e. the interphasal surface is approximated by a plane with an arbitrary orientation with respect to the computational cell.
MACIEJ MAREK   +2 more
doaj  

Numerical Investigation of Cylindrical Water Droplets Subjected to Air Shock Loading at a High Weber Number

open access: yesFluids
This work is devoted to the computational investigation of the deformation and breakup of cylindrical water bodies in the high-speed airflow behind incident shock waves.
F. Edoardo Taglialatela   +1 more
doaj   +1 more source

Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis

open access: yesFEBS Letters, EarlyView.
Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee   +7 more
wiley   +1 more source

Investigating the Effect of Free Surface on Hydrodynamic Performance of Propeller

open access: yesنشریه مهندسی دریا, 2019
Simulation of the flow around propeller is a complex fluid flow problem, especially when the propeller is close to free surface. In this study, the effect of different depths on the performance and efficiency of a B-Wageningen series close to surface of ...
Mohammad Hasan Zare   +3 more
doaj  

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