Results 81 to 90 of about 471,690 (262)

Numerical investigation of gas film evolution and drag reduction mechanisms on micro/nano-structured superhydrophobic surfaces

open access: yesApplied Ocean Research
Underwater drag reduction is critical for improving the speed and energy efficiency of marine vehicles. Gas films on superhydrophobic surfaces (SHS) exhibit complex dynamics under turbulent flow, and their interfacial destabilization remains a central ...
Shihao Yuan   +6 more
doaj   +1 more source

Circulating microRNA signatures of cachexia and cancer in Canis familiaris as a comparative oncology model for human disease

open access: yesMolecular Oncology, EarlyView.
Circulating microRNAs as biomarkers of cachexia and sex‐specific cancer in senior dogs. In 25 client‐owned dogs, four circulating miRNAs (miR‐15a, miR‐15b, miR‐16, miR‐140) were downregulated in cachexia, with miR‐16 the strongest individual biomarker (AUC = 0.899).
Soon‐Seok Park   +6 more
wiley   +1 more source

Preoperative circulating tumor cells integrated with imaging analysis for prognostic evaluation in head and neck squamous cell carcinoma

open access: yesMolecular Oncology, EarlyView.
Detecting circulating tumor cells (CTCs) in blood before surgery may help predict outcomes in patients with head and neck squamous cell carcinoma (HNSCC). Here, we show when combined with tumor size and lymph node involvement from routine imaging, CTC status identifies high‐risk patients with poorer survival—offering a simple, minimally invasive tool ...
Susanne Flach   +9 more
wiley   +1 more source

A periodic representation of the interface for the volume of fluid method

open access: yes, 2011
We extend the volume of fluid method for the computation of two-phase flow to a higher order accurate method in two dimensions. The interface reconstruction by the PLIC method is thereby replaced by a periodic interface reconstruction. The advection step is reformulated and extended to higher order in order to account for the present interface ...
openaire   +2 more sources

Single‐cell DNA methylation profiling: Technologies, computation, and applications in precision oncology

open access: yesMolecular Oncology, EarlyView.
Single‐cell DNA methylation (scDNAme) profiling maps epimutational clonal evolution, revealing mechanisms of malignancy and therapeutic resistance across diverse cancer types. By providing a high‐resolution landscape of intratumoral heterogeneity, these technologies empower precise patient stratification, guide the development of enhanced ...
Ik Soo Kim
wiley   +1 more source

Computational Modeling of Bubbles Growth Using the Coupled Level Set-Volume of Fluid Method. [PDF]

open access: yesEur J Mech B Fluids, 2020
Taqieddin A   +3 more
europepmc   +1 more source

Pharmacological chromatin remodeling enhances response to estrogen therapy in ER+ breast cancer

open access: yesMolecular Oncology, EarlyView.
Estrogen therapy elicits clinical benefit in ~ 30% of patients with endocrine‐resistant estrogen receptor (ER)‐positive breast cancer. Based on findings that ER transcriptional activation underlies response to estrogen therapy, we tested the effects of epigenetic dysregulation via pharmacological inhibition of histone deacetylases (HDACi).
Anneka L. Johnson Thomas   +16 more
wiley   +1 more source

Spatial biology in cancer epigenetics

open access: yesMolecular Oncology, EarlyView.
Spatial epigenomics combines molecular profiling with tissue architecture to reveal how gene regulation is organized within intact tissues. In cancer, these technologies uncover the mechanisms driving tumor heterogeneity and microenvironmental interactions, opening new opportunities for biomarker discovery and precision medicine.
Eva Crespo‐García, Manel Esteller
wiley   +1 more source

Comparison between the single deepest pocket and amniotic fluid index in predicting fetal distress in small‐for‐gestational age fetuses

open access: yesActa Obstetricia et Gynecologica Scandinavica, 1997
Background. The relationship between reduced amniotic fluid volume and increased risk of fetal distress in small‐for‐gestational age fetuses is not yet clear. Furthermore, the criteria used for the diagnosis of ‘oligohydramnios’ are different between the
Tsunetake Miyamura   +3 more
doaj   +1 more source

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