Results 231 to 240 of about 8,374,598 (297)

Reflections on speech-language-hearing therapy in obesity and bariatric surgery. [PDF]

Codas
Costa SLSCA, Cruz IJADS, Santana PMA, Duarte MDG, Althoff KNFP.   +4 more
europepmc   +1 more source

Selective elimination of quiescent cancer cells by dequalinium chloride via ROS‐mediated ferroptosis

FEBS Open Bio, EarlyView.
Dequalinium chloride (DQ) selectively eliminates quiescent cancer cells (QCCs) by amplifying mitochondrial ROS. QCCs exhibit elevated basal ROS and limited redox‐buffering capacity, making them vulnerable to further ROS increases. DQ‐induced ROS exceeds the tolerance threshold, triggering lipid peroxidation and ferroptosis, whereas proliferating cells ...
Kotaro Miyamoto, Shiori Sakai, Minori Endo, Terigele, Mizuho Niibori, Taiki Morita, Yu Goto, Arisa Yoshida, Tomohiro Tanaka, Ning Lin, Takahiro Kuchimaru, Hiroyuki Nakamura, Masahiro Inoue, Shinae Kizaka‐Kondoh, Tetsuya Kadonosono   +14 more
wiley   +1 more source

Position Statement on Cardiometabolic Health Across the Woman's Life Course - 2025. [PDF]

Arq Bras Cardiol
Oliveira GMM, Almeida MCC, Valério CM, Giuffrida F, Espíndola Neto L, Izar MCO, Marques-Santos C, Freire CMV, Albuquerque CJDM, Chagas ACP, Précoma DB, Mesquita ET, Saraiva JFK, Costa MENC, Lemke VMG, Lucena AJG, Brandão AA, Paiva Fagundes Junior AA, Macedo AVS, Polanczyk CA, Leitão CB, Silveira DS, Coutinho EDR, Nahas EAP, Alexandre ERG, Campana EMG, Bragança EOV, Colombo FMC, Barbosa ICQ, Rivera IR, Kulak Junior J, Salles JEN, Sá JR, Soares Júnior JM, Dourado LA, Moura LZ, Magalhães LBNC, Pompei LM, Passaglia LG, Assad MHV, Rodrigues MAH, Rivera MAM, Lopes MAAAM, Paiva MSMO, Castro ML, Campos MDSB, Souza OF, Medeiros OO, Freitas RAP, Carvalho RCM, Silva SCTFD, Rodrigues TCV, Avila WS, Silva Júnior WSD, Nazima WI, Costa-Paiva LHSD, Wender MCO.   +56 more
europepmc   +1 more source

TRPML1 agonist ML‐SA5 attenuates pulmonary fibroblast activation by suppressing mTOR and restoring autophagic flux

FEBS Open Bio, EarlyView.
TGF‐β1 stimulation downregulates lysosomal channel TRPML1 in pulmonary fibroblasts. The TRPML1 agonist ML‐SA5 suppressed fibroblast‐to‐myofibroblast activation and collagen production. Mechanistically, ML‐SA5 inhibited mTOR phosphorylation, restored autophagic flux, and its effects were enhanced by rapamycin (mTOR inhibitor) and reversed by MHY1485 ...
Jiatong Yao, Xiaoting Kang, Lulu Meng, Shaoxuan Zhang, Qiujie Li, Jinyu Zhou, Mengyue Xue, Chu Li, Hua Zhu, Pengzhou Hang, Jing Zhao   +10 more
wiley   +1 more source

Outcomes of Active Treatment for Localised Prostate Cancer After Holmium Laser Enucleation of the Prostate: A Systematic Review and Meta-analysis. [PDF]

Eur Urol Open Sci
Artiles Medina A, Tagalos Muñoz A, Domínguez Gutiérrez A, Muriel García A, Subiela JD, Álvarez Díaz N, Fernández Conejo G, Gómez Dos Santos V, Coloma Del Peso A, Burgos Revilla FJ.   +9 more
europepmc   +1 more source

Using fluorescence fluctuation spectroscopy to quantify molecular dynamics within cells

FEBS Open Bio, EarlyView.
Microscopy techniques like fluorescence correlation spectroscopy (FCS) and number and brightness analysis (N&B) allow to quantify concentrations, diffusion rates, and oligomerization of fluorescently labeled molecules in the living cell. In this protocol the principles of how to set up these types of experiments are described including calibration ...
Mark A. Hink
wiley   +1 more source

Predicting global and regional respiratory response in ARDS patients through individualized physics-based computational lung models: A prospective clinical pilot study

Sablewski A, Ludwig M, Eichinger C, Lindner M, Frerichs I, Langguth P, Schädler D, Wall WA, Becher T.   +8 more
europepmc   +1 more source

I - Evaluation of Cardiovascular Autonomic Function in Healthy Individuals. [PDF]

Arq Bras Cardiol
Maciel BC, Gallo-Jr L, Schmidt A, Marin-Neto JA.   +3 more
europepmc   +1 more source

A Low Psoas Muscle Index Was Associated With a Poorer Overall Survival in Patients Who Underwent Percutaneous Nephrostomy

Aging and Cancer, EarlyView.
In patients with malignant ureteral obstruction undergoing percutaneous nephrostomy, sarcopenia defined by a low psoas muscle index was independently associated with poor overall survival on multivariate Cox regression analysis, suggesting that preoperative assessment of psoas muscle index may aid prognostic stratification in this population.
Kota Shimokihara, Takashi Kawahara, Kazuhide Makiyama, Hiroji Uemura   +3 more
wiley   +1 more source

Efeito de dois alimentos comerciais secos e dois fornecimentos no consumo alimentar, pesos vivo e metabólico, escore corporal, escore e volume fecal de cães adultos em atividade. [PDF]

, 2015
openaire   +1 more source